Difference In Effectiveness Between The Topical Application of Acidulated Phosphate Fluoride (APF) Gel and Casein Phosphopeptide-Amorphous Calcium Phosphate (CPP-ACP) Paste in Reducing Plaque Accumulation in Children
الموضوعات :
Septriyani Kaswindiarti
1
(Faculty of Dentistry, Universitas Muhammadiyah Surakarta, Jawa Tengah, Indonesia)
Fianita Finhartanti
2
(Faculty of Dentistry, Universitas Muhammadiyah Surakarta, Jawa Tengah, Indonesia)
Syed Muhammad Mamduh
3
(Centre of Excellence for Advanced Sensor Technology (CEASTech), Universiti Malaysia Perlis, Malaysia)
Mohammad Iqbal Omar
4
(School of Mechatronic Engineering, Universiti Malaysia Perlis, Malaysia)
الکلمات المفتاحية: Streptococcus mutans, Plaque accumulation, APF, CPP-ACP, Plaque score, Topical aplication,
ملخص المقالة :
Plaque accumulation is the buildup of bacterial substances on dental surface. Plaque can be controlled using anti-bacterial chemicals such as acidulated phosphate fluoride (APF) and casein phosphopeptide-amorphous calcium phosphate (CPP-ACP). The function of APF and CPP-ACP is to inhibit the growth and adhesion of bacterial plaque colonization by S. mutans on the tooth’s surface. This study aims to identify differences in the effectiveness of the topical application of APF gel and CPP-ACP paste against plaque accumulation in children. The research applied a quasi-experimentalmethod with a time-series design. The study was conducted at the Nur Hidayah and Ihsan Sakeena orphanages in Surakarta, where 30 children aged 6-12 were involved as research subjects, divided into two treatment groups namely the APF and CPP-ACP groups. Topical application of APF was given once on the first day, while that of CPP-ACP was administered once a day from the first until the seventh day. Plaque score data were obtained by PHP-M plaque score measurement. Total plaque scores were measured on day 1 before and after application, day 7 and day 14. Results show declining average plaque scores between the first day prior to topical application of APF and CPP-ACP and the fourteenth day afterwards. Independent samples tests reveal differences in effectiveness of topical APF gel and CPP-ACP paste application on plaque accumulation in children on day 7 and day 14, but no difference in plaque score change on day 1 ahead of and following application. Topical application of CPP-ACP paste decreases plaque accumulation in children more effectively than that of APF gel.
1. Guswan G., Yandi S., 2017. Hubungan Pengetahuan Dan Tindakan Ibu Terhadap Indeks Plak Anak Tk Ibnu Akbar Jalan Parak Pegambiran Kecamatan Lubuk Begalung Padang. Jurnal Kedokteran Gigi. 29(4), 7-9.
2. Savitri G., Primarti R., Gartika M., 2017, Hubungan frekuensi asupan minuman manis dengan akumulasi plak pada anak. J Ked Gi. 29(2), 2-5.
3. Asif, M., Mohd, I., 2019, Prospects of Medicinal Plants Derived Nutraceuticals: A Re-emerging New Era of Medicine and Health Aid, Progress in Chemical and Biochemical Research, 2(4), 150-169.
4. El-Shahaby, O., El-Zayat, M., Rabei, R., Aldesuquy, H. S., 2019, Phytochemical constituents, antioxidant activity and antimicrobial potential of Pulicaria incisa (lam.) DC as a folk medicinal plant, Progress in Chemical and Biochemical Research, 2(4), 222-227.
5. Khan Muluh, E., Odokpe Ugbede, A., Tor-Anyin, T. A., 2019, Screening of Cassia Sieberiana (Fabaceae) Leaf Extract for In-Vitro Anti Microbial and Anti-Ulcer Activities, Progress in Chemical and Biochemical Research, 2(3), 143-149.
6. Heasman P., 2013. Restorative Dentistry, Paediatric Dentistry and Orthodontics, 3rd ed., Churchill Livingstone. Newcastle upon Tyne. hal. pp.130-220.
