The Influences of a Dietary Phytobiotic “Yucca schidigera” Supplementation on Poultry: An Updated Article Review
الموضوعات :
1 - Department of Poultry Diseases, Faculty of Veterinary Medicine, Cairo University, Giza 12211, Egypt
الکلمات المفتاحية: antioxidant, blood metabolites, immunity, intestinal health, performance, poul-try, Yucca schidigera,
ملخص المقالة :
Over the last decade, antimicrobials have been banned as growth promoters and replaced by other natural alternatives. Plant-based poultry feed additives and herbal extracts have been effectively used in poultry worldwide. One of these feed additive phytogenic substances is Yucca schidigera (YS), which showed vari-ous beneficial effects in livestock production, including poultry. This article provides a comprehensive un-derstanding of YS’s overall benefits. The various influences of YS supplementation on performance pa-rameters of broilers, layers, and breeders, as well as carcass traits, intestinal health, immunity, and blood metabolites, and its properties as an antioxidant, anti-inflammatory, and anti-stress agent in poultry, were reviewed and updated. The dietary supplementation of YS in broilers could improve the feed intake, body weight, feed conversion ratio, as well as dressing and carcass percentage and weight. In layers and breeders, YS could enhance the egg production parameters, fertility, and hatchability, respectively. An enhanced in-testinal integrity, a decreased pathogenic bacterial load, and an increased beneficial bacterial count were observed after adding YS to the diets of different poultry species. Moreover, YS showed boosting of the bird’s humoral immune response and stimulation of the important liver and kidney metabolites. Besides, it acts as an effective antioxidant, anti-inflammatory, and anti-stress dietary supplement for poultry produc-tion systems. In conclusion, dietary YS is the best option for the overall poultry production parameters and can be used as a good natural growth-promoting antimicrobial alternative.
المصادر:
Abbas G., Rauf K. and Mahmood W. (2014). Saponins: The phy-tochemical with an emerging potential for curing clinical de-pression. Nat. Prod. Res. 29(4), 302-307.
Abd El-Ghany W.A. (2020a). A review on the use of Azolla spe-cies in poultry production. J. World’s Poult. Res. 10(2), 378-384.
Abd El-Ghany W.A. (2020b). Microalgae in poultry field: A com-prehensive perspectives. Adv. Anim. Vet. Sci. 8(9), 888-897.
Abd El-Ghany W.A. (2022). The potential uses of silymarin, a milk thistle (Silybum marianum) derivative, in poultry produc-tion system. Online J. Anim. Feed Res. 12(1), 46-52.
Abd El-Ghany W.A. (2024). The influence of the phytobiotic tulsi (Ocimum sanctum) on broiler production and health. Vet. Stanica. 55(2), 221-230.
Abd El-Ghany W.A. (2025). The different influences of a phyto-biotic, green tea (Camellia sinensis L.) on the poultry health and production. J. Appl. Vet. Sci. 10(1), 32-45.
Abd El-Ghany W.A. and Babazadeh D. (2022). Betaine: A poten-tial nutritional metabolite in the poultry industry. Animals. 12(19), 2624-2635.
Abd El-Ghany W.A. and Eraky R.D. (2019). Influence of dietary Moringa oleifera on broilers performance, intestinal microbial population and humoral immune competence. J. Hellenic Vet. Med. Soci. 70(4), 1805-1810.
Abd Elmoteleb A.M., Hafez A.S. and Ahmed H.M. (2024). Effect of Yucca Schidigera extract on Salmonella enteritidis-infected poultry compared with fosfomycin drug. Egyptian J. Vet. Sci. 1, 1-10.
Abdel-Tawwab M., Mounes H.A., Shady S.H. and Ahmed K.M. (2021). Effects of yucca, Yucca schidigera extract and/or yeast Saccharomyces cerevisiae as water additives on growth, bio-chemical and antioxidants/oxidant biomarkers of Niletilapia, Oreochromis niloticus. Aquaculture. 533, 736122-736129.
Alagawany M., Abd El-Hack M.E. and El-Kholy M.S. (2016). Productive performance, egg quality, blood constituents, im-mune functions, and antioxidant parameters in laying hens fed diets with different levels of Yucca schidigera extract. Envi-ron. Sci. Pollut. Res. 23(7), 6774-6782.
Alagawany M., Abd El-Hack M.E., Farag M.R., Elnesr S.S., El-Kholy M.S., Saadeldin I.M. and Swelum, A.A. (2018). Dietary supplementation of Yucca schidigera extract enhances produc-tive and reproductive performances, blood profile, immune function, and antioxidant status in laying Japanese quails ex-posed to lead in the diet. Poult. Sci. 97(9), 3126-3137.
Alfaro D.M., Silva A.V.F., Borges S.A., Maiorka F.A., Vargas S. and Santin E. (2007). Use of Yucca schidigera extract in broiler diets and its effects on performance results obtained with different coccidiosis control methods. J. Appl. Poult. Res. 16(2), 248-254.
Alfredo J. (2023). Quillaja saponaria and Yucca schidigera: Growth performance and nutrient digestibility in broilers. Vi-tam. Miner. 12, 256-266.
Al-Fehaid M.F., Fathi M.M., Al-Homidan I.H. and Abou-Emera O.K. (2022). Effect of yucca (Yucca Shidigera) extract sup-plementation on egg production, egg quality and immune re-sponse of laying hens. Egyptian Poult. Sci. 42(4), 483-500.
Alghirani M.M., Chung E.L.T., Sabri D.S.M., Tahir M.N.J.M., Kassim N.A., Kamalludin M.H., Nayan N., Jesse F.F.A., Sa-zili, A.Q. and Loh T.C. (2021). Can Yucca schidigera be used to enhance the growth performance, nutrient digestibility, gut histomorphology, cecal microflora, carcass characteristic, and meat quality of commercial broilers raised under tropical con-ditions? Animals. 11(8), 2276-2285.
Amirbeik E., Hassanabadi A. and Nassiri Moghaddam H. (2018). The effect of different dietary levels of Yucca schidigera ex-tract powder on performance, blood metabolites, immune sys-tem and carcass traits of broiler chickens. Iranian J. Anim. Sci. Res. 10(1), 69-80.
Aratani Y. (2018). Myeloperoxidase: its role for host defense, inflammation, and neutrophil function. Arch. Biochem. Bio-phys. 640, 47-52.
Ashour E.A., Alagawany M., Reda F.M. and Abd El-Hac M.E. (2014). Effect of supplementation of Yucca schidigera extract to growing rabbit diets on growth performance, carcass char-acteristics, serum biochemistry and liver oxidative status. Asian J. Anim. Vet. Adv. 9(11), 732-742.
Attallah N.G., El-Sherbeni S.A., El-Kadem A.H., Elekhnawy E., El-Masry T.A., Elmongy E.I., Altwaijry N. and Negm W.A. (2022). Elucidation of the metabolite profile of Yucca gigan-tea and assessment of its cytotoxic, antimicrobial, and anti-inflammatory activities. Molecules. 27(4), 1329-1335.
Awad A.L., Fahim H.N. and El-shhat A.G. (2021). Effect of add-ing Yucca schidigera powder to domyati ducklings diets on some productive characteristics and economic efficiency dur-ing summer season. Egyptian Poult. Sci. J. 41(2), 265-278.
Ayasan T. (2013). Effects of dietary Yucca schidigera on hatcha-bility of Japanese quails. Indian J. Anim. Sci. 83(6), 641-644.
Ayasan T., Yurtseven S., Baylan M. and Canogullari S. (2005). The effects of dietary Yucca shidigera on egg yield parameters and egg shell quality of laying Japanese quails (Coturnix co-turnix japonica). Int. J. Poult. Sci. 4(3), 159-162.
Ayoub M.M., Ahmed H.A., Sadek K.M., Alagawany M., Abd El-Hack M.E., Othman S.I., Allam A.A. and Abdel-Latif M.A. (2019). Effects of liquid yucca supplementation on nitrogen excretion, intestinal bacteria, biochemical and performance pa-rameters in broilers. Animals. 9(12), 1097-1103.
Bafundo K.W., Johnson A.B. and Mathis G.F. (2020). The effects of a combination of Quillaja saponaria and Yucca schidigera on Eimeria Spp. in broiler chickens. Avian Dis. 64(3), 300-304.
