The Effects of Environmental Pollution with Heavy Metals in Frequency of Micronuclei in Epithelial Buccal Cells of Human Population in Mitrovica

الموضوعات :

K. Letaj ¹ ()
I. Elezaj ² ()
Q. Selimi ³ ()
K. Kurteshi ⁴ ()

تاريخ الإرسال : 26 الثلاثاء , صفر, 1434 تاريخ التأكيد : 20 الإثنين , صفر, 1440 تاريخ الإصدار : 14 السبت , شوال, 1433

الکلمات المفتاحية: Heavy metals, DNA, micronuclei, buccal cells,

ملخص المقالة :

The purpose of this study was evaluation of genotoxic effects of environmental pollution with heavy metals in inhabitants of Mitrovica town (which is located close to smelter “Treça” down closed). In this study, 55 inhabitants (males) from Mitrovica town and 20 (males) control subjects with similar mean ages and smoking prevalence were enrolled for analysis of micronuclei frequency in epithelial buccal cells. The subjects of Mitrovica town showed significant increase micronuclei frequency (p< 0.001) in epithelial buccal cells compared to controls and with respect to their smoking habits. The current study suggests that chronic exposure to pollution with heavy metals could lead to increase of DNA damage.

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