7. Rezki S., dan Pawarti., 2014. Pengaruh PH Plak Terhadap Angka Kebersihan Gigi Dan Angka Karies Gigi Anak Di Klinik Pelayanan Asuhan Poltekkes Pontianak Tahun 2013, ODONTO Dental Journal. 1(2), 13-17.
8. El-Khateeb, A., 2020, Practical Biochemistry Principles and Techniques Approach, Progress in Chemical and Biochemical Research, 3(3),180-193.
9. Elliott, C., Vaillant, A., 2020, Antimicrobials and Enterobacterial Repetitive Intergenic Consensus (ERIC) Polymerase Chain Reaction (PCR) Patterns of Nosocomial Serratia Marcescens Isolates: A One Year Prospective Study (June 2013-May 2014) in a Rural Hospital in the Republic of Trinidad and Tobago Progress in Chemical and Biochemical Research, 3(2), 105-120.
10. Kidd E.A.M., Bechal S.J., 2013. Dasar-Dasar Karies Penyakit dan Penanggulangan, EGC., Jakarta, hal. 98-118.
11. Tavakkoli H., Salandari S., 2014. Pathological Evaluation of Essential Amino Acid Injection for Chicken Embryonated Eggs. International Journal of Advanced Biological and Biomedical Research. 2 (12), 2874-2879.
12. Iranparast F., Parsaei S., Houshmand M., Naghiha A., 2014. The Effect of Oral Consumption of Guggul (Commiphora Mukul) Resin on Performance and Humoral Immunity Response of Broilers. International Journal of Advanced Biological and Biomedical Research. 2(3), 802-810.
13. Sirat N., 2014. Pengaruh Aplikasi Topikal Dengan Larutan NaF dan SnF2 Dalam Pencegahan Karies Gigi, Jurnal Kesehatan Gigi. 2(2), 222-231.
14. Al-Batayneh O., 2009, The Clinical Applications of Tooth Mousse TM and CPP-ACP Products in Caries Prevention: evidence-based recommendations, Smile Dental Journal. 4 (1), 8-12.
15. Andrini M., Titien I., Rantinah S., 2013, Pengaruh Aplikasi Topikal Casein Phosphopeptide Amorphous Calcium Phosphate (CPP-ACP) Terhadap Pertumbuhan Stereptococcus Alpha dan Akumulasi Plak Gigi. J Ked Gi. 4(4), 268-272.
16. Sriyono, Widiyanti N., 2009. Ilmu Kedokteran Pencegahan, Medika FK UGM., Yogyakarta. pp. 31-40.
17. Karaarslan E.S., Aytac F., Cadirci B.H., Agaccioglu M., Tastan E., Yilmaz G., Ozkocak B.B.C., 2018. Evaluation of the Effects of Different Remineralizing agents on Streptococcus mutans Biofilm Adhesion. Journal of Adhesion Science and Technology. 32(23), 2617-2627.
18. Tedjosasongko U., Pradopo S., dan Nuraini P., 2008. Perubahan Oral Flora Dan Sensitifitas Karies Gigi Anak Setelah Pengulasan Fluoride Secara Topikal. J Penelit Med Eksakta. 7(1), 9-15.
19. Chandak S., Bhondey A., Bhardwaj A., Pimpale J., Chandwani M., 2016. Comparative Evaluation of the Efficacy of Fluoride Varnish-Casein Phosphopeptide Amorphous Calcium Phosphate in Reducing Streptococcus Mutans Counts in Dental Plaque of Children: An in vivo study. Journal of International Society of Preventive and Community Dentistry. 6(5), 423-426.
20. Nongonierma A.B., FitzGerald R.J., 2012, Biofunctional Properties of Caseinphosphopeptides in the Oral Cavity, Caries Reseacrh. 46, 234-267.
21. Samimi A., Zarinabadi S., Shahbazi Kootenaei A., Azimi A., Mirzaei M., 2020, Considering different kinds of gasoline unit catalysts, Journal of Medicinal and Chemical Sciences. 3, 79-94.
