Three-component Process for the Synthesis of Some Thiophene Derivatives Using Water as a Green Media

الموضوعات :

Ali Varasteh Moradi ¹ (Department of Chemistry, Gorgan Branch, Islamic Azad University, Gorgan, Iran.)

تاريخ الإرسال : 03 الأربعاء , ذو القعدة, 1438 تاريخ التأكيد : 03 الأربعاء , ذو القعدة, 1438 تاريخ الإصدار : 05 الإثنين , شعبان, 1438

الکلمات المفتاحية:

ملخص المقالة :

A convenient and efficient three-component reaction to a one-pot synthesis of thiophene derivatives from activated acetylenic compounds and ethyl 2chloroacetoacetate in the presence of tetramethyl thiourea in water lead to the formation of thiophenes in good yields.