Application of Green Chemistry in the Synthesis of Thiopyran Derivatives
الموضوعات :
Fatemeh Sheikholeslami-Farahani
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الکلمات المفتاحية:
ملخص المقالة :
An efficient synthesis of 2H-thiopyran derivatives via three-component reaction of alkyl propiolate, benzoyl isothiocyanate or its derivatives and alkyl bromides in the presence of triphenylphosphine in water at 80o C without using any catalyst in water is described. The method offers several advantages including high yields of products and an easy work-up procedure.
