Application of 2-methylpyridinum p-toluenesulfonate ([2-MPy][p-TSA]) as an efficient catalyst for the one-pot synthesis of hexahydroquinolines-3-carboxamides
الموضوعات :
Matin Asadi
1
(Department of Chemistry, Rasht Branch, Islamic Azad University, Rasht, Iran)
Masoud Mokhtary
2
(Department of Chemistry, Rasht Branch, Islamic Azad University, Rasht, Iran)
الکلمات المفتاحية:
ملخص المقالة :
2-Methylpyridinum p-toluenesulfonate ([2-MPy][p-TSA]) as a novel room temperature ionic liquidwas synthesized and evaluated as a recoverable catalyst for the one-pot synthesis ofhexahydroquinoline-3-carboxamide derivatives by four-component reaction of arylaldehydes,dimedone, acetoacetanilide and ammonium acetate in high to excellent yield in ethanol at 50 oC.The [2-MPy][p-TSA] catalyst was characterized via FT-IR, 1H NMR and 13C NMR spectroscopy.An environmentally benign procedure, four-component in one pot reaction, high yields and simplepreparation of the catalyst are some advantages of this work.
