Polymorphisms in GDF9 Gene and Its Relationship with Litter Size in Five Breeds of Black Goats

Subject Areas : Camel

G.Q. Zhu ¹ , Q.I. Wang ² , Y.G. Kang ³ , Y.Z. Lv ⁴ , B.Y. Cao ⁵

1 - Department of Animal Engineering, Xuzhou Bioengineering Technical College, 221006, Xuzhou, China College of Animal Science and Technology, Northwest A and F University, Yangling, 712100, Shaanxi, China
2 - Department of Animal Engineering, Xuzhou Bioengineering Technical College, 221006, Xuzhou, China
3 - Department of Animal Engineering, Xuzhou Bioengineering Technical College, 221006, Xuzhou, China
4 - Department of Animal Engineering, Xuzhou Bioengineering Technical College, 221006, Xuzhou, China
5 - College of Animal Science and Technology, Northwest A and F University, Yangling, 712100, Shaanxi, China

Received: 2012-05-01 Accepted : 2012-09-27 Published : 2013-09-01

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References:

Armeiro L.C.M., Curi R.A. Chardulo L.A.L., Puoli Filho J.N.P. and Silveira da Mota M.D. (2012). Polymorphisms of candidate genes for muscle perform and male fertility in Brazilian Mangalarga horses. Iranian J. Appl. Anim. Sci. 2, 199-202.
Bodin L., Pasquale E.D., Fabre S., Bontoux M., Monget P., Persani L. and Mulsant P. (2007). A novel mutation in the bone morphogenetic protein 15 gene causing defective protein secretion is associated with both increased ovulation rate and sterility in Lacaune sheep. Endocrinology. 148, 393-400.
Chu M.X., Li B.X., Wang J.Y., Ye S.C. and Fang L. (2004). Association between PCR-SSCP of growth differentiation factor 9 gene and high prolificacy in small tailed Han sheep. Anim. Bitechno. 15,111-120.
Chu M.X., Jiao C.L., He Y.Q., Wang J.Y., Liu Z.H. and Chen G.H. (2007). Association between PCR-SSCP of bone morphogenetic protein 15 gene and prolificacy in Jining Grey goats. Anim. Biotechnol. 18, 263-274.
Chu M. X., Sang L. H., Wang J. Y., Fang L. and Ye S.C. (2005). Study on BMP15 and GDF9 as candidate genes for prolificacy of small tail Han sheep. Yi. Chuan. Xue. Bao. 32,38-45.
Clelland E., Kohli G., Campbell R.K., Sharma S., Shimasaki S. and Peng C. (2006). Bone morphogenetic protein-15 in the Zebrafish ovary: complementary deoxyribonucleic acid cloning, genomic organization, tissue distribution, and role in oocyte maturation. Endocrinology. 147, 201-209.
DavisG.H. (2005). Major genes affecting ovulation rate in sheep. Genet. Sel. Evol. 37, 11-23.
Dong J., Albertini D.F., Nishimori K., Kumar T.R., Lu N. and Matzuk M.M. (1996). Growth differentiation factor-9 is required during early ovarian folliculogenesis. Nature. 383, 531-535.
Dube J.L., Wang P., Elvin J., Lyons K.M., Celeste A.J. and Matzuk M.M. (1998). The bone morphogenetic protein 15 gene is X-linked and expressedin oocytes. Mol. Endocrinol. 12, 1809-1817.
Du Z.Y., Lin J.B., Qin C., Wang J.F. and Ran X.Q. (2008). Polymorphism of exon 2 of growth differentiation factor 9 gene Guizhou white goats. Anim. Husb. Vet. Med. 40,46-48.
Elis S., Dupont J., Couty I., Persani L., Govoroun M., Blesbois E., Batellier F. and Monget P. (2007). Expression and biological effects of bone morphogenetic protein-15 in the hen ovary. Endocrinology. 194, 485-497.
Galloway S.M., Mc Natty K.P., Cambridge L.M., Laitinen M.P., Jennifer J.L., Jokiranta S., Mc Laren R.J., Luiro K., Dodds K.G., Montgomery G.W., Beattie A.E., Davis G.H. and Ritvos O. (2000). Mutations in an oocyte derived growth factor gene (BMP15) cause increased ovulation rate and infertility in a dosage-sensitive manner. Nat. Genet. 25, 279-283.
Hanrahan P.J., Gregan, S.M., Mulsant P., Mullen M., Davis G.H., Powell R. and Galloway S.M. (2004). Mutations in the genes for oocyte-derivedgrowth factors GDF9 and BMP15 are associated with both increased ovulation rate and sterility in cambridge and belclare sheep (Ovis aries). Biol. Reprod. 70, 900-909.
Hua G.H., Chen S.L., Ai J.T. and Yang L.G. (2008). None of polymorphism of ovine fecundity major genes FecB and FecX was tested in goat. Anim. Reprod. Sci. 108, 279-286.
Hua G.H. and Yang L.G. (2009). A review of research progress of FecB gene in Chinese breeds of sheep. Anim. Reprod. Sci. 116, 1-9.
Johnson P.A., Dickens M.J., Kent T.R. and Giles J.R. (2005). Expression and function of growth differentiation factor-9 in an oviparous species, gallus domesticus. Biol. Reprod. 72, 1095-1100.
Ji Y.T., Qu C.Q. and Cao B.Y. (2007). An optimal method of DNA silver staining in polyacrylamide gels. Electrophoresis. 28, 1173-1175
Li B.X., Chu M.X. and Wang J.Y. (2003). PCR-SSCP analysis on growth differentiation factor 9 gene in sheep. J. Genet. Genom. 30, 307-310.
Liu L. and Ge W. (2007). Growth differentiation factor 9 and its spatiotemporal expression and regulation in the Zebrafish ovary. Biol. Reprod. 76, 294-302.
Lin J.B., Du Z.Y., Qin C., Wang J.F. And Ran X.Q. (2007). Polymorphism of BMP15 gene in Guizhou white goats. Anim. Husb. Vet. Med. 39, 21-24.
Mc Natty K.P., Juengel J.L., Reader K.L., Lun S., Myllymaa S., Lawrence S.B., Western A., Meerasahib M.F., Mottershead D.G., Groome N.P., Ritvos O. and Laitinen M.P. (2005). Bone morphogenetic protein 15 and growth differentiation factor 9 cooperate to regulate granulosa cell function. Reproduction. 129, 473-480.
Silva J.R.V., Hurk R.V.D., Tol H.T.A., Roelen B.A.J. and Figueiredo J.R. (2004). Expression of growth differentiation factor 9 (GDF9), bone morphogenetic protein 15 (Bmp15), and BMP receptors in the ovaries of goats.Mol. Reprod. Dev. 70, 11-19.
Sambrook J. and Russel D.W. (2002). Molecular Cloning a Laboratory Manual.Science Press, Beijing, China.
Wu Z.H. (2005). Study the polymorphism of hircine growth differentiation factor 9 genes and the relation of Jining Grey Goat prolificacy. MS Thesis. Agri. Univ. Sichuan, Ya'an, China.
Yang J. (2006). Polymorphisms of GDF9 and BMP15 genes and their relationships with prolificacy in small tail Han sheep. MS Thesis. Chinese Acad. Agri. Sci., Beijing, China.