Synthesis of magnetic activated mesoporous carbons (Fe3O4/AC) using sesame waste as the green antibiotic adsorbent of azithromycin and optimization of effective parameters by design of experiment

Subject Areas :

mohamad hossein fekri ¹ (استادیار شیمی فیزیک، گروه شیمی، دانشکده علوم پایه، دانشگاه آیت‌الله بروجردی، بروجرد، ایران.)
maryam razavi mehr ² (Department of Chemistry, Faculty of Basic Sciences, Ayatollah Borujerdi University, Borujerd, Iran.)
samaneh Isanejad Mohamareh ³ (Department of Chemistry, Faculty of Basic Sciences, Ayatollah Borujerdi University, Borujerd, Iran.)
mohammad sharif zaerei ⁴ (Department of mechanic, Faculty of Engineering, Ayatollah Borujerdi University, Borujerd, Iran.)

Received: 2020-10-03 Accepted : 2020-12-15 Published : 2021-11-22

Keywords: Sesame, Azithromycin, Green method, Design Expert, Magnetic activated carbon,

Abstract :

In this study, carbon was extracted using sesame plant waste and activated carbon was obtained by ZnCl2. Magnetic Fe3O4 nanoparticles were loaded by in situ method onto activated carbon. Magnetic activated carbon (MGAC) was used to remove the azithromycin antibiotic. The results show that magnetically activated carbon is formed in nanoscale and and the size of the nanopores is about 26 nanometers. Its specific surface area is 112.23 m2g-1, which is a desirable and acceptable. Optimization of the important factors in the adsorption of azithromycin on magnetic activated carbon was performed by Design Expert 7 software and respons surface method. using Box-Behnken design method, the effect of three effective factors of pH, adsorbent dosage and temperature were investigated. Their optimal values were 2, 0.08 g and 85 °C, respectively, which by considering absorption percent of the drug by the adsorbent is 99 %. In these optimal conditions, the amount of drug absorption was obtained 97.83% experimentally.

References:

[1] Martinez, J.L.; Environ. Pollut. 157, 2893-902, 2009.

[2] Emad, S.E.; Chaudhur, M.; Desalin. 272, 218-24, 2011.

[3] Emad, S.E.; Chaudhuri, M.; Desalin. 256, 43-47, 2010.

[4] Kümmerer, K.; Chemosphere 75, 417-34, 2009.

[5] Emad, S.E.; Chaudhuri, M.; Desalin. 256, 43-47, 2010.

[6] Amsaleg, C.; Laverman, A.M.; Environ. Sci. Pollut. Res. 23, 4000-4012, 2016.

[7] Homem, V.; Santos, L.; J. Environ. Manage. 92, 2304- 47, 2011.

[8] Dashti Khavidaki, H.; Fekri, M.H.; J. Adv. Chem. 11, 3777-3788, 2015.

[9] Razavi Mehr, M.; Fekri, M.H.; Omidali, F.; Eftekhari, N.; Akbari-adergani, B.; J. Chem. Health Risks 9, 75-86, 2019.

[10] Fekri, M.H.; Banimahd Keivani, M.; Razavi Mehr, M.; Akbari-adergani, B.; J.

Mazandaran Univ. Med. Sci. 29, 166-179, 2019.

[11] Shen, S.; Ren, J.; Chen, J.; Lu, X.; Deng, C.; Jiang, X.; J. Chromatogr. A 1218, 4619-26, 2011.

[12] Iram, M.; Guo, C.; Guan, Y.; Ishfaq, A.; Liu, H.; J. Hazard. Mater. 181, 1039-50, 2010.

[13] Qu, S.; Huang, F.; Yu, S.; Chen, G.; Kong, J.; J. Hazard. Mater. 160, 643-47, 2008.

[14] Chegeni, M.; Etemadpour, S.; Fekri, M.H.; Phys. Chem. Res. 9(1), 1-16, 2021.

[14] Burchell, D. T., “Carbon materials for advanced technologies”, Elsevier Science Ltd, 1999.

[15] Ai, L.; Huang, H.; Chen, Z.; Wei, X.; Jiang, J.; Chem. Eng. J. 156, 243-249, 2010.

[16] Yegane Badi, M.; Azari, A.; Pasalari, H.; Esrafili, A.; Farzadki, M.; J. Mol. Liq. 261, 146–154, 2018.