Peripartum Injection of Vitamins (E and B12) and Trace Minerals (Selenium and Iron) in Holstein Dairy Cows: Effect on Milk Production and Composition, Body Condition Score and Serum Metabolites
الموضوعات :
S.R. Mousavi
1
(Department of Animal Science, Faculty of Agriculture, Ilam University, Ilam, Iran)
F. Fatahnia
2
(Department of Animal Science, Faculty of Agriculture, Ilam University, Ilam, Iran)
G. Taasoli
3
(Department of Animal Science Research, Chaharmahal Bakhtiari Agricultural and Natural Resources Research and Education Center, Agricultural Research, Education and Extension Organization (AREEO), Shahrekord, Iran)
Y. Mohammadi
4
(Department of Animal Science, Faculty of Agriculture, Ilam University, Ilam, Iran)
الکلمات المفتاحية: performance, dairy cow, mineral, Transition Period, vitamin,
ملخص المقالة :
The aim of this study was to determine the effects of injection of vitamin E and selenium, vitamin B12 and iron or their combination during the transition period on milk production and composition, body condition score (BCS) changes and serum metabolites of dairy cows. A total of 40 Holstein dairy cows (659±57.9 kg of body weight (BW)) were divided into four groups based on parity, BW and BCS and randomly assigned to experimental treatments. Experimental treatments were T1: injection of NaCl % 0.9 as control treatment (C), T2: injection of 3000 IU of vitamin E and 30 mg of selenium (ESe), T3: injection of 700 μg of vitamin B12 and 254 mg of iron (B12Fe) and T4: injection of 3000 IU of vitamin E and 30 mg of selenium plus 700 μg of vitamin B12 and 254 mg of iron (ESe+B12Fe). Injection of ESe, B12Fe or ESe + B12Fe had no effect on BCS and its changes (P>0.05). Milk production, 4% fat-corrected milk (FCM), energy-corrected milk (ECM) and milk fat, protein and lactose content and yield did not influence by injection of ESe, B12Fe or ESe + B12Fe (P>0.05). Experimental treatments had no effect on serum β-hydroxybutyrate (BHB), non-esterified fatty acids (NEFA), glucose, total protein, triglycerides, total cholesterol and HDL-cholesterol concentrations (P>0.05). It was concluded that injection of ESe, B12Fe or their combination during transition period had no effect on milk production and composition, BCS changes, and serum metabolites concentrations of Holstein dairy cows.
Abdelrahman M.M. and Kincaid R.L. (1995). Effect of selenium supplementation of cows on maternal transfer of selenium to fetal and newborn calves. J. Dairy Sci. 78, 625-630.
Akins M.S., Bertics S.J., Socha M.T. and Shaver R.D. (2013). Effects of cobalt supplementation and vitamin B12 injections on lactation performance and metabolism of Holstein dairy cows. J. Dairy Sci. 96, 1755-1768.
Andrieu S. (2008). Is there a role for organic trace element supplements in transition cow health? Vet. J. 176, 77-83.
Anwar F., Akhtar M.S., Lal C., Lodhi L.A., Ayaz M.M., Ahmad I., Farooq A.A. and Akhtar M. (2014). Effect of prepartum administration of selenium and vitamin E on subsequent postpartum performance in first calf Nili-Ravi buffalo heifers. J. Anim. Plant Sci. 24, 5-8.
AOAC. (2005). Official Methods of Analysis. 18th Ed. Association of Official Analytical Chemists, Arlington, Washington, DC., USA.
Atroshi F., Sankari S. and Lindstrom U.B. (1986). Somatic cell count and milk yield in relation to hemoglobin concentration in Finnish dairy goats. Vet. Res. Commun. 10, 57-63.
Baldi A. (2005). Vitamin E in dairy cows. Livest. Prod. Sci. 98, 117-122.
Baldi A., Savini G., Pinotti L., Monfaradini E., Cheli F. and Dellorto V. (2000). Effects of vitamin E and different energy sources on vitamin E status, milk quality and reproduction in transition cows. J. Vet. Med. A. 47, 599-608.
Bayril T., Yildiz A.S., Akdemir F., Yalcin C., Kose M. and Yilmaz O. (2015). The technical and financial effects of parenteral supplementation with selenium and vitamin E during late pregnancy and the early lactation period on the productivity of dairy cattle. Asian-Australasian J. Anim. Sci. 28, 1133-1139.
Bernabucci U., Ronchi B., Lacetera N. and Nardone A. (2005). Influence of body condition score on relationships between metabolic status and oxidative stress in periparturient dairy cows. J. Dairy Sci. 88, 2017-2026.
