Mefenamic acid as Environmentally Catalyst for Threecomponent Synthesis of Dihydropyrano [2,3-c]Chromene and Pyrano[2,3-d]Pyrimidine Derivatives

الموضوعات :

Soheila Asadpour Behzadi ¹ , Enayatollah Sheikhhosseini ² , Sayed Ali Ahmadi ³ , Dadkhoda Ghazanfari ⁴ , Mohammadreza Akhgar ⁵

1 - Department of Chemistry, Kerman Branch, Islamic Azad University, Kerman, Iran.
2 - Department of Chemistry, Kerman Branch, Islamic Azad University, Kerman, Iran.
3 - Department of Chemistry, Kerman Branch, Islamic Azad University, Kerman, Iran.
4 - Department of Chemistry, Kerman Branch, Islamic Azad University, Kerman, Iran.
5 - Department of Chemistry, Kerman Branch, Islamic Azad University, Kerman, Iran.

تاريخ الإرسال : 04 الأربعاء , شوال, 1441 تاريخ التأكيد : 04 الأربعاء , شوال, 1441 تاريخ الإصدار : 10 الأربعاء , ذو القعدة, 1441

الکلمات المفتاحية:

ملخص المقالة :

Pills of Mefenamic acid were employed as effective catalysts in the three component reaction of aromatic aldehydes, malononitrile, as well as 4-hydroxycoumarin or barbituric acid in aqueous solution, using reflux conditions in order to synthesize derivatives of dihydropyrano[2,3-c]chromene and pyrano[2,3-d]pyrimidine, correspondingly. Among the benefits of this technique, higher efficiency, shorter reaction time, along with better reaction indices could be mentioned.