Structure Exploring, IR and UV Spectroscopic Properties of Pomalidomide as a Second-generation of Immunomodulatory Agent

الموضوعات :

Reza Ghiasi ¹ (Department of Chemistry, Faculty of science, East Tehran branch, Islamic Azad University, Qiam Dasht, Tehran, Iran)
Rahimeh Rasouli ² (Department of Medical Nanotechnology, International Campus, Tehran University of Medical Sciences, Tehran, Iran)
Fatemeh Ebrahimi Shaghaghi ³ (Department of Biology, Scienceand Research Branch, Islamic Azad University, Tehran, Iran)
Farzaaneh Zaarei ⁴ (Department of Pharmaceutics,Faculty of Pharmacy,Tehran Universityof Medical Scienses,Tehran, Iran)

تاريخ الإرسال : 03 الأربعاء , ذو القعدة, 1438 تاريخ التأكيد : 03 الأربعاء , ذو القعدة, 1438 تاريخ الإصدار : 05 الإثنين , شعبان, 1438

الکلمات المفتاحية:

ملخص المقالة :

In this article, the optimized geometry, IR and UV spectra, frontier orbital analysis, natural bond orbital (NBO) analyses, and thermodynamic parameters of pomalidomide were investigated. The calculated structural parameters and stretching frequencies values are compared with experimentalvalues of the investigated compound. Also, the relations of the thermodynamic functions vs.temperatures were fitted by quadratic formulas.