Bicalho M.L.S., Lima F.S., Ganda E.K., Foditsch C., Meira Jr E.B.S., Machado V.S., Teixeira A.G.V., Oikonomou G., Gilbert R.O. and Bicalho R.C. (2014). Effect of trace mineral supplementation on selected minerals, energy metabolites, oxidative stress, and immune parameters and its association with uterine diseases in dairy cattle. J. Dairy Sci. 97, 1-15.
Bourne N., Wathes D.C., Lawrence K.E., McGowan M. and Laven R.A. (2008). The effect of parenteral supplementation of vitamin E with selenium on the health and productivity of dairy cattle in the UK. Vet. J. 177, 381-387.
Calamari L., Petrera F., Abeni F. and Bertin G. (2011). Metabolic and hematological profiles in heat stressed lactating dairy cows fed diets supplemented with different selenium sources and doses. Lives. Sci. 142, 128-137.
Carlson D.B., McFadden J.W., D’Angelo A., Woodworth J.C. and Drackley J.K. (2007). Dietary L-carnitine affects periparturient nutrient metabolism and lactation in multiparous cows. J. Dairy Sci. 90, 3422-3441.
Cebra C.K., Heidel J.R., Crisman R.O. and Stang B.V. (2003). The relationship between endogenous cortisol, blood micronutrients, and neutrophil function in postparturient Holstein cows. J. Vet. Internal Med. 17, 902-907.
Chung Y.H., Brown N.E., Martinez C.M., Cassidy T.W. and Varga G.A. (2009). Effects of rumen-protected choline and dry propylene glycol on feed intake and blood parameters for Holstein dairy cows in early lactation. J. Dairy Sci. 92, 2729-2736.
Corah L.R. and Ives S. (1991). The effects of essential trace minerals on reproduction in beef cattle. Vet. Clin. North Am. Food Anim. Pract. 7, 41-57.
Costa A., Lopez-Villalobos N., Sneddon N.W., Shalloo L., Franzoi M., De Marchi M. and Penasa M. (2019). Invited review: Milk lactose-current status and future challenges in dairy cattle. J. Dairy Sci. 102, 5883-5898.
Daugherty S.R., Carstens G.E., Herd D.B., Barling K.S. and Randel R.D. (2002). Effects of prenatal and prebreeding trace mineral/vitamin E injections on calf health and reproductive performance of beef cows. Pp. 39-43 in 2002 / 2003
Beef Cattle Research in Texas. Texas A&M Univ., College Station, USA.
DeFrain J.M., Hippen A.R., Kalscheur K.F. and Jardon P.W. (2004). Feeding glycerol to transition dairy cows: Effects on blood metabolites and lactation performance. J. Dairy Sci. 87, 4195-4206.
Dhingra S. and Bansal M.P. (2006). Modulation of hyper-cholesterolemia-induced alterations in apolipoprotein B and HMG-CoA reductase expression by selenium supplementation. Chem. Biol. Interact. 161(1), 49-56.
Drackley J.K. (1999). ADSA foundation scholar award. Biology of dairy cows during the transition period: the final frontier? J. Dairy Sci. 82, 2259-2273.
Duffield T.F., Rabiee A.R. and Lean I.J. (2008). A meta-analysis of the impact of monensin in lactating dairy cattle. Part 1. Metabolic effects. J. Dairy Sci. 91, 1334-1346.
Duplessis M., Girard C.L., Santschi D.E., Lefebvre D.M. and Pellerin D. (2014). Milk production and composition, and body measurements of dairy cows receiving intramuscular injections of folic acid and vitamin B12 in commercial dairy herds. Lives. Sci. 167, 186-194.
Duplessis M., Lapierre H., Pellerin D., Laforest J.P. and Girard C.L. (2017). Effects of intramuscular injections of folic acid, vitamin B12, or both, on lactational performance and energy status of multiparous dairy cows. J. Dairy Sci. 100, 4051-4064.
Dutta-Roy A.K., Gordon M.J., Campbell F.M., Duthie G.C. and James W.P.T. (1994). Vitamin E requirements, transport, and metabolism: Role of a-tocopherol-binding proteins. J. Nut. Biochem. 5, 562-570.
Edmonson A.J., Lean I.J., Weaver L.D., Farver T. and Wester G. (1989). A body condition scoring chart for Holstein dairy cows. J. Dairy Sci. 72, 68-78.