Bafundo K.W., Männer K. and Duerr I. (2021). The combination of quillaja and yucca saponins in broilers: Effects on perform-ance, nutrient digestibility and ileal morphometrics. Br. Poult. Sci. 62(4), 589-595.
Baker D.H. (1997). Ideal amino acid profiles for swine and poul-try and their applications in feed formulation. BioKyowa Tech. Rev. 9, 1-19.
Begum M., Hossain M.M. and Kim I.H. (2015). Effects of caprylic acid and Yucca schidigera extract on growth perform-ance, relative organ weight, breast meat quality, haematologi-cal characteristics and caecal microbial shedding in mixed sex Ross 308 broiler chickens. Vet. Med. Czech Acad. Agric. Sci. 60(11), 635-643.
Benamirouche K., Baazize-Ammi D., Hezil N., Djezzar R., Niar A. and Guetarni D. (2020). Effect of probiotics and Yucca schidigera extract supplementation on broiler meat quality. Acta Sci. Anim. Sci. 42, 48066-48076.
Bhat K.P. and Pezzuto J.M. (2002). Cancer chemopreventive ac-tivity of resveratrol. Ann. NY. Acad. Sci. 957(1), 210-229.
Bidinotto L.T., Costa C.A., Salvadori D.M., Costa M., Rodrigues M.A. and Barbisan L.F. (2011). Protective effects of lemon-grass (Cymbopogon citratus STAPF) essential oil on DNA damage and carcinogenesis in female Balb/C mice. J. Appl. Toxicol. 31(6), 536-544.
Cabuk M., Alcicek A., Bozkurt M. and Akkan S. (2004). Effect of Yucca schidigera and natural zeolite on broiler performance. J. Poult. Sci. Int. 3(10), 651-654.
Cheeke P.R. (2000). Actual and potential applications of Yucca schidigera and Quillaja saponaria saponins in human and animal nutrition. J. Anim. Sci. 77, 1-10.
Cheeke P.R. and Otero R. (2005). Yucca, quillaja may have role in animal nutrition. Feedstuffs. 77, 11-14.
Cheeke P.R., Piacente S. and Oleszek W. (2006). Anti-inflammatory and anti-arthritic effects of Yucca schidigera: A review. J. Inflamm. 3, 6-15.
Chen D. and Yu B. (2020). Animal Nutrition. China Agriculture Press, Beijing, China.
Chepete H.J., Xin H., Mendes L.B., Li H. and Bailey T.B. (2012). Ammonia emission and performance of laying hens as af-fected by different dosages of Yucca schidigera in the diet. J. Appl. Poult. Res. 21(3), 522-530.
Cheung K.L., Lee J.H., Khor T.O., Wu T.Y., Li G.X., Chan J., Yang C.S. and Kong A.N.T. (2014). Nrf2 knockout en-hances intestinal tumorigenesis in Apc (min/+) mice due to at-tenuation of anti-oxidative stress pathway while potentiates in-flammation. Mol. Carcinog. 53(1), 77-84.
Chrenková M., Chrenková M., Poláĉiková M., Formelová Z., Baláži A., Ondruška Ľ., Sirotkin A. and Chrenek P. (2012). The effect of Yucca schidigera extract in diet of rabbits on nu-trient digestibility and qualitative parameters in caecum. Slo-vak. J. Anim. Sci. 45(3), 83-88.
Dai Z., Wang H., Liu J., Zhang H., Li Q., Yu X., Zhang R. and Yang C. (2023). Comparison of the Effects of Yucca saponin, Yucca schidigera, and Quillaja saponaria on growth perform-ance, immunity, antioxidant capability, and intestinal flora in broilers. Animals. 13(9), 1447-1456.
Das T.K., Banerjee D., Chakraborty D., Pakhira M.C., Shrivastava B. and Kuhad C. (2012). Saponin: Role in animal system. Vet. World. 5(4), 248-254.
Demain A.L. and Sanchez S. (2009). Microbial drug discovery: 80 years of progress. J. Antibiotics (Tokyo). 62(1), 5-16.
Dengsheng S., Xiao J., Binlin S., Junling S., Manman T. and Sumei Y. (2017). Dietary Yucca schidigera extract improved growth performance and liver antioxidative function in broil-ers. Italian J. Anim. Sci. 16(4), 677-684.
Dolla A., Fournier M. and Dermoun Z. (2006). Oxygen defense in sulfate-reducing bacteria. J. Biotechnol. 126(1), 87-100.
Dziuk H.E., Duke G.E., Buck R.J. and Janni K.A. (1985). Diges-tive parameters in young turkeys fed yucca saponin. Poult. Sci. 64(6), 1143-1147.
Ebru O.E., Erdem E., Afsinya N.U. and Torlak E. (2013). Effect of Yucca schidigera spraying in different litter materials on some litter traits and breast burn of broilers at the fifth week of production. Kaf. Univ. Vet. Fak. Derg. 19(5), 749-753.
Elmeligy E.H., Attallah S.T., Sallam E.A. and Mohammed L.S. (2025). Impact of Yucca extract and basil oil supplementation on carcass characteristics, quality of meat, and the cecal mi-crobiota in broiler chickens. J. Adv. Vet. Res. 15(1), 20-27.
El-Sawah A.A., Aboelhadid S.M., El-Nahass E.N. and Helal H.E. (2025). Efficacy of nanoemulsion of Yucca shidigera extract in controlling Eimeria tenella infection in broilers. Assiut Vet. Med. J. 71(185), 65-82.
EL-Shafei A.A., AL-Gamal M.A. and Shams El-deen A.E. (2022). Effectiveness of caprylic acid and Yucca schidigera extract on productive and physiological performance of laying hens. Egyptian J. Nutr. Feeds. 25(1), 67-83.
Enaiat M.M.E., Eman M., Abou-Eitta A., Salem A. and Al-Kotait A.H.A. (2009). Effect of Yucca schidigera extract and alumi-num chloride on pen’s atmospheric ammonia, productive, re-productive and physiology performance of silver montazah cocks. Egyptian J. Poult. Sci. 29, 337-356.
Enginar H., Avci G., Eryavuz A., Kaya E., Kucukkurt I. and Fidan A.F. (2006). Effect of Yucca schidigera extract on lipid per-oxidation and antioxidant activity in rabbits exposed to γ ra-diation. Rev. Méd. Vét. 157(8), 415-419.
Farag M.R., Alagawany M., EI-Hack M.E.A., EI-Sayed S.A.A., Ahmed S.Y.A. and Samak D.H. (2018). Yucca schidigera ex-tract modulates the lead-induced oxidative damage, nephropa-thy and altered inflammatory response and glucose homeosta-sis in Japanese quails. Ecotoxicol. Environ. Saf. 156, 311-321.
Franchis G., Kerem Z., Makkar H.P.S. and Becker K. (2002). The biological action of saponins in animal systems: A review. Br. J. Nutr. 88(6), 587-605.
Gaber M.M. (2006). The effects of plant-protein based diets sup-plemented with Yucca on growth, digestibility, and chemical composition of Nile Tilapia (Oreochromis niloticus) inger-lings. J. World Aquac. Soci. 37(1), 74-81.
Galli G.M., Da Silva A.S., Bottari N.B., Biazus A.H., Petrolli T., Reis J.H., Morsch V.M., Schetinger M.R.C., Piva M.M., Bag-gio R.A., Mendes R.E., Boiago M.M., Stefani L.M. and Machado G. (2018). Addition of yucca extract and glutamine in the diet of chicks had a protective effect against coccidiosis. Comp. Clin. Pathol. 27(1), 205-214.
Galli G.M., Griss L.G., Boiago M.M., Petrolli T.G., Glombowsky P., Bissacotti B.F., Copetti P.M., da Silva A.D., Schetinger M.R., Sareta L., Mendes R.E., Mesadri J., Wagner R., Gundel S., Ourique A.F. and Da Silva A.S. (2020). Effects of curcu-min and Yucca extract addition in feed of broilers on microor-ganism control (anticoccidial and antibacterial), health, per-formance and meat quality. Res. Vet. Sci. 132, 156-166.
Gao D., Zhao M., Qi X., Liu Y., Li N., Liu Z. and Bian Y. (2016). Hypoglycemic effect of Gynostemma pentaphyllum saponins by enhancing the Nrf2 signaling pathway in STZ-inducing diabetic rats. Arch. Pharm. Res. 39(2), 221-230.
