Green Synthesis of N-pyrroles in Water via Using ZrOCl2.8H2O as an Efficient and Eco-Friendly Catalyst

الموضوعات :

Hossein Ghafuri ¹ , Atefeh Emami ²

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تاريخ الإرسال : 28 الثلاثاء , محرم, 1437 تاريخ التأكيد : 28 الثلاثاء , محرم, 1437 تاريخ الإصدار : 14 الأربعاء , رمضان, 1436

الکلمات المفتاحية:

ملخص المقالة :

A simple and efficient protocol for the synthesis of N-substituted pyrroles from one-pot condensation reaction of 2, 5-dimethoxytetrahydrofuran with aryl/alkyl, sulfonyl and acyl amines in the presence of ZrOCl2•8H2O in water has been developed. This new method has the advantages of simple experimental and work-up procedure, high to excellent yields, easy availability, economical, eco-friendly of the catalyst and high catalytic activity.