Evaluation of In-vitro Antimicrobial Activity of some Newly Synthe-sized2-amino-3-phenylsulfonyl-4-aryl-4H-benzo[h]chromens Derivatives
الموضوعات :
Farzaneh Manouchehri
1
(Department of Chemistry, Yazd Branch, Islamic Azad University, Yazd, Iran)
Bahareh Sadeghi
2
(Department of Chemistry, Yazd Branch, Islamic Azad University, Yazd, Iran)
Farhood Najafi
3
(Department of Resin and Additives, Institute for Color Science and Technology, P.O. BOX: 16765-654, Tehran, Iran)
Mohammad Hossein Mosslemin
4
(Department of Chemistry, Yazd Branch, Islamic Azad University, Yazd, Iran)
الکلمات المفتاحية: antibacterial activity, 4H-Chromens deriva-tives, Microdilutionbroth, Disk Diffusion Agar test,
ملخص المقالة :
In this study, some chromens derivatives were synthesized as mentioned in our previous report.The synthesized compounds were evaluated for their antibacterial effect against three different bacterial species, using Disk Diffusion Agar test and microdilution broth (MIC) method against the S. aureus, E. coli, P. aeruginosabacterias according to the National Committee for Clinical Laboratory Standards (NCCLS) recommendations. The results indicated that 4-nitro compound has considerable antibacterial activity against S. aureusbacteria. Moreover, compound 3-chloro has antibacterial properties againstE. coli standard strain and none of 4H-Chromens derivatives have antibacterial effect on P. aeruginosa strains.
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