Guclu B. (2003). The effects of Yucca schidigera extract added to quail rations on egg production, egg quality and some blood parameters. Turkish J. Vet. Anim. Sci. 27(3), 567-574.
Guclu B. and Iscan K.M. (2004). The effects of Yucca schidigera extract added to quail rations on fattening performance. J. Er-ciyes. Univ. Fac. Vet. Med. 1, 5-20.
Gupta S. (2014). Inhibitory potential of Yucca gloriosa L. extract and isolated gloriosaol isomeric mixture on ovalbumin in-duced airway hyperresponsiveness in Balb/C mice. Clin. Pharmacol. Biopharm. 2(1), 1-9.
Gurbuz E., Balevi T., Kurtoglu V. and Oznurlu Y. (2011). Effects of adding yeast cell walls and Yucca schidigera extract to diets of layer chicks. Br. Poult. Sci. 52(5), 625-631.
Gurbuz E., Balevi T., Kurtoglu V. and Oznurlu Y. (2016). Use of yeast cell walls and Yucca shidigera extract in layer hens’ di-ets. Italian J. Anim. Sci. 10(2), 26-34.
Hassan S.M., Byrd J.A., Cartwright A.L. and Bailey C.A. (2010). Haemolytic and antimicrobial activities differ among saponin-rich extracts from guar, quillaja, yucca, and soybean. Appl. Biochem. Biotechnol. 162(4), 1008-1017.
Johnston N.L., Quarles C.L., Fagerberg D.J. and Caveny D.D. (1981). Evaluation of yucca saponin on broiler performance and ammonia suppression. Poult. Sci. 60(10), 2289-2292.
Jun-Ling S., Bin-Lin S., Peng-Fei Z., Deng-Sheng S., Ti-Yu L. and Su-Mei Y. (2016). Effects of Yucca extract on feed effi-ciency, immune and antioxidative functions in broilers. Braz. Arch. Biol. Technol. 59, 1-11.
Kaya S., Erdogan Z. and Erdogan S. (2003). Effect of different dietary levels of Yucca schidigera powder on the performance, blood parameters and egg yolk cholesterol of laying quails. J. Vet. Med. A Physiol. Pathol. Clin. Med. 50(1), 14-17.
Kelly A.M. and Kohler C.C. (2003). Effects of Yucca schidigera extract on growth, nitrogen retention, ammonia excretion, and toxicity in channel catfish Ictalurus punctatus and hybrid tila-pia O. mossambicus × O. niloticus. J. World Aquac. Soci. 34(2), 156-161.
Khaskheli A.A., Khaskheli M.I. and Khaskheli A.J. (2020). Die-tary influence of Yucca schidigera on broilers and layers: A Review. Int. J. Vet. Sci. 9, 458-461.
Kim D.H., Moon Y.S., Jung J.S., Min S.K., Son B.K. and Suh H.W. (2003). Effects of ginseng saponin administered intrap-eritoneally on the hypothalamo-pituitary-adrenal axis in mice. Neurosci. Lett. 343(1), 62-65.
Kozłowski K., Vervenne-Zetteler P., Konieczka P., Szyma´ nski Ł. and van Vilsteren A. (2022). Yucca schidigera improves performance and lowers oocyst counts in Eimeria challenged broilers. Animals (Basel). 12(13), 1668-1678.
Kucukkurt I., Akkol E.K., Karabag F., Ince S., Süntar I., Eryavuz A. and Sözbilir N.B. (2016). Determination of the regulatory properties of Yucca schidigera extracts on the biochemical pa-rameters and plasma hormone levels associated with obesity. Rev. Bras. Farmacogn. 26(2), 246-250.
Kutlu H.R., Görgülü M. and Ünsal I. (2001). Effects of dietary Yucca schidigera powder on performance and egg cholesterol content of laying hens. J. Appl. Anim. Res. 20(1), 49-56.
Lan J., Wang K., Chen G., Cao G. and Yang C. (2020). Effects of inulin and isomalto oligosaccharide on diphenoxylate-induced constipation, gastrointestinal motility-related hormones, short-chain fatty acids, and the intestinal flora in rats. Food Function J. 11(10), 9216-9225.
Li W.B., Wang H.Y., Ma Y.M., Zhao X.H., Yang H., Qian J.M. and Li J.N. (2018). VSL#3 can prevent ulcerative colitis-associated carcinogenesis in mice. World J. Gastroenterol. 24(37), 4254-4262.
Liang G., Wang X., Wang X., Li C. and Chen G. (2009). Effects of camphor familial plant extract and Yucca extracts on emis-sion of NH3 and H2S in slurry of weaned pigs. Chin. J. Anim. Sci. 45, 22-26.
Lillehoj H., Liu Y., Calsamiglia S., Fernandez-Miyakawa M.E., Chi F., Cravens R.L., Oh S. and Gay C.G. (2018). Phyto-chemicals as antibiotic alternatives to promote growth and en-hance host health. Vet. Res. 49(1), 76-75.
Luo X., Zheng C., Xia W., Ruan D., Wang S., Zhang Y.N. and Chen W. (2018). Effects of constant or intermittent high tem-perature on the feed intake, hypothalamic expression of anti-oxidant and pro-oxidant enzymes genes in laying ducks. J. Anim. Sci. 96(12), 5064-5074.
Luo J.J., Chen W., Qu H., Liu Y.Q., Luo C.L., Ji J., Shu D.M. and Wang J. (2022). Dietary supplementation with Yucca allevi-ates heat stress in growing broilers exposed to high ambient temperature. Front. Vet. Sci. 9, 850715-850723.
Lundeen T. (2000). Yucca extract improves feed efficiency, de-creases abdominal fat in broilers. Feedstuffs Repr. 72, 1-9.
Malecki J.A., Ramisz L., Mardarowicz L. and Pilarczyk B. (1995). The influence of Yucca shidigera extract on environment and productivity of broilers. Zeszyty Naurokowe Akademii Rolnic-zej w. Szczecinie, Zootechnica. 32, 51-56.
Mao X., Dou Y., Fan X., Yu B., He J., Zheng P., Yu J., Luo J., Luo Y., Yan H., Wang J., Wang H. and Wang Q. (2023). The effect of dietary Yucca schidigera extract supplementation on productive performance, egg quality, and gut health in laying hens with Clostridium perfringens and coccidia challenge. Poult. Sci. 102(8), 102822-102832.
Martin-Gallausiaux C., Marinelli L., Blottière H.M., Larraufie P. and Lapaque N. (2021). SCFA: Mechanisms and functional importance in the gut. Proc. Nutr. Soc. 80(1), 37-49.
Matusiak K., Oleksy M., Borowski S., Nowak A., Korczyński M., Dobrza´nski Z. and Gutarowska B. (2016). The use of Yucca schidigera and microbial preparation for poultry manure de-odorization and hygienization. J. Environ. Manag. 170, 50-59.
McAllister T.A., Annett C.B., Cockwill C.L., Olson M.E., Wang Y. and Hahn T.W. (2001). Studies on the use of Yucca schidigera to control giardiosis. Vet. Parasitol. 97(2), 85-99.
Mert S. (2025). Effects of humate, Yucca, and humate-Yucca combination supplementation on growth performance, gut health, and immune response in broiler chickens. Front. Vet. Sci. 12, 1-11.
Munezero O., Zhang Z. and Kim I. (2023). The effects of Yucca Schidigera extract and multi-carbohydrase in different crude protein diets on growth performance, nutrient digestibility, carcass parameters and excreta noxious gas contents in broil-ers. Brazilian J. Poult. Sci. 25(1), 1-8.
Nazeer M.S., Pasha T.N., Shahid A. and Ali Z. (2002). Effect of Yucca saponin on urease activity and development of ascites in broiler chickens. Int. J. Poult. Sci. 1(6), 174-178.
Obianwuna U.E., Chang X., Oleforuh O.V.U., Onu P.N., Zhang H., Qiu K. and Wu S. (2024). Phytobiotics in poultry: Revolu-tionizing broiler chicken nutrition with plant-derived gut health enhancers. J. Anim. Sci. Biotechnol. 15, 169-175.
