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  • Designed a Resonance Rayleigh Scattering (RRS) Spectroscopic Technique for the Selective Determination of Acetaminophen Drug in Human Fluid Samples by Using Chitosan-capped Gold Nanoparticles

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رقم المقالة : 708455 زيارة : 176 الصفحة: 81 - 96

نوع المخطوط: ابحاث

Designed a Resonance Rayleigh Scattering (RRS) Spectroscopic Technique for the Selective Determination of Acetaminophen Drug in Human Fluid Samples by Using Chitosan-capped Gold Nanoparticles

الموضوعات :

Kobra Moteabbed 1 , Jafar Burromandpiroze 2 , Vahid Zare- Shahabadi 3 , Soheil Sayyahi 4

1 - Department of Chemistry, Mahshahr Branch, Islamic Azad University, Mahshahr, Iran
2 - Department of Chemistry, Mahshahr Branch, Islamic Azad University, Mahshahr, Iran
3 - Department of Chemistry, Mahshahr Branch, Islamic Azad University, Mahshahr, Iran
4 - Department of Chemistry, Mahshahr Branch, Islamic Azad University, Mahshahr, Iran

تاريخ الإرسال : 06 الثلاثاء , جمادى الثانية, 1445 تاريخ التأكيد : 06 الثلاثاء , جمادى الثانية, 1445 تاريخ الإصدار : 16 الأحد , ربيع الأول, 1445

الکلمات المفتاحية:

ملخص المقالة :

The interaction of acetaminophen drug by chitosan-capped gold Nanoparticles was investigated using a resonance Rayleigh scattering (RRS) spectroscopic technique. The standard deviation of (1.1 %), and detection limit of the method (0.5 ng mL-1 in time 6 min, 325 nm) were obtained for sensor level response chitosan-capped AuNPs with (97%) confidence evaluated. The results indicated that this method had good selectivity in the presence of coexisting compounds. The scattering intensity (ΔIRRS) was linearly dependent on acetaminophen drug concentration over the range (0.5 to 200.0 ng mL-1) with a determination coefficient (r) of 0.998. This method could be suitably used for analysis of acetaminophen drug in pharmaceutical, human fluid, and other drugs, and hospital samples.

المصادر:


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