فهرس المقالات TLR4

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  1 - Expression of Toll-Like Receptor4 (TLR4) in Pancreas of Obese Chicken
  S.K. Pathak P. Suvaneeth E. Raja Ravi Teja
  Present study tried to explore the expression of TLR4 in different parts of pancreas in relation to obesity. Broiler chicken of slaughter age (42±2 days) were selected for the study (n=30). The birds were grouped into two categories based on their body weight. Gr أکثر

  Present study tried to explore the expression of TLR4 in different parts of pancreas in relation to obesity. Broiler chicken of slaughter age (42±2 days) were selected for the study (n=30). The birds were grouped into two categories based on their body weight. Group I included birds of ≤ 1.7 kg (n=15), and group II contained birds weighing > 1.7 kg (n=15). Abdominal fat content and distribution was taken in all groups. Representative samples from dorsal, ventral and splenic lobes of pancreas were subjected to histopathology and immunohistochemistry. Obese birds showed a higher proportion of fat deposits mainly at the caudal part of abdominal cavity. The pancreatic cells in normal as well as in obese birds were devoid of any signs of cellularity, hypo/hyperplasia, degeneration and inflammation. TLR4 was detected in all three lobes of pancreas and both exocrine and endocrine parts of pancreas in all obese birds. Our results indicated that there is a direct link between obesity or visceral fat deposition and expression of TLR4 in birds. تفاصيل المقالة