Application of Water for Synthesis of Cyclopentadienes via Multi-component Reactions of N-methyl imidazole

الموضوعات :

Alireza Ahmadi Agh Mashhadi ¹ , Zinatossadat Hossaini ²

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تاريخ الإرسال : 17 الإثنين , ربيع الأول, 1437 تاريخ التأكيد : 17 الإثنين , ربيع الأول, 1437 تاريخ الإصدار : 21 الجمعة , ربيع الأول, 1437

الکلمات المفتاحية:

ملخص المقالة :

A water-accelerated multi-component synthesis of organic target molecules was used as a key method for the preparation of cyclopentadiene derivatives. The three-component condensation reactions of primary amines with alkyl propiolates in the presence of N-methylimidazole in water at room temperature were developed as efficient and clean green synthetic procedures for the high-yielding preparation of 4-oxo-2,5-cyclopentadiene-1,2-dicarboxylate derivatives.