Synthesis and Applicationof New Fluorescein Analogues

الموضوعات :

N. Zabarjad Shiraz ¹ , M. Bayat ² , Gh. Zarrinzadeh ³ , E. S. Shrarifzadeh ⁴

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تاريخ الإرسال : 05 الثلاثاء , صفر, 1437 تاريخ التأكيد : 05 الثلاثاء , صفر, 1437 تاريخ الإصدار : 10 الثلاثاء , جمادى الثانية, 1433

الکلمات المفتاحية:

ملخص المقالة :

In this project, new derivatives of fluorescein were synthesized using the reaction of maleic anhydride and saccharin with phenol derivatives in the presence of ZnCl2, and their structures were elucidated by UV, IR, and NMR spectroscopy. Fluorimetry studies showed that, the synthesized compounds can be utilized as fluorescent agents, and their efficiencies were dependent on pH of solution. According to the results of HF/6-31+G*//HF/STO-3G calculations as well as experimental studies, the efficiency of fluorescein analogues derived from saccharin was less than the corresponding fluorescein.