Synthesis of Some Nitrogen Functional Derivatives of 5-substituted-6-azauracil as Biologically Active Compounds

الموضوعات :

Hassan Kabirifard ¹ , Zeinab Alimardani ² , Natasha Ataeimehr ³ , Gisa Rezai ⁴

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تاريخ الإرسال : 04 الإثنين , صفر, 1437 تاريخ التأكيد : 04 الإثنين , صفر, 1437 تاريخ الإصدار : 19 الثلاثاء , صفر, 1434

الکلمات المفتاحية:

ملخص المقالة :

3-Arylhydrazono-2,4-dioxo-4-phenylbutanoates have been prepared by the coupling of benzoylpyruvate with aryldiazonium chlorides. Reactions of the 3-arylhydrazono-2,4- dioxo-4-phenylbutanoates with 1-aminoguanidine, semicarbazide, and thiosemicarbazide gave 5-substituted 2-imino-6-azauracil (3a), 6-azauracil (3b), and 2-thio-6-azauracil (3c), respectively. The analytical data of these compounds - IR, 1 H, and 13C NMR spectral data - are reported.