Influence of Using Sage Powder (Salvia officinalis) on Performance, Blood Cells, Immunity Titers, Biochemical Parameters and Small Intestine Morphology in Broiler Chickens
الموضوعات :م. فرهادی 1 , م. هدایتی 2 , م. منافی 3 , س. خلجی 4
1 - Department of Animal Science, Faculty of Agricultural Science, Malayer University, Malayer, Iran
2 - Department of Animal Science, Faculty of Agricultural Science, Malayer University, Malayer, Iran
3 - Department of Animal Science, Faculty of Agricultural Science, Malayer University, Malayer, Iran
4 - Department of Animal Science, Faculty of Agricultural Science, Malayer University, Malayer, Iran
الکلمات المفتاحية: performance, immunity, blood characteristic, ileal morphology, sage powder,
ملخص المقالة :
An experiment was performed to investigate the effect of using sage powder (Salvia officinalis) on performance, blood cells, immunity titers, biochemical parameters and small intestine morphology in broiler chickens. A total of 200 Ross 308 broiler chickens were assigned in a completely randomized design with four treatments and five replicates and ten chicks in each replicate. Experiment has been done from 1 to 42 days old. The experimental groups consisted of a control group receiving basal diet and basal diet supplemented with 0.2, 0.5 and, 1.2% of sage powder. The results of the experiment revealed that supplementation of 0.5% of salvia powder significantly (P≤0.05) increased body weight (BW) and reduced feed conversion ratio (FCR). An increase in eosinophil, monocyte and, heterophil as well as immunity titers against Newcastle disease and avian influenza viruses were observed where in the control diet was supplement with 0.2% of Salvia powder. The plasma cholesterol, triglyceride, and low-density lipoprotein (LDL) concentration were reduced and high-density lipoprotein (HDL) concentration was increased significantly by inclusion of 0.2% sage powder. Additionally, ileal villus height and intestinal health index was increased and the number of gablet cells and crypt depth was reduced significantly (P≤0.05) by incorporation of 0.2% sage powder in basal diet. In conclusion, supplementation of 0.2-0.5% sage powder had meaningful impact on broiler performance, ileal morphology and vaccine titer against Newcastle disease and avian influenza.
Ahmadi R. and Abdullahi A. (2012). Effect of Salvia officinalis extract on alkaline phosphatase and creatine kinase enzymes in male rats. Razi J. Med. Sci. 19(96), 20-25.
Alcicek A., Buzkurt M., and Cabuk M. (2004). Effect of an essential oil combination derived from selected herbs growing wild in Turkey on broiler performance. South African J. Anim. Sci. 34, 217-222.
Amoozmehr A. and Dastar B. (2009). Effect of alcoholic extract of Garlic (Allium sativum) and Thyme (Thyme vulgaris) on the performance and maintenance of blood lipids in broiler chickens. J. Agric. Sci. Nat. Res. 16(1), 62-68.
Bagherzadeh Kasmani F., Omidikia S., Mirzaei H. and Mehri M. (2014). The effect of salvia leaf powder on the protein performance and microbial population of blind chickens intestines. J. Anim. Prod. 16(2), 103-111.
Baurhoo B., Phillip L. and Ruiz-Feria C.A. (2007). Effects of purified lignin and mannan oligosaccharides on intestinal integrity and microbial populations in the ceca and litter of broiler chickens. Poult. Sci. 86, 1070-1078.
Capek P. and Hríbalová V. (2004). Water-soluble polysaccharides from Salvia officinalis possessing immune modulatory activity. Phytochemistry. 65, 1983-1992.
ČapkovIcova A., Makova Z., Piesova E., Adriana C. and Zuzana M. (2014). Evaluation of the effects of Salvia officinalis essential oil on plasma biochemistry, gut mucus and quantity of acidic and neutral mucins in the chicken gut, Acta Vet. 64(1), 138-148.
Demir E., Kilinc K., Yildirim Y., Dincer F. and Eseceli H. (2008). Comparative effects of mint, sage, thyme and flavomycinin wheat-based broiler diets. Arch. Zootech. 11(3), 54-63.
Demir E., Sarica S., Ozcan M.A. and Suicmez M. (2003). The use of natural feed additives as alternatives for an antibiotic growth promoter in broiler diets. British. Poult. Sci. 44, 44-45.
Dhanapakiam P., Mini-Joseph J., Ramaswamy U.K., Moorthy M. and Senthilkumar A. (2008). The cholesterol lowering property of coriander seeds (Coriandrum sativum): Mechanism of action. J. Environ. Biol. 29, 53-56.
Eidi M., Eidi A. and Bahar M. (2006). Effects of Salvia officinalis (sage) leaves on memory retention and its interaction with the cholinergic system in rats. Nutrition. 22, 321-326.
Fanimakki O., Ebrahimzade A., Ansarinik H. and Ghazaghi M. (2013). Effect of milk thistle (Silybum marianum) and thyme (Thymus vulgaris) herbs on immunity and some blood metabolites in broiler chicks. J. Vet. Clin. Pathol. 7(26), 1836-1843.
Frankic T., Voljic M., Salobir J. and Reza V. (2009). Use of herbs and spices and therir extracts in animal nutrition. Acta Agric. Slovenica. 94, 95-102.
Garcia V., Catala-Gregori P., Hernandez F., Megias M.D. and Madrid J. (2007). Effect of formic acid and plant extracts on growth, nutrient digestibility, intestine mucosa morphology, and meat yield of broilers. J. Appl. Poult. Res. 16, 555-562.
Ghorbani A. and Esmaeilizadeh M. (2017). Pharmacological properties of salvia officinalis and its components. J. Tradit. Complement. Med. 7(4), 433-440.
