آرایههای میکروسوزن: مروری بر اصول، کاربردها و پیشرفتهای اخیر
الموضوعات : کاربرد شیمی در محیط زیستnoushin dadashzadeh 1 , الناز پوررضا 2 , ناصر مصلحی میلانی 3
1 - Department of physics, Faculty of physics,Hadishahr Branch, Islamic Azad University, Hadishahr, Iran.
2 - گروه آموزشی برق، دانشگاه آزاد اسلامی واحد ارس، شهر جلفا، ایران
3 - گروه فیزیک، واحد اهر، دانشگاه آزاد اسلامی، اهر، ایران
الکلمات المفتاحية: آرایه میکروسوزن, انتقال پوستی دارو, میکروسوزن جامد, میکروسوزن خالی, میکروسوزن متخلخل, میکروسوزن قابل حل, میکروسوزن متورم,
ملخص المقالة :
آرایههای میکروسوزن (MNA) ابزارهای نوآورانهای هستند که از سوزنهای ریز در ابعاد چند ده میکرون تا چند میلیمتر تشکیل شدهاند. این ریزساختارها که از مواد مختلفی مانند فلزات، پلیمرها، سرامیکها و مواد زیستسازگار ساخته میشوند، کاربردهای گستردهای را در زمینههای مختلف پزشکی به ارمغان آوردهاند. MNAها با نفوذ به لایههای بالایی پوست یا بافتهای دیگر، روشهای نوینی را برای انتقال دارو، واکسیناسیون، نمونه برداری و تشخیص بیماریها ارائه میدهند.
در این مطالعه تلاش خواهیم کرد تا با بهرهگیری از تحقیقات روز دنیا و جزئیات بیشتر، اطلاعات دقیقتری را درباره میکرونیدلها و کاربردهای آنها در حوزههای زیباییشناسی، پزشکی و سایر زمینهها بدست آوریم. به علاوه، نقاط ضعف و چالشهایی که در استفاده از این فناوری وجود دارد نیز بررسی و تحلیل میشوند تا در آینده بتوانیم از میکروسوزنها بهره بیشتری ببریم و نقاط قوت آنها را بهبود دهیم. همچنین، بررسی دقیقتر و دستهبندی بهتر انواع میکروسوزنها و تاثیرات آنها بر روی پوست و بافتهای تحت تأثیر آنها نیز به دلیل اهمیتشان در استفاده از این فناوری صورت خواهد گرفت. در نهایت با ترکیب دادهها و نتایج بدست آمده راهکارهای بهبود و ارتقای استفاده از میکروسوزنها و توسعهی کاربردهای جدید در این حوزه را خواهیم داشت.
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