Calcium Chloride catalyzed Intramolecular Oxa Michael addition of 2’-Hydroxychalcone to Flavanone

الموضوعات : International Journal of Heterocyclic Chemistry

Pramod Kulkarni ¹ (Department of Chemistry, Hutatma Rajguru Mahavidyalaya Rajgurunagar Pune 410505 (MS) India)

تاريخ الإرسال : 21 الجمعة , صفر, 1439 تاريخ التأكيد : 25 الأحد , جمادى الأولى, 1439 تاريخ الإصدار : 15 الأحد , رجب, 1439

الکلمات المفتاحية:

ملخص المقالة :

An efficient cyclization of 2’-hydroxychalcone to flavanone using calcium chloride as a catalyst was developed. The scope of the reaction was studied with substituted 2’-hydroxychalcone and these chalcones was converted into corresponding flavanone in good yield. The merits of this method are inexpensive and easily available catalyst, easy workup procedure, avoid use of toxic solvent.