• فهرس المقالات glucogenic precursor

      • حرية الوصول المقاله

        1 - Performance, Metabolic Responses of Fresh Cows to Daily or Every Other Day Oral Drenching a Glucogenic Precursor
        م. کاظمی بن چناری م. جهانی مقدم ع.ر. علیزاده پ. قدرتی ح. شهابی ا. محجوبی م. گرجی دوز
        The delivery method of [continuous (CONT) vs. every other day or intermittent (INT)] a glucogenic precursor (GP) which was contained glycerin (500 g/kg), mono-propylene glycol (250 g/kg), calcium propionate (150 g/kg), niacin (1 g/kg) and sulfate-Co (350 mg/kg) on perfo أکثر
        The delivery method of [continuous (CONT) vs. every other day or intermittent (INT)] a glucogenic precursor (GP) which was contained glycerin (500 g/kg), mono-propylene glycol (250 g/kg), calcium propionate (150 g/kg), niacin (1 g/kg) and sulfate-Co (350 mg/kg) on performance, selected blood metabolites and liver enzymes were evaluated. Twenty-four multiparous Holstein fresh cows were allocated in a completely randomized design (8 animals/each treatment) fed individually for a period of 14 days after calving. The experimental groups were: 1) no GP supplementation (CTR), 2) GP offered as an oral drench once a day (GP-CONT) on days 3, 4, 5, 6, and 7 after calving and 3) GP offered as an oral drench once a day intermittently (GP-INT) on days 3, 5, 7, 9, and 11 after calving. The amount of oral drenched GP was 1 kg/d. Blood samples were obtained on 5 and 14 days in milk. Dry matter intake (DMI) was increased (P=0.05) in GP-INT cows compared to GP-CONT but not control cows. The yield of fat corrected milk was greater in CTR cows than in GP supplemented cows (P=0.01). The milk protein and fat content were greater for GP-CONT and CTR groups, respectively. Milk somatic cell count was decreased in GP supplemented cows than in CTR cows (64.5 vs. 365×103/mL; P=0.02).Plasma total protein concentration was greater in GP-CONT group. Insulin concentration was increased for GP-CON animals on day 5 (P<0.05). Non-esterified fatty acids and β-hydroxy butyrate as well as liver enzymes were unaltered by treatments. However insulin sensitivity index was lower in supplemented treatments with GP rather than control group (P<0.05). In conclusion, the intermittent delivery of glucogenic precursor may be recommendable in fresh cows based on DMI criteria, which warrants further studies. تفاصيل المقالة
      • حرية الوصول المقاله

        2 - Effects of Thyme Essential Oil and Disodium Fumarate Alone or in Combination on Performance, Blood Metabolites, Ruminal Fermentation and Microbial Communities in Holstein Dairy Cows
        H. Baraz H. Jahani-Azizabadi O. Azizi
        Nine Holstein dairy cows (630±50 kg) were used in a completely randomized design with repeated measures (two 21 d periods) to investigate the effects of disodium fumarate (DSF, 160 g/d), thyme essential oil (TEO, 9 mL/d) and simultaneous use of TEO and DSF (SIMTF أکثر
        Nine Holstein dairy cows (630±50 kg) were used in a completely randomized design with repeated measures (two 21 d periods) to investigate the effects of disodium fumarate (DSF, 160 g/d), thyme essential oil (TEO, 9 mL/d) and simultaneous use of TEO and DSF (SIMTF, 160 g/d DSF and 9 mL/d TEO) on performance, apparent digestibility, blood metabolites, rumen microbial communities and fermentation characteristics. Dry matter intake and apparent digestibility (except for TEO), milk production and composition were not affected by the treatments. Relative to the control (CON, no additive), organic matter apparent digestibility tended to decrease by TEO supplementation (578 vs. 599 g/kg). Serum urea nitrogen concentration was lower in TEO than CON (9.8 vs. 10.9 mg/dL). Also, DSF supplementation significantly increased the molar proportion of propionate and the glucogenic: non-glucogenic ratio of volatile fatty acids (VFA) and decreased the molar proportion of butyrate. Supplementation of DSF and SIMTF resulted in a significantly decrease in the acetate: propionate ratio. Relative to the CON, DSF and SIMTF supplementation significantly increased serum glucose concentration. TEO supplementation decreased rumen fluid ammonia nitrogen and increased large peptides and small peptides plus amino acid nitrogen concentration. Rumen total and cellulolytic bacteria and protozoa abundance were not affected by treatments (except for total bacteria that decreased by TEO). Results of the present study demonstrated that the simultaneous use of DSF and TEO relative to DSF alone could not have synergistic effects on performance, ruminal fermentation and serum metabolites of dairy cow. DSF can be used as a ruminal glucogenic precursor and resulted in an increase in the serum concentration of glucose in dairy cows. تفاصيل المقالة