Enjalbert F., Lebreton P. and Salat O. (2006). Effects of copper, zinc and selenium status on performance and health in commercial dairy and beef herds: Retrospective study. J. Anim. Physiol. Anim. Nutr. 90, 459-466.
Falkowska A., Minakowski D. and Tywonczuk J. (2000). The effect of supplementing rations with selenium and vitamin E on biochemical parameters in blood and performance of cows in the early stage of lactation. J. Anim. Feed Sci. 9, 271-282.
Furll M., Deniz A., Westphal B., Illing C. and Constable P.D. (2010). Effect of multiple intravenous injections of butaphosphan and cyanocobalamin on the metabolism of periparturient dairy cows. J. Dairy Sci. 93, 4155-4164.
Furugouri K., Miyata Y. and Shijimaya K. (1982). Ferritin in blood serum of dairy cows. J. Dairy Sci. 65, 1529-1534.
Galvao K.N., Flaminio M.J., Brittin S.B., Sper R., Fraga M., Caixeta L., Ricci A., Guard C.L., Butler W.R. and Gilbert R.O. (2010). Association between uterine disease and indicators of neutrophil and systemic energy status in lactating holstein cows. J. Dairy Sci. 93, 2926-2937.
Ganda E.K., Bisinotto R.S., Vasquez A.K., Teixeira A.G.V., Machado V.S., Foditsch C., Bicalho M., Lima F.S., Stephens L., Gomes M.S., Dias J.M. and Bicalho R.C. (2016). Effects of injectable trace mineral supplementation in lactating dairy cows with elevated somatic cell counts. J. Dairy Sci. 99, 1-11.
Girard C.L. and Matte J.J. (2005). Effects of intramuscular injections of vitamin B12 on lactation performance of dairy cows fed dietary supplements of folic acid and rumen-protected methionine. J. Dairy Sci. 88, 671-676.
Girard C.L., Lapierre H., Matte J.J. and Lobley G.E. (2005). Effects of dietary supplements of folic acid and rumen-protected methionine on lactational performance and folate metabolism of dairy cows. J. Dairy Sci. 88, 660-670.
Goff J.P., Kimura K. and Horst R.L. (2002). Effect of mastectomy on milk fever, energy, and vitamins A, E, and beta-carotene status at parturition. J. Dairy Sci. 85, 1427-1436.
Graulet B., Matte J.J., Desrochers A., Doepel L., Palin M.F. and Girard C.L. (2007). Effects of dietary supplements of folic acid and vitamin B12 on metabolism of dairy cows in early lactation. J. Dairy Sci. 90, 3442-3455.
Guyot H., Aliaoui H. and Rollin F. (2004). Trace elements deficiencies in the pathogenesis of respiratory distress syndrome in the mature newborn calf. Pp. 1-20 in Proc. 23th World Buiatrics Congr., Quebec, Canada.
Hammon D.S., Evjen I.M., Dhiman T.R., Goff J.P. and Walters J.L. (2006). Neutrophil function and energy status in Holstein cows with uterine health disorders. Vet. Immunol. Immunopathol. 113, 21-29.
Hansen S.L. and Spears J.W. (2009). Bioaccessibility of iron from soil is increased by silage fermentation. J. Dairy Sci. 92, 2896-2905.
Hayirli A., Grummer R.R., Nordheim E.V. and Crump P.M. (2002). Animal and dietary factors affecting feed intake during the prefresh transition period in Holsteins. J. Dairy Sci. 85, 3430-3443.
Huzzey J.M., Veira D.M., Weary D.M. and von Keyserlingk M.A. (2007). Prepartum behavior and dry matter intake identify dairy cows at risk for metritis. J. Dairy Sci. 90, 3220-3233.
Jenkins T.C. and McGuire M.A. (2006). Major advances in nutrition: Impact on milk composition. J. Dairy Sci. 89, 1302-1310.
Juniper D.T., Phipps R.H., Ramos-Moralesa E. and Bertin G. (2009). Effect of high dose selenium enriched yeast diets on the distribution of total selenium and selenium species within lamb tissues. Lives. Sci. 122, 63-67.
Khorsandi S., Riasi A., Khorvash M., Mahyari S.A., Mohammadpanah F. and Ahmadi F. (2016). Lactation and reproductive performance of high producing dairy cows given sustained-release multi-trace element/vitamin ruminal bolus under heat stress condition. Livest. Sci. 187, 146-150.
Kincaid R.L. and Socha M. (2004). Inorganic versus complexed trace mineral supplements on performance of dairy cows. Prof. Anim. Sci. 