Oelschlager M.L., Rasheed M.S.A., Smith B.N., Rincker M.J. and Dilger R.N. (2019). Effects of Yucca schidigera derived saponin supplementation during a mixed Eimeria challenge in broilers. Poult. Sci. 98(8), 3212-3222.
Oleszek W., Sitek M., Stochmal A., Piacente S., Pizza C. and Cheeke P. (2001). Resveratrol and other phenolics from the bark of Yucca schidigera roezl. J. Agric. Food Chem. 49(2), 747-452.
Oviedo E.O., Parker J., Clack B. and Waetherford W. (2003). Concentrate Extract of Yucca schidigera (BioSupreme®) Plant as Feed Additive in Broiler Diets in the Control of Eimeria In-fection. Austin State University, Nacogdoches, TX, USA.
Patel S. (2012). Yucca: A medicinally significant genus with manifold therapeutic attributes. Nat. Prod. Bioprospect. 2(6), 231-234.
Patoary M.U., Hossain M., Akter M. and Rubel Z.U. (2020). Ef-fect of supplementation of Yucca schidigera extract on ammo-nia gas emission and performance of broiler chickens. J. World Poult. Res. 10(1), 57-62.
Pen B., Sar C., Mwenya B., Kuwaki K., Morikawa R. and Taka-hashi J. (2006). Effects of Yucca schidigera and Quillaja saponaria extracts on in vitro ruminal fermentation and meth-ane emission. Anim. Feed Sci. Technol. 129(3), 175-186.
Piacente S., Pizza C. and Oleszek W. (2005). Saponins and pheno-lics of Yucca schidigera Roezl: Chemistry and bioactivity. Phytochem. Rev. 4, 177-190.
Piacente S., Montoro P., Oleszek W. and Pizza C. (2004). Yucca schidigera bark: phenolic constituents and antioxidant activity. J. Nat. Prod. 67(5), 882-885.
Preston C.M., McCracken K.J. and Bedford M.R. (1999). Effects of Yucca schdigera extract, Saccharomyces boulardii and en-zyme supplementation of wheat-based diets on broiler per-formance and diet metabolisability. Br. Poult. Sci. 40(1), 39-40.
Rahman M.M., Begum S. and Mondol S.I.A.K. (2023). Impact of Yucca schidigera plant extract supplementation to diet on body growth, carcass characteristic’s, gut microbiota, intesti-nal ammonia concentration and hematology in broiler chick-ens. J. Sylhet Agric. Univ. 10(1), 17-22.
Ranjbar Z., Shariatmadari F. and Torshizi M.K. (2014). Effect of different levels of yucca extract and antibiotic on growth per-formance, immune response and blood factors of broiler chickens. Iranian J. Med. Aromat. Plants. 30(5), 675-681.
Rezaei R., Lei J. and Wu G. (2017). Dietary supplementation with Yucca schidigera extract alleviates heat stress–induced growth restriction in chickens. J. Anim. Sci. 95(4), 370-371.
Saddoris-Clemons K., Osho S., Garcia M. and Humphrey B. (2024). Effects of dietary inclusion of a proprietary combina-tion of Quillaja saponaria and Yucca schidigera on intestinal permeability and immune response in broiler chickens during a coccidia challenge. Animals. 14(12), 1737-1745.
Saeed M., Arain M.A., Naveed M., Alagawany M., Abd El-Hack M.E., Bhutto Z.A. and Chao S. (2018). Yucca schidigera can mitigate ammonia emissions from manure and promote poul-try health and production. Environ. Sci. Pollut. Res. Int. 25(35), 35027-35033.
Saleh A.A., Paray B.A. and Dawood M.A.O. (2020). Olive cake meal and Bacillus licheniformis impacted the growth perform-ance, muscle fatty acid content, and health status of broiler chickens. Animals. 10(4), 695-701.
Sahoo S.P., Kaur D., Sethi A.P., Sharma A. and Chandra M. (2015). Evaluation of Yucca schidigera extract as feed addi-tive on performance of broiler chicks in winter season. Vet. World. 8(4), 556-560.
Sahoo S., Kaur D., Sethi A., Saini A. and Chandra M. (2016). Effect of dietary supplementation of yucca schidigera extract on the performance and litter quality of broilers in winter sea-son. Anim. Nutr. Feed Technol. 16(3), 475-484.
Sariozkan S., Konca Y., Guclu B.K., Kara K., Ildiz N., Kirkpinar F., Beyzi S.B. and Kaliber M. (2015). Effects of dietary sup-plementation of dried distillers grain with solubles (DDGS) and yucca (Yucca schidigera) on broiler performance, carcass traits, intestinal viscosity and marketing. J. Poult. Res. 12(1), 5-11.
Sidhu G. and Oakenfull D.A. (1986). Mechanism for the hypocho-lesterolaemic activity of saponins. Br. J. Nutr. 55(3), 643-649.
Song X. and Hu S. (2009). Adjuvant activities of saponins from traditional Chinese medicinal herbs. Vaccine. 27(36), 4883-4890.
Su J.L., Shi B.L., Zhang P.F., Sun D.S., Li T.Y. and Yan S.M. (2016). Effects of Yucca extract on feed efficiency, immune and antioxidative functions in broilers. Braz. Arch. Biol. Tech-nol. 59, 1-9.
Sun D.S., Shi B.L., Tong M.M. and Yan S.M. (2017). Improved performance and immunological responses as a result of die-tary Yucca schidigera extract supplementation in broilers. Ital-ian J. Anim. Sci. 17(2), 511-517.
Sun D., Jin X., Camerlink I., Tong M., Su J., Zhao F., Yan S. and Shi B. (2019). Effects of Yucca schidigera extract on growth performance and antioxidative function of small intestine in broilers. J. Anim. Physiol. Anim. Nutr. 103(3), 738-346.
Sun X., Wang Z., Li X., Du S., Lin D. and Shao Y. (2023). Effects of Yucca schidigera extract on serum biochemical parameters, humoral immune response, and intestinal health in young pi-geons. Front. Vet. Sci. 9, 77555-77564.
Trejo Castro L. (2002). Report of the Evaluation of Effectiveness of the Product Yucca schidigera as Anticoccidial in Broiler Feed; LAB.PAR.IND2001 003; Baja Agro International, En-senada, Mexico.
Tsukahara T. and Ushida K. (2000). Effects of animal or plant protein diets on cecal fermentation in Guinea pigs (Cavia por-cellus), rats (Rattus norvegicus) and chicks (Gallus gallus do-mesticus). Comp. Biochem. Physiol. A Mol. Integr. Physiol. 127(2), 139-146.
Tugay A., Yurtseven S., Baylan M. and Canogullari S. (2005). The effects of dietary Yucca shidigera on egg yield parameters and egg shell quality of laying hens. Int. J. Poult. Sci. 4, 159-162.
Vlčková R., Sopková D., Andrejčáková Z., Valocký I., Kádasi A., Harrath A.H., Petrilla V. and Sirotkin A.V. (2017). Dietary supplementation of yucca (Yucca schidigera) affects ovine ovarian functions. Theriogenology. 88, 158-165.
Wang Y., Mcallister T.A., Newbold C.J., Rode L.M., Cheeke P.R. and Cheng K.J. (1998). Effects of Yucca schidigera extract on fermentation and degradation of steroidal saponins in the ru-men simulation technique (RUSITEC). Anim. Feed Sci. Tech-nol. 74(2), 143-153.
Wang J.P. and Kim I.H. (2011). Effect of caprylic acid and Yucca schidigera extract on production performance, egg quality, blood characteristics, and excreta microflora in laying hens. Br. Poult. Sci. 52(6), 711-717.
Wang L., Wu D., Fan Z., Li H., Li J., Zhang Y., Xu Q., Wang G. and Zhu Z. (2020). Effect of Yucca schidigera extract on the growth performance, intestinal antioxidant status, immune re-sponse, and tight junctions of mirror carp (Cyprinus carpio). Fish Shellfish Immunol. 103, 211-219.
Wang Y., Zhang Y., Ren H., Fan Z., Yang X., Zhang C. and Jiang Y. (2023). Dietary Yucca extract and Clostridium butyricum promote growth performance of weaned rabbits by improving nutrient digestibility, intestinal development, and microbial composition. Front. Vet. Sci. 10, 1-8.
