Hormone disrupting effects of nonylphenol ethoxylates on 17 ß – estradiol levels and ovary in Zebra cichlid ( Cichlasoma nigrofasciatum )
Subject Areas : Marine BiologyT. Maktabi 1 , M. Roostaie 2 , M. Mahdavi 3 , N. Nasiri 4 , H. Hosseinzadeh Sahhafi 5
1 - Dept. of Marine Biology, Faculty of Marine Science and Technology, Islamic Azad University Tehran North branch
2 - Dept. of Animal Science, Islamic Azad University Saveh branch
3 - Dept. of Marine Biology, Faculty of Marine Science and Technology, Islamic Azad University Sciences and Researches branch
4 - Islamic Azad University Varamin branch
5 - Islamic Azad University Varamin branch
Keywords: oocytes, Cichlasoma nigrofasciatum, Nonylphenolethoxylate, hormone disruptor,
Abstract :
The present study investigatedsexually disrupting effects of a weak estrogen receptor agonist, nonylphenolethoxylale on 17 ß – estradiolproduction and ovary tissue in immatureZebra Cichlid (Cichlasoma nigrofasciatum). To determine the effects ofnonylphenol ethoxylale ( NPEO ) on female sex hormone of Zebra cichlid, the fish were divided in 3weight groups ( < 4 g , 4 – 5 g and > 5 g ) and exposed to threeconcentrations ( 10 – 50 – 100 µg / L ) of NPEO in glass aquariums during 60days. At an estimated NPEO concentration of 50 and 100 µg / L, 17 ß – estradiolproduction significantly was increased (P < 0.01). Specialchanges were showed in 50 µg / L. Estadiol levels were 0.13 –0.70 ng /ml. Thisevidence of steroid hormone (17 ß – estradiol) levels showed that nonylphenolethoxylate (>10 µg / L ) could exert estrogenic effects through geneexpression and producting enzymes involving vitellogenesis and lead toproduction of grown oocytes in 50 µg / L of nonylphenol ethoxylale.
