Application of Green Chemistry in Synthesis of Functionalized Thiopyran viaOne-pot Multicomponent Reactions in Water

الموضوعات :

Z. Hossaini ¹ , F. Rostami-Charati ²

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تاريخ الإرسال : 05 الثلاثاء , صفر, 1437 تاريخ التأكيد : 05 الثلاثاء , صفر, 1437 تاريخ الإصدار : 10 الثلاثاء , جمادى الثانية, 1433

الکلمات المفتاحية:

ملخص المقالة :

An efficient synthesis of 2H-thiopyran-3,4-dicarboxylate derivatives via one-pot reactions between acetylenic esters, arylisothiocyanates and enaminones in water is described.The advantages of this work were: (1) the reaction was performed under neutral and more important in water as the solvent. (2) No catalyst was required for this reaction. (3) The simplicity of the present procedure made it an interesting alternative to the complex multistep approaches.