Yang Y., Lee J., Rhee M.H., Yu T., Baek K.S., Sung N.Y., Kim Y., Yoon K., Kim J.H., Kwak Y.S., Hong S., Kim J.H. and Cho J.Y. (2015). Molecular mechanism of protopanaxadiol saponin fraction-mediated anti-inflammatory actions. J. Gin-seng. Res. 39(1), 61-68.
Yeo J. and Kim K.I. (1997). Effect of feeding diets containing an antibiotic, a probiotic, or yucca extract on growth and intesti-nal urease activity in broiler chicks. Poult. Sci. 76(2), 381-385.
Zdanowska-Sąsiadek Z., Lipińska-Palka P., Damaziak K., Michalczuk M., Grzybek W., Kruzi´nska B., Jasi´nska K., Róg D., Kordos K. and Abek K. (2019). Antioxidant effects of phytogenic herbal-vegetable mixtures additives used in chicken feed on breast meat quality. Anim. Sci. Pap. Rep. 37(4), 393-408.
Abbas G., Rauf K. and Mahmood W. (2014). Saponins: The phy-tochemical with an emerging potential for curing clinical de-pression. Nat. Prod. Res. 29(4), 302-307.
Abd El-Ghany W.A. (2020a). A review on the use of Azolla spe-cies in poultry production. J. World’s Poult. Res. 10(2), 378-384.
Abd El-Ghany W.A. (2020b). Microalgae in poultry field: A com-prehensive perspectives. Adv. Anim. Vet. Sci. 8(9), 888-897.
Abd El-Ghany W.A. (2022). The potential uses of silymarin, a milk thistle (Silybum marianum) derivative, in poultry produc-tion system. Online J. Anim. Feed Res. 12(1), 46-52.
Abd El-Ghany W.A. (2024). The influence of the phytobiotic tulsi (Ocimum sanctum) on broiler production and health. Vet. Stanica. 55(2), 221-230.
Abd El-Ghany W.A. (2025). The different influences of a phyto-biotic, green tea (Camellia sinensis L.) on the poultry health and production. J. Appl. Vet. Sci. 10(1), 32-45.
Abd El-Ghany W.A. and Babazadeh D. (2022). Betaine: A poten-tial nutritional metabolite in the poultry industry. Animals. 12(19), 2624-2635.
Abd El-Ghany W.A. and Eraky R.D. (2019). Influence of dietary Moringa oleifera on broilers performance, intestinal microbial population and humoral immune competence. J. Hellenic Vet. Med. Soci. 70(4), 1805-1810.
Abd Elmoteleb A.M., Hafez A.S. and Ahmed H.M. (2024). Effect of Yucca Schidigera extract on Salmonella enteritidis-infected poultry compared with fosfomycin drug. Egyptian J. Vet. Sci. 1, 1-10.
Abdel-Tawwab M., Mounes H.A., Shady S.H. and Ahmed K.M. (2021). Effects of yucca, Yucca schidigera extract and/or yeast Saccharomyces cerevisiae as water additives on growth, bio-chemical and antioxidants/oxidant biomarkers of Niletilapia, Oreochromis niloticus. Aquaculture. 533, 736122-736129.
Alagawany M., Abd El-Hack M.E. and El-Kholy M.S. (2016). Productive performance, egg quality, blood constituents, im-mune functions, and antioxidant parameters in laying hens fed diets with different levels of Yucca schidigera extract. Envi-ron. Sci. Pollut. Res. 23(7), 6774-6782.
Alagawany M., Abd El-Hack M.E., Farag M.R., Elnesr S.S., El-Kholy M.S., Saadeldin I.M. and Swelum, A.A. (2018). Dietary supplementation of Yucca schidigera extract enhances produc-tive and reproductive performances, blood profile, immune function, and antioxidant status in laying Japanese quails ex-posed to lead in the diet. Poult. Sci. 97(9), 3126-3137.
Alfaro D.M., Silva A.V.F., Borges S.A., Maiorka F.A., Vargas S. and Santin E. (2007). Use of Yucca schidigera extract in broiler diets and its effects on performance results obtained with different coccidiosis control methods. J. Appl. Poult. Res. 16(2), 248-254.
Alfredo J. (2023). Quillaja saponaria and Yucca schidigera: Growth performance and nutrient digestibility in broilers. Vi-tam. Miner. 12, 256-266.
Al-Fehaid M.F., Fathi M.M., Al-Homidan I.H. and Abou-Emera O.K. (2022). Effect of yucca (Yucca Shidigera) extract sup-plementation on egg production, egg quality and immune re-sponse of laying hens. Egyptian Poult. Sci. 42(4), 483-500.
Alghirani M.M., Chung E.L.T., Sabri D.S.M., Tahir M.N.J.M., Kassim N.A., Kamalludin M.H., Nayan N., Jesse F.F.A., Sa-zili, A.Q. and Loh T.C. (2021). Can Yucca schidigera be used to enhance the growth performance, nutrient digestibility, gut histomorphology, cecal microflora, carcass characteristic, and meat quality of commercial broilers raised under tropical con-ditions? Animals. 11(8), 2276-2285.
Amirbeik E., Hassanabadi A. and Nassiri Moghaddam H. (2018). The effect of different dietary levels of Yucca schidigera ex-tract powder on performance, blood metabolites, immune sys-tem and carcass traits of broiler chickens. Iranian J. Anim. Sci. Res. 10(1), 69-80.
Aratani Y. (2018). Myeloperoxidase: its role for host defense, inflammation, and neutrophil function. Arch. Biochem. Bio-phys. 640, 47-52.
Ashour E.A., Alagawany M., Reda F.M. and Abd El-Hac M.E. (2014). Effect of supplementation of Yucca schidigera extract to growing rabbit diets on growth performance, carcass char-acteristics, serum biochemistry and liver oxidative status. Asian J. Anim. Vet. Adv. 9(11), 732-742.
Attallah N.G., El-Sherbeni S.A., El-Kadem A.H., Elekhnawy E., El-Masry T.A., Elmongy E.I., Altwaijry N. and Negm W.A. (2022). Elucidation of the metabolite profile of Yucca gigan-tea and assessment of its cytotoxic, antimicrobial, and anti-inflammatory activities. Molecules. 27(4), 1329-1335.
Awad A.L., Fahim H.N. and El-shhat A.G. (2021). Effect of add-ing Yucca schidigera powder to domyati ducklings diets on some productive characteristics and economic efficiency dur-ing summer season. Egyptian Poult. Sci. J. 41(2), 265-278.
Ayasan T. (2013). Effects of dietary Yucca schidigera on hatcha-bility of Japanese quails. Indian J. Anim. Sci. 83(6), 641-644.
Ayasan T., Yurtseven S., Baylan M. and Canogullari S. (2005). The effects of dietary Yucca shidigera on egg yield parameters and egg shell quality of laying Japanese quails (Coturnix co-turnix japonica). Int. J. Poult. Sci. 4(3), 159-162.
Ayoub M.M., Ahmed H.A., Sadek K.M., Alagawany M., Abd El-Hack M.E., Othman S.I., Allam A.A. and Abdel-Latif M.A. (2019). Effects of liquid yucca supplementation on nitrogen excretion, intestinal bacteria, biochemical and performance pa-rameters in broilers. Animals. 9(12), 1097-1103.
Bafundo K.W., Johnson A.B. and Mathis G.F. (2020). The effects of a combination of Quillaja saponaria and Yucca schidigera on Eimeria Spp. in broiler chickens. Avian Dis. 64(3), 300-304.
Bafundo K.W., Männer K. and Duerr I. (2021). The combination of quillaja and yucca saponins in broilers: Effects on perform-ance, nutrient digestibility and ileal morphometrics. Br. Poult. Sci. 62(4), 589-595.
Baker D.H. (1997). Ideal amino acid profiles for swine and poul-try and their applications in feed formulation. BioKyowa Tech. Rev. 9, 1-19.
Begum M., Hossain M.M. and Kim I.H. (2015). Effects of caprylic acid and Yucca schidigera extract on growth perform-ance, relative organ weight, breast meat quality, haematologi-cal characteristics and caecal microbial shedding in mixed sex Ross 308 broiler chickens. Vet. Med. Czech Acad. Agric. Sci. 60(11), 635-643.
Benamirouche K., Baazize-Ammi D., Hezil N., Djezzar R., Niar A. and Guetarni D. (2020). Effect of probiotics and Yucca schidigera extract supplementation on broiler meat quality. Acta Sci. Anim. Sci. 42, 48066-48076.
