فهرس المقالات BNP

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  1 - The effect of single bout of circuit resistance training on NT-proBNP levels in sedentary men
  Saeid Naraghi Mohammad Ghassami
  Introduction: Cardiac natriuretic peptides (NPs) play an important role in the regulation of energy expenditure in skeletal muscle and adipose tissue. A systematic review on the effects of exercise on NPs in patients with heart failure reported that aerobic and resistan أکثر

  Introduction: Cardiac natriuretic peptides (NPs) play an important role in the regulation of energy expenditure in skeletal muscle and adipose tissue. A systematic review on the effects of exercise on NPs in patients with heart failure reported that aerobic and resistance training reduced NPs; however, the effects of exercise on NPs and the underlying mechanism of exercise-induced NP secretion in sedentary subjects remain unknown. The aim of this study was to determine the effect of a single bout of circuit resistance training on aminoterminal propeptide (NT-proBNP) levels in sedentary men. Material & Methods: In this study, Fifteen healthy male (aged: 24.5 ± 1.2 years; ± SD) volunteered to participate in this study. The subjects were performed circuit resistance training consisted of 8 stations in the following order: chest press, barbell shoulder press, seated cable rows, barbell curl, overhead triceps extension, curl up, squat and hamstring with machine. This training was circularly performed in 8 stations and included 4 sets with 6 maximal repetitions at 70% of 1-RM in each station. Each circuit and set was separated by 5 min and 30 s rest respectively. NT-proBNP plasma concentrations were measured before and immediately after the resistance training. Paired-sample t- test was used to analyze the data. Results: The results demonstrated that NT-proBNP levels were increased significantly after the circuit resistance training (27.76% and P=0.01). Conclusions: In conclusion, a single bout of circuit resistance training in sedentary men led to a fast rise of plasma NT-proBNP concentrations. تفاصيل المقالة
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  2 - The effect of an exhaustive aerobic exercise on NT-proBNP levels in healthy males
  Mohammad Ghassami Saeid Naraghi
  Introduction: Many studies documented the relationship between elevated plasma concentrations of brain natriuretic peptide (BNP) and its aminoterminal propeptide (NT-proBNP) and cardiovascular diseases, especially heart failure (HF). However, it is still uncertain wheth أکثر

  Introduction: Many studies documented the relationship between elevated plasma concentrations of brain natriuretic peptide (BNP) and its aminoterminal propeptide (NT-proBNP) and cardiovascular diseases, especially heart failure (HF). However, it is still uncertain whether physical exercise leads to a significant release of NT-proBNP in healthy subjects. The aim of this study was to determine the effect of an exhaustive aerobic exercise on NT-proBNP levels in healthy males. Material & Methods: In this study, Fifteen healthy male (aged: 22.2 ± 2.3 years; ± SD) volunteered to participate in this study. The subjects were performed Bruce protocol as the exhaustive aerobic exercise. NT-proBNP plasma concentrations were measured before and immediately after the exhaustive aerobic exercise. Paired-sample t- test was used to analyze the data. Results: The results demonstrated that NT-proBNP levels were increased significantly after the exhaustive aerobic exercise (P<0.05). We did not find any correlation between the post-exercise increase of NT-proBNP levels and body mass index (BMI), body fat percentage (%BF) or VO2max. Conclusions: In conclusion, the exhaustive aerobic exercise in healthy individuals led to a fast rise of plasma NT-proBNP concentrations. تفاصيل المقالة
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  3 - The effect of an exhausting aerobic exercise session on plasma NT-proBNP and galectine-3 levels in male runners
  Saeed Ilbeigi Hossein Saeedi Mohammad Esmaeil Afzalpour Asghar Haghighi Maryam Heidarian Mostafa Haghighi Masoud Nadrian Jahromi
  Introduction: Brain natriuretic peptide (BNP) is an indicator released by the effect of increased intra-ventricular pressure and increased volume of ventricular myocarditis. Galectin-3 is a protein produced by the production of myocardial macrophages. The purpose of thi أکثر

  Introduction: Brain natriuretic peptide (BNP) is an indicator released by the effect of increased intra-ventricular pressure and increased volume of ventricular myocarditis. Galectin-3 is a protein produced by the production of myocardial macrophages. The purpose of this study was to investigate the effect of an exhaustive aerobic exercise session on plasma NT-proBNP and galectine-3 levels in male runners. Material & Methods: A total of 12 semi-professional male runners were selected as the subject. The Bruce test protocol was used to achieve the exhaustion. The blood sample was taken before and immediately after the completion of the exhaustive endurance exercise. Results: The results indicated that galectin-3 was increased after the exhaustive endurance exercise (P<0.05); however for NT-pro BNP no significant change was observed. Conclusions: Generally, the acute effect of exhaustive aerobic exercise on cardiac muscle function and the secretion of NT-pro BNP and galectin-3 seem to be different. It seems that galectin-3 has a higher sensitivity. However, more research is needed in this regard. تفاصيل المقالة
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  4 - The Influence of Overt Hyperthyroidism on the Plasma Level of β- type Natriuretic Peptide
  Ruqaya M. Al-sultan Hazim A. Mohammed
  10.22034/jchr.2021.684439
  Thyroid hormones (THs) have different effects on the heart and peripheral vascular system. Several changes occur across different status of thyroid dysfunctions. Overt hyperthyroidism (OHyper) induces significant changes in cardiac functions. Untreated OHyper is a cause أکثر

  Thyroid hormones (THs) have different effects on the heart and peripheral vascular system. Several changes occur across different status of thyroid dysfunctions. Overt hyperthyroidism (OHyper) induces significant changes in cardiac functions. Untreated OHyper is a cause of heart failure (HF). B-type Natriuretic Peptide (BNP) synthesized primarily in the myocardium. Thus, it is recommended as a diagnostic and prognostic marker for patients with HF. The present study was conducted to measure the effects of OHyper on the BNP level. A case-control study was conducted at a private clinic; Mosul Daily Surgical Clinic, Mosul, Nineveh, Iraq. From 1st Oct., 2020 to 1st Mar., 2021. Thirty (30) apparently healthy subjects with normal thyroid functions; Euthyroid (EU) subjects regarded as control group. Another newly diagnosed thirty (30) OHyper patients were enrolled in this study after exclusion of any facts that affect BNP level as cardiac disease, hypertension, patient taking angiotensin converting enzyme inhibitor, and pregnant ladies. They were diagnosed on the basis of thyroid function tests (TFTs); Thyroid Stimulating Hormone (TSH), Free Triiodothyronine (FT3) and Free Thyroxine (FT4). Plasma level of BNP were measured in OHyper and EU subjects’ group. Plasma BNP level is higher in patients with OHyper than EU individuals with mean values of 27.40± 35.59 and 21.68± 28.57 pg ml-1, (p>0.05) respectively. Moreover, there was a positive correlation between plasma BNP and serum FT4 level in EU (r=0.31, p=0.01) and in OHyper patients (r=0.57, P=0.001). OHyper affect plasma BNP level possibly influencing the secretion of this peptide. Therefore, thyroid functions have to be considered when evaluating any high plasma BNP level. تفاصيل المقالة