Selective and facile Synthesis of 2-Aminothiophenes Using Na2CaP2O7 as base Nano-Catalyst
الموضوعات : International Journal of Heterocyclic ChemistryIman Khosravi 1 , Elham Rastegar 2 , Melika Eftekhar 3 , Farid Moeinpour 4
1 - Department of Chemistry, Qeshm Branch, Islamic Azad University, Qeshm, Iran.
2 - Department of Chemistry, Qeshm Branch, Islamic Azad University, Qeshm, Iran.
3 - Department of Chemistry, Qeshm Branch, Islamic Azad University, Qeshm, Iran.
4 - Department of Chemistry, Bandar Abbas Branch, Islamic Azad University, Bandar Abbas, Iran
الکلمات المفتاحية: Nanocatalyst, Gewald reaction, 2-Aminothiophenes, Na2CaP2O7,
ملخص المقالة :
In the study we reported synthesis of 2-aminothiophene derivatives in pure water using nano-structured Na2CaP2O7. Our results indicated that this heterogeneous catalyst performed good selectivity and catalytic activity in the synthesis of substituted 2- aminothiophene through Gewald reaction in water. The noticeable benefits of this procedure rely on several factors including: a simple method, mildness conditions, short time of reaction, operational simplicity and low cost.