Bhat K.P. and Pezzuto J.M. (2002). Cancer chemopreventive ac-tivity of resveratrol. Ann. NY. Acad. Sci. 957(1), 210-229.
Bidinotto L.T., Costa C.A., Salvadori D.M., Costa M., Rodrigues M.A. and Barbisan L.F. (2011). Protective effects of lemon-grass (Cymbopogon citratus STAPF) essential oil on DNA damage and carcinogenesis in female Balb/C mice. J. Appl. Toxicol. 31(6), 536-544.
Cabuk M., Alcicek A., Bozkurt M. and Akkan S. (2004). Effect of Yucca schidigera and natural zeolite on broiler performance. J. Poult. Sci. Int. 3(10), 651-654.
Cheeke P.R. (2000). Actual and potential applications of Yucca schidigera and Quillaja saponaria saponins in human and animal nutrition. J. Anim. Sci. 77, 1-10.
Cheeke P.R. and Otero R. (2005). Yucca, quillaja may have role in animal nutrition. Feedstuffs. 77, 11-14.
Cheeke P.R., Piacente S. and Oleszek W. (2006). Anti-inflammatory and anti-arthritic effects of Yucca schidigera: A review. J. Inflamm. 3, 6-15.
Chen D. and Yu B. (2020). Animal Nutrition. China Agriculture Press, Beijing, China.
Chepete H.J., Xin H., Mendes L.B., Li H. and Bailey T.B. (2012). Ammonia emission and performance of laying hens as af-fected by different dosages of Yucca schidigera in the diet. J. Appl. Poult. Res. 21(3), 522-530.
Cheung K.L., Lee J.H., Khor T.O., Wu T.Y., Li G.X., Chan J., Yang C.S. and Kong A.N.T. (2014). Nrf2 knockout en-hances intestinal tumorigenesis in Apc (min/+) mice due to at-tenuation of anti-oxidative stress pathway while potentiates in-flammation. Mol. Carcinog. 53(1), 77-84.
Chrenková M., Chrenková M., Poláĉiková M., Formelová Z., Baláži A., Ondruška Ľ., Sirotkin A. and Chrenek P. (2012). The effect of Yucca schidigera extract in diet of rabbits on nu-trient digestibility and qualitative parameters in caecum. Slo-vak. J. Anim. Sci. 45(3), 83-88.
Dai Z., Wang H., Liu J., Zhang H., Li Q., Yu X., Zhang R. and Yang C. (2023). Comparison of the Effects of Yucca saponin, Yucca schidigera, and Quillaja saponaria on growth perform-ance, immunity, antioxidant capability, and intestinal flora in broilers. Animals. 13(9), 1447-1456.
Das T.K., Banerjee D., Chakraborty D., Pakhira M.C., Shrivastava B. and Kuhad C. (2012). Saponin: Role in animal system. Vet. World. 5(4), 248-254.
Demain A.L. and Sanchez S. (2009). Microbial drug discovery: 80 years of progress. J. Antibiotics (Tokyo). 62(1), 5-16.
Dengsheng S., Xiao J., Binlin S., Junling S., Manman T. and Sumei Y. (2017). Dietary Yucca schidigera extract improved growth performance and liver antioxidative function in broil-ers. Italian J. Anim. Sci. 16(4), 677-684.
Dolla A., Fournier M. and Dermoun Z. (2006). Oxygen defense in sulfate-reducing bacteria. J. Biotechnol. 126(1), 87-100.
Dziuk H.E., Duke G.E., Buck R.J. and Janni K.A. (1985). Diges-tive parameters in young turkeys fed yucca saponin. Poult. Sci. 64(6), 1143-1147.
Ebru O.E., Erdem E., Afsinya N.U. and Torlak E. (2013). Effect of Yucca schidigera spraying in different litter materials on some litter traits and breast burn of broilers at the fifth week of production. Kaf. Univ. Vet. Fak. Derg. 19(5), 749-753.
Elmeligy E.H., Attallah S.T., Sallam E.A. and Mohammed L.S. (2025). Impact of Yucca extract and basil oil supplementation on carcass characteristics, quality of meat, and the cecal mi-crobiota in broiler chickens. J. Adv. Vet. Res. 15(1), 20-27.
El-Sawah A.A., Aboelhadid S.M., El-Nahass E.N. and Helal H.E. (2025). Efficacy of nanoemulsion of Yucca shidigera extract in controlling Eimeria tenella infection in broilers. Assiut Vet. Med. J. 71(185), 65-82.
EL-Shafei A.A., AL-Gamal M.A. and Shams El-deen A.E. (2022). Effectiveness of caprylic acid and Yucca schidigera extract on productive and physiological performance of laying hens. Egyptian J. Nutr. Feeds. 25(1), 67-83.
Enaiat M.M.E., Eman M., Abou-Eitta A., Salem A. and Al-Kotait A.H.A. (2009). Effect of Yucca schidigera extract and alumi-num chloride on pen’s atmospheric ammonia, productive, re-productive and physiology performance of silver montazah cocks. Egyptian J. Poult. Sci. 29, 337-356.
Enginar H., Avci G., Eryavuz A., Kaya E., Kucukkurt I. and Fidan A.F. (2006). Effect of Yucca schidigera extract on lipid per-oxidation and antioxidant activity in rabbits exposed to γ ra-diation. Rev. Méd. Vét. 157(8), 415-419.
Farag M.R., Alagawany M., EI-Hack M.E.A., EI-Sayed S.A.A., Ahmed S.Y.A. and Samak D.H. (2018). Yucca schidigera ex-tract modulates the lead-induced oxidative damage, nephropa-thy and altered inflammatory response and glucose homeosta-sis in Japanese quails. Ecotoxicol. Environ. Saf. 156, 311-321.
Franchis G., Kerem Z., Makkar H.P.S. and Becker K. (2002). The biological action of saponins in animal systems: A review. Br. J. Nutr. 88(6), 587-605.
Gaber M.M. (2006). The effects of plant-protein based diets sup-plemented with Yucca on growth, digestibility, and chemical composition of Nile Tilapia (Oreochromis niloticus) inger-lings. J. World Aquac. Soci. 37(1), 74-81.
Galli G.M., Da Silva A.S., Bottari N.B., Biazus A.H., Petrolli T., Reis J.H., Morsch V.M., Schetinger M.R.C., Piva M.M., Bag-gio R.A., Mendes R.E., Boiago M.M., Stefani L.M. and Machado G. (2018). Addition of yucca extract and glutamine in the diet of chicks had a protective effect against coccidiosis. Comp. Clin. Pathol. 27(1), 205-214.
Galli G.M., Griss L.G., Boiago M.M., Petrolli T.G., Glombowsky P., Bissacotti B.F., Copetti P.M., da Silva A.D., Schetinger M.R., Sareta L., Mendes R.E., Mesadri J., Wagner R., Gundel S., Ourique A.F. and Da Silva A.S. (2020). Effects of curcu-min and Yucca extract addition in feed of broilers on microor-ganism control (anticoccidial and antibacterial), health, per-formance and meat quality. Res. Vet. Sci. 132, 156-166.
Gao D., Zhao M., Qi X., Liu Y., Li N., Liu Z. and Bian Y. (2016). Hypoglycemic effect of Gynostemma pentaphyllum saponins by enhancing the Nrf2 signaling pathway in STZ-inducing diabetic rats. Arch. Pharm. Res. 39(2), 221-230.
Guclu B. (2003). The effects of Yucca schidigera extract added to quail rations on egg production, egg quality and some blood parameters. Turkish J. Vet. Anim. Sci. 27(3), 567-574.
Guclu B. and Iscan K.M. (2004). The effects of Yucca schidigera extract added to quail rations on fattening performance. J. Er-ciyes. Univ. Fac. Vet. Med. 1, 5-20.
Gupta S. (2014). Inhibitory potential of Yucca gloriosa L. extract and isolated gloriosaol isomeric mixture on ovalbumin in-duced airway hyperresponsiveness in Balb/C mice. Clin. Pharmacol. Biopharm. 2(1), 1-9.
Gurbuz E., Balevi T., Kurtoglu V. and Oznurlu Y. (2011). Effects of adding yeast cell walls and Yucca schidigera extract to diets of layer chicks. Br. Poult. Sci. 52(5), 625-631.
