Abstract :
The interaction of Re )I( tricarbonyl-diimine complex )]Re[( with calf thymus DNA (CT-DNA) was investigated by using UV–Vis, fluorescence spectrophotometry, circular dichroism )CD( spectroscopy, thermal denaturation, and cyclic voltammetry )CV( studies. The binding constant value Kb of complex ]Re[ was found to be 5.47×106 M-1 using UV-Vis spectrophotometry data. The results show that the ]Re[ complex has relatively good interaction in comparison to other Schiff base complexes, indicating that the ]Re[ complex binds to DNA by electrostatic and partial intercalation modes. In addition, the intercalation mode is dominant via electrostatic interaction, as the most experiments confirm it
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