Investigation of Antimicrobial and Genotoxic Effects of Fe2O3, NiO and CoO NPs Synthesized by Green Synthesis
الموضوعات : Journal of Nanoanalysis
Hayrunnisa Nadaroglu
1
(Ataturk University, Erzurum Vocational College)
Azize Alaylı
2
(2 Department of Nano-Science and Nano-Engineering, Institute of Science and Technology, Ataturk
University, 25240 Erzurum, Turkey
3 Department of Nursing, Faculty of Health Sciences, Sakarya University of Applied Sciences, 54187,
Sakarya, Turkey)
Selçuk Çeker
3
(Department of Pharmaceutical Basic Sciences, Faculty of Pharmacy, Agri İbrahim Cecen University,
04000, Agrı, Turkey)
Hatice Ogutcu
4
(Ahi Evran University, Faculty of Agriculture, Department of Field Corps, 40200 Kırsehir, Turkey)
Guleray Agar
5
(Department of Biology, Faculty of Science, Ataturk University, 25240 Erzurum, Turkey)
الکلمات المفتاحية: Green synthesis, Antimicrobial Activity, Genotoxic effect, Pathogen microorganisms, a-Fe2O3, NiO and CoO NPs,
ملخص المقالة :
It is seen that metal nanoparticles are used in many areas due to their antimicrobialeffects. For this reason, our study focused on the production of a-Fe2O3, NiOand CoO NPs of golden nanoparticles, which are easily obtained with the use ofErzincan grape extract, safe to use, environmentally friendly and cost-effective.Metal ions synthesized by the green synthesis method were characterized usingthe Scanning Electron Microscope (SEM) analysis. From the SEM diagrams ofthe synthesized nanoparticles, it was determined that the nanoparticles wereapproximately 5 to 65 nm in size. Both antimicrobial, genotoxicity and cytotoxicityeffects were investigated to determine the rates at which nanoparticles canbe used as biosafe. Synthesized a-Fe2O3, NiO and CoO NPs showed excellentantibacterial properties on pathogen bacteria against human. In addition, it wasdetermined that a-Fe2O3, NiO and CoO M-NPs showed genotoxic properties inparallel with increasing concentrations. This study, as far as we know, is the firstreport on microbial a-Fe2O3, NiO and CoO NPs and their biological propertiessynthesized by this statistical approach.