Gurbuz E., Balevi T., Kurtoglu V. and Oznurlu Y. (2016). Use of yeast cell walls and Yucca shidigera extract in layer hens’ di-ets. Italian J. Anim. Sci. 10(2), 26-34.
Hassan S.M., Byrd J.A., Cartwright A.L. and Bailey C.A. (2010). Haemolytic and antimicrobial activities differ among saponin-rich extracts from guar, quillaja, yucca, and soybean. Appl. Biochem. Biotechnol. 162(4), 1008-1017.
Johnston N.L., Quarles C.L., Fagerberg D.J. and Caveny D.D. (1981). Evaluation of yucca saponin on broiler performance and ammonia suppression. Poult. Sci. 60(10), 2289-2292.
Jun-Ling S., Bin-Lin S., Peng-Fei Z., Deng-Sheng S., Ti-Yu L. and Su-Mei Y. (2016). Effects of Yucca extract on feed effi-ciency, immune and antioxidative functions in broilers. Braz. Arch. Biol. Technol. 59, 1-11.
Kaya S., Erdogan Z. and Erdogan S. (2003). Effect of different dietary levels of Yucca schidigera powder on the performance, blood parameters and egg yolk cholesterol of laying quails. J. Vet. Med. A Physiol. Pathol. Clin. Med. 50(1), 14-17.
Kelly A.M. and Kohler C.C. (2003). Effects of Yucca schidigera extract on growth, nitrogen retention, ammonia excretion, and toxicity in channel catfish Ictalurus punctatus and hybrid tila-pia O. mossambicus × O. niloticus. J. World Aquac. Soci. 34(2), 156-161.
Khaskheli A.A., Khaskheli M.I. and Khaskheli A.J. (2020). Die-tary influence of Yucca schidigera on broilers and layers: A Review. Int. J. Vet. Sci. 9, 458-461.
Kim D.H., Moon Y.S., Jung J.S., Min S.K., Son B.K. and Suh H.W. (2003). Effects of ginseng saponin administered intrap-eritoneally on the hypothalamo-pituitary-adrenal axis in mice. Neurosci. Lett. 343(1), 62-65.
Kozłowski K., Vervenne-Zetteler P., Konieczka P., Szyma´ nski Ł. and van Vilsteren A. (2022). Yucca schidigera improves performance and lowers oocyst counts in Eimeria challenged broilers. Animals (Basel). 12(13), 1668-1678.
Kucukkurt I., Akkol E.K., Karabag F., Ince S., Süntar I., Eryavuz A. and Sözbilir N.B. (2016). Determination of the regulatory properties of Yucca schidigera extracts on the biochemical pa-rameters and plasma hormone levels associated with obesity. Rev. Bras. Farmacogn. 26(2), 246-250.
Kutlu H.R., Görgülü M. and Ünsal I. (2001). Effects of dietary Yucca schidigera powder on performance and egg cholesterol content of laying hens. J. Appl. Anim. Res. 20(1), 49-56.
Lan J., Wang K., Chen G., Cao G. and Yang C. (2020). Effects of inulin and isomalto oligosaccharide on diphenoxylate-induced constipation, gastrointestinal motility-related hormones, short-chain fatty acids, and the intestinal flora in rats. Food Function J. 11(10), 9216-9225.
Li W.B., Wang H.Y., Ma Y.M., Zhao X.H., Yang H., Qian J.M. and Li J.N. (2018). VSL#3 can prevent ulcerative colitis-associated carcinogenesis in mice. World J. Gastroenterol. 24(37), 4254-4262.
Liang G., Wang X., Wang X., Li C. and Chen G. (2009). Effects of camphor familial plant extract and Yucca extracts on emis-sion of NH3 and H2S in slurry of weaned pigs. Chin. J. Anim. Sci. 45, 22-26.
Lillehoj H., Liu Y., Calsamiglia S., Fernandez-Miyakawa M.E., Chi F., Cravens R.L., Oh S. and Gay C.G. (2018). Phyto-chemicals as antibiotic alternatives to promote growth and en-hance host health. Vet. Res. 49(1), 76-75.
Luo X., Zheng C., Xia W., Ruan D., Wang S., Zhang Y.N. and Chen W. (2018). Effects of constant or intermittent high tem-perature on the feed intake, hypothalamic expression of anti-oxidant and pro-oxidant enzymes genes in laying ducks. J. Anim. Sci. 96(12), 5064-5074.
Luo J.J., Chen W., Qu H., Liu Y.Q., Luo C.L., Ji J., Shu D.M. and Wang J. (2022). Dietary supplementation with Yucca allevi-ates heat stress in growing broilers exposed to high ambient temperature. Front. Vet. Sci. 9, 850715-850723.
Lundeen T. (2000). Yucca extract improves feed efficiency, de-creases abdominal fat in broilers. Feedstuffs Repr. 72, 1-9.
Malecki J.A., Ramisz L., Mardarowicz L. and Pilarczyk B. (1995). The influence of Yucca shidigera extract on environment and productivity of broilers. Zeszyty Naurokowe Akademii Rolnic-zej w. Szczecinie, Zootechnica. 32, 51-56.
Mao X., Dou Y., Fan X., Yu B., He J., Zheng P., Yu J., Luo J., Luo Y., Yan H., Wang J., Wang H. and Wang Q. (2023). The effect of dietary Yucca schidigera extract supplementation on productive performance, egg quality, and gut health in laying hens with Clostridium perfringens and coccidia challenge. Poult. Sci. 102(8), 102822-102832.
Martin-Gallausiaux C., Marinelli L., Blottière H.M., Larraufie P. and Lapaque N. (2021). SCFA: Mechanisms and functional importance in the gut. Proc. Nutr. Soc. 80(1), 37-49.
Matusiak K., Oleksy M., Borowski S., Nowak A., Korczyński M., Dobrza´nski Z. and Gutarowska B. (2016). The use of Yucca schidigera and microbial preparation for poultry manure de-odorization and hygienization. J. Environ. Manag. 170, 50-59.
McAllister T.A., Annett C.B., Cockwill C.L., Olson M.E., Wang Y. and Hahn T.W. (2001). Studies on the use of Yucca schidigera to control giardiosis. Vet. Parasitol. 97(2), 85-99.
Mert S. (2025). Effects of humate, Yucca, and humate-Yucca combination supplementation on growth performance, gut health, and immune response in broiler chickens. Front. Vet. Sci. 12, 1-11.
Munezero O., Zhang Z. and Kim I. (2023). The effects of Yucca Schidigera extract and multi-carbohydrase in different crude protein diets on growth performance, nutrient digestibility, carcass parameters and excreta noxious gas contents in broil-ers. Brazilian J. Poult. Sci. 25(1), 1-8.
Nazeer M.S., Pasha T.N., Shahid A. and Ali Z. (2002). Effect of Yucca saponin on urease activity and development of ascites in broiler chickens. Int. J. Poult. Sci. 1(6), 174-178.
Obianwuna U.E., Chang X., Oleforuh O.V.U., Onu P.N., Zhang H., Qiu K. and Wu S. (2024). Phytobiotics in poultry: Revolu-tionizing broiler chicken nutrition with plant-derived gut health enhancers. J. Anim. Sci. Biotechnol. 15, 169-175.
Oelschlager M.L., Rasheed M.S.A., Smith B.N., Rincker M.J. and Dilger R.N. (2019). Effects of Yucca schidigera derived saponin supplementation during a mixed Eimeria challenge in broilers. Poult. Sci. 98(8), 3212-3222.
Oleszek W., Sitek M., Stochmal A., Piacente S., Pizza C. and Cheeke P. (2001). Resveratrol and other phenolics from the bark of Yucca schidigera roezl. J. Agric. Food Chem. 49(2), 747-452.
Oviedo E.O., Parker J., Clack B. and Waetherford W. (2003). Concentrate Extract of Yucca schidigera (BioSupreme®) Plant as Feed Additive in Broiler Diets in the Control of Eimeria In-fection. Austin State University, Nacogdoches, TX, USA.
Patel S. (2012). Yucca: A medicinally significant genus with manifold therapeutic attributes. Nat. Prod. Bioprospect. 2(6), 231-234.
