Exploratory Analysis of Systemic Illness and Associated Medication on Salivary Flow Rate, pH and Clinical Oral Dryness: A Cross-sectional Study

الموضوعات : Journal of Chemical Health Risks

Namrata Prakash ¹ , Junaid Ahmed ² , Nanditha Sujir ³ , Nandita Shenoy ⁴ , Archana Muralidharan ⁵ , Srikant Natarajan ⁶

1 - Department of Oral Medicine and Radiology, Manipal College of Dental Sciences Mangalore, Manipal Academy of Higher Education, Manipal, India
2 - Department of Oral Medicine and Radiology, Manipal College of Dental Sciences Mangalore, Manipal Academy of Higher Education, Manipal, India
3 - Department of Oral Medicine and Radiology, Manipal College of Dental Sciences Mangalore, Manipal Academy of Higher Education, Manipal, India
4 - Department of Oral Medicine and Radiology, Manipal College of Dental Sciences Mangalore, Manipal Academy of Higher Education, Manipal, India
5 - Department of Oral Medicine and Radiology, Manipal College of Dental Sciences Mangalore, Manipal Academy of Higher Education, Manipal, India
6 - Department of Oral pathology & Microbiology, Manipal College of Dental Sciences Mangalore, Manipal Academy of Higher Education, Manipal, India

تاريخ الإرسال : 21 الجمعة , رمضان, 1446 تاريخ التأكيد : 04 الثلاثاء , جمادى الثانية, 1447 تاريخ الإصدار : 06 الأحد , ربيع الثاني, 1447

الکلمات المفتاحية: Chronic Diseases, Diabetes Mellitus, Drug Side Effects, Hypertension, Saliva, Psychiatric Diseases, Xerostomia,

ملخص المقالة :

The aim of the study was to analyse the effects of systemic illnesses, and medications on the salivary flow, salivary pH, and clinical oral dryness score. A cross-sectional comparative study was done on 51 patients. Consecutive patients visiting the outpatient department fulfilling the inclusion criteria were included in the study after obtaining informed consent. Current illnesses, its duration and type of medications taken for the same were duly recorded.  The salivary flow rate was assessed by Schirmer tear strips, pH by pH strips, and xerostomia by Clinical oral dryness score. Descriptive statistics, independent t test, one-way ANOVA and Posthoc Tukey test was utilized for statistical analysis. p value <0.5 was considered significant. 51 patients of which 28 were males and 23 were females were broadly divided into 3 groups namely the Systemic illness group (Group 1), the Psychiatric illness group (Group 2) and a healthy control group (Group 3). After a detailed assessment of the salivary flow rate, salivary pH, and clinical oral dryness score across the three groups, we found a significant difference in the salivary flow rate in comparison to control group. A thorough assessment of salivary flow, salivary pH, and other measurable parameters among the vulnerable groups like those with systemic disorders or with a positive history of psychiatric illness is needed at regular intervals for improving an individuals’ general health and well-being and ensure a better quality of life.

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