Hajati H., Hassanabadi A. and Ahmadian F. (2014). Application of medicinal plants in poultry nutrition. J. Med. Plan. By-prod. 1, 1-12.
Hayouni E.A., Chraief I. and Abedrabba M. (2008). Tunisian Salvia officinalis and Schinusmolle essential oils: Their chemical compositions and their preservative effects against Salmonella inoculated in minced beef meat. Int. J. Food Microbiol. 125, 242-251.
Hedayati M. and Manafi M. (2018). Evaluation of anherbal compound, a commercial probiotic, and an antibiotic growth promoter on the performance, intestinal bacterial population, antibody titers, and morphology of the jejunum and ileum of broilers, Brazilian J. Poult. Sci. 20(2), 305-316.
Hernandez-Saavedra D., Perez-Ramirez I.F., Ramos-Gomez M., Mendoza-Diaz S., Loarca-Pina G. and Reynoso-Camacho R. (2016). Phytochemical characterization and effect of Calendula officinalis, Hypericum perforatum, and Salvia officinalis infusions on obesity associated cardiovascular risk. Med. Chem. Res. 25, 163-172.
Horváthová E., Srančíková A. and Regendová-Sedláčková E. (2016). Enriching the drinking water of rats with extracts of Salvia officinalis and Thymus vulgaris increases their resistance to oxidative stress. Mutagenesis. 31, 51-59.
Khakpour S.H. and Khosravi M. (2014). The effect of Salvia officinalis extract on inflammation in male rats. J. Azad Univ. Med. Sci. 24, 136-142.
Khattab H.A.H., Mohamed R.A. and Hashemi J.M. (2012). Evaluation of hypoglycemic activity of Salvia officinalis infusion on streptozotocin-induced diabetic rats. J. Anim. Sci. 8, 411-416.
Kianbakht S. and Dabaghian F.H. (2013). Improved glycemic control and lipid profile in hyper lipidemic type 2 diabetic patients consuming Salvia officinalis leaf extract: a randomized placebo controlled clinical trial. Complement Ther Med. 21, 441-446.
Lee K.W., Kappert H.J., Frehner M., Losa R. and Beynen A.C. (2003). Effects of dietary essential oil components on growth performance, digestive enzymes and lipid metabolism in female broiler chickens. J. Appl. Poult. Res. 12, 394-399.
Martins E.R., Castro D.M. and Castelani D.C. (2003). Plantas Medicinais. Universidade Federal de Viçosa, Viçosa, MG, Brazil.
Mirzavand M., Rahimi S.H. and Sahari M. (2015). Effect of peppermint, parsley, dill, coriander, garlic and basil on performance, blood factors, immune system, intestinal morphology and meat taste in broilers. Iranian J. Med. Arom. Plant Res. 31, 446-459.
Montagne L. (2003). A review of interactions between dietary fiber and the intestinal mucosa, and their consequences on digestive health in young non-ruminant animals. J. Anim. Feed Sci. Technol. 108, 95-117.
Nobakht A. and Mehman-Navaz Y. (2010). Effect of thyme, peppermint, and mint medicinal plants on performance, egg quality, and blood parameters and immunity of laying chickens. Iranian J. Anim. Sci. 41, 129-136.
NRC. (1994). Nutrient Requirements of Poultry, 9th Rev. Ed. National Academy Press, Washington, DC., USA.
Pelicano E.R.L., Souza P.A., Souza H.B.A., Figueiredo D.F. and Amaral C.M.C. (2007). Morphometry and ultra-structure of the intestinal mucosa of broilers fed different additives. Brazilian J. Poult. Sci. 9(3), 173-180.
Pish Jang J. (2011). Effect of different levels of coriander oil on performance and blood parameters of broiler Chickens. Ann. Biol. Res. 2(5), 578-583.
Platel K. and Srinivasan K. (2003). Digestive stimulant action of spices: A myth or reality. Indian J. Med. Res. 119, 167-179.
Reisinger N., Steiner T., Nitsch S., Schatzmayr G. and Applegate T.J. (2011). Effects of a blend of essential oils on broiler performance and intestinal morphology during coccidial vaccine exposure. J. Appl.Poult. Res. 20, 272-283.
Ryzner M., Takáčová J., Čobanová K., Plachá I., Venglovská K. and Faix S. (2013). Effect of dietary salvia officinal is essential oil and sodium selenite supplementation on antioxidative status and blood phagocytic activity in broiler chickens. Acta Vet. Brno. 82, 43-48.
Sadeghi G.H., Karimi A., Padidar Jahromi S.H., Azizi T. and Daneshmand A. (2012). Effects of cinnamon, thyme and Turmeric infusions on the performance and immune response in of 1- to 21-day-old male broilers. Brazilian J. Poult. Sci. 14(1), 15-20.
Saki A.A., Aliarabi H., Hosseini Siyar S.A., Salari J. and Hashemi M. (2014). Effect of a phytogenic feed additive on performance, ovarian morphology, serum lipid parameters and egg sensory quality in laying hen. Vet. Res. Forum. 5(4), 287-293.
SAS Institute. (2009). SAS®/STAT Software, Release 9.2. SAS Institute, Inc., Cary, NC. USA.
Starcevi K., Krstulovic L., Brozic D., Mauric M., Stojevic Z., Mikulec Ž., Bajic M. and Mašek T. (2015). Production performance, meat composition and oxidative susceptibility in broiler chicken fed with different phenolic compounds. J. Sci. Food Agric. 95, 1172-1178.
Warshafsky S., Kamer R.S. and Sivak S.L. (1993). Effects of garlic on total serum cholesterol: A meta-analysis. Ann. Intern. Med. 119, 599-605.