Patoary M.U., Hossain M., Akter M. and Rubel Z.U. (2020). Ef-fect of supplementation of Yucca schidigera extract on ammo-nia gas emission and performance of broiler chickens. J. World Poult. Res. 10(1), 57-62.
Pen B., Sar C., Mwenya B., Kuwaki K., Morikawa R. and Taka-hashi J. (2006). Effects of Yucca schidigera and Quillaja saponaria extracts on in vitro ruminal fermentation and meth-ane emission. Anim. Feed Sci. Technol. 129(3), 175-186.
Piacente S., Pizza C. and Oleszek W. (2005). Saponins and pheno-lics of Yucca schidigera Roezl: Chemistry and bioactivity. Phytochem. Rev. 4, 177-190.
Piacente S., Montoro P., Oleszek W. and Pizza C. (2004). Yucca schidigera bark: phenolic constituents and antioxidant activity. J. Nat. Prod. 67(5), 882-885.
Preston C.M., McCracken K.J. and Bedford M.R. (1999). Effects of Yucca schdigera extract, Saccharomyces boulardii and en-zyme supplementation of wheat-based diets on broiler per-formance and diet metabolisability. Br. Poult. Sci. 40(1), 39-40.
Rahman M.M., Begum S. and Mondol S.I.A.K. (2023). Impact of Yucca schidigera plant extract supplementation to diet on body growth, carcass characteristic’s, gut microbiota, intesti-nal ammonia concentration and hematology in broiler chick-ens. J. Sylhet Agric. Univ. 10(1), 17-22.
Ranjbar Z., Shariatmadari F. and Torshizi M.K. (2014). Effect of different levels of yucca extract and antibiotic on growth per-formance, immune response and blood factors of broiler chickens. Iranian J. Med. Aromat. Plants. 30(5), 675-681.
Rezaei R., Lei J. and Wu G. (2017). Dietary supplementation with Yucca schidigera extract alleviates heat stress–induced growth restriction in chickens. J. Anim. Sci. 95(4), 370-371.
Saddoris-Clemons K., Osho S., Garcia M. and Humphrey B. (2024). Effects of dietary inclusion of a proprietary combina-tion of Quillaja saponaria and Yucca schidigera on intestinal permeability and immune response in broiler chickens during a coccidia challenge. Animals. 14(12), 1737-1745.
Saeed M., Arain M.A., Naveed M., Alagawany M., Abd El-Hack M.E., Bhutto Z.A. and Chao S. (2018). Yucca schidigera can mitigate ammonia emissions from manure and promote poul-try health and production. Environ. Sci. Pollut. Res. Int. 25(35), 35027-35033.
Saleh A.A., Paray B.A. and Dawood M.A.O. (2020). Olive cake meal and Bacillus licheniformis impacted the growth perform-ance, muscle fatty acid content, and health status of broiler chickens. Animals. 10(4), 695-701.
Sahoo S.P., Kaur D., Sethi A.P., Sharma A. and Chandra M. (2015). Evaluation of Yucca schidigera extract as feed addi-tive on performance of broiler chicks in winter season. Vet. World. 8(4), 556-560.
Sahoo S., Kaur D., Sethi A., Saini A. and Chandra M. (2016). Effect of dietary supplementation of yucca schidigera extract on the performance and litter quality of broilers in winter sea-son. Anim. Nutr. Feed Technol. 16(3), 475-484.
Sariozkan S., Konca Y., Guclu B.K., Kara K., Ildiz N., Kirkpinar F., Beyzi S.B. and Kaliber M. (2015). Effects of dietary sup-plementation of dried distillers grain with solubles (DDGS) and yucca (Yucca schidigera) on broiler performance, carcass traits, intestinal viscosity and marketing. J. Poult. Res. 12(1), 5-11.
Sidhu G. and Oakenfull D.A. (1986). Mechanism for the hypocho-lesterolaemic activity of saponins. Br. J. Nutr. 55(3), 643-649.
Song X. and Hu S. (2009). Adjuvant activities of saponins from traditional Chinese medicinal herbs. Vaccine. 27(36), 4883-4890.
Su J.L., Shi B.L., Zhang P.F., Sun D.S., Li T.Y. and Yan S.M. (2016). Effects of Yucca extract on feed efficiency, immune and antioxidative functions in broilers. Braz. Arch. Biol. Tech-nol. 59, 1-9.
Sun D.S., Shi B.L., Tong M.M. and Yan S.M. (2017). Improved performance and immunological responses as a result of die-tary Yucca schidigera extract supplementation in broilers. Ital-ian J. Anim. Sci. 17(2), 511-517.
Sun D., Jin X., Camerlink I., Tong M., Su J., Zhao F., Yan S. and Shi B. (2019). Effects of Yucca schidigera extract on growth performance and antioxidative function of small intestine in broilers. J. Anim. Physiol. Anim. Nutr. 103(3), 738-346.
Sun X., Wang Z., Li X., Du S., Lin D. and Shao Y. (2023). Effects of Yucca schidigera extract on serum biochemical parameters, humoral immune response, and intestinal health in young pi-geons. Front. Vet. Sci. 9, 77555-77564.
Trejo Castro L. (2002). Report of the Evaluation of Effectiveness of the Product Yucca schidigera as Anticoccidial in Broiler Feed; LAB.PAR.IND2001 003; Baja Agro International, En-senada, Mexico.
Tsukahara T. and Ushida K. (2000). Effects of animal or plant protein diets on cecal fermentation in Guinea pigs (Cavia por-cellus), rats (Rattus norvegicus) and chicks (Gallus gallus do-mesticus). Comp. Biochem. Physiol. A Mol. Integr. Physiol. 127(2), 139-146.
Tugay A., Yurtseven S., Baylan M. and Canogullari S. (2005). The effects of dietary Yucca shidigera on egg yield parameters and egg shell quality of laying hens. Int. J. Poult. Sci. 4, 159-162.
Vlčková R., Sopková D., Andrejčáková Z., Valocký I., Kádasi A., Harrath A.H., Petrilla V. and Sirotkin A.V. (2017). Dietary supplementation of yucca (Yucca schidigera) affects ovine ovarian functions. Theriogenology. 88, 158-165.
Wang Y., Mcallister T.A., Newbold C.J., Rode L.M., Cheeke P.R. and Cheng K.J. (1998). Effects of Yucca schidigera extract on fermentation and degradation of steroidal saponins in the ru-men simulation technique (RUSITEC). Anim. Feed Sci. Tech-nol. 74(2), 143-153.
Wang J.P. and Kim I.H. (2011). Effect of caprylic acid and Yucca schidigera extract on production performance, egg quality, blood characteristics, and excreta microflora in laying hens. Br. Poult. Sci. 52(6), 711-717.
Wang L., Wu D., Fan Z., Li H., Li J., Zhang Y., Xu Q., Wang G. and Zhu Z. (2020). Effect of Yucca schidigera extract on the growth performance, intestinal antioxidant status, immune re-sponse, and tight junctions of mirror carp (Cyprinus carpio). Fish Shellfish Immunol. 103, 211-219.
Wang Y., Zhang Y., Ren H., Fan Z., Yang X., Zhang C. and Jiang Y. (2023). Dietary Yucca extract and Clostridium butyricum promote growth performance of weaned rabbits by improving nutrient digestibility, intestinal development, and microbial composition. Front. Vet. Sci. 10, 1-8.
Yang Y., Lee J., Rhee M.H., Yu T., Baek K.S., Sung N.Y., Kim Y., Yoon K., Kim J.H., Kwak Y.S., Hong S., Kim J.H. and Cho J.Y. (2015). Molecular mechanism of protopanaxadiol saponin fraction-mediated anti-inflammatory actions. J. Gin-seng. Res. 39(1), 61-68.
Yeo J. and Kim K.I. (1997). Effect of feeding diets containing an antibiotic, a probiotic, or yucca extract on growth and intesti-nal urease activity in broiler chicks. Poult. Sci. 76(2), 381-385.
Zdanowska-Sąsiadek Z., Lipińska-Palka P., Damaziak K., Michalczuk M., Grzybek W., Kruzi´nska B., Jasi´nska K., Róg D., Kordos K. and Abek K. (2019). Antioxidant effects of phytogenic herbal-vegetable mixtures additives used in chicken feed on breast meat quality. Anim. Sci. Pap. Rep. 37(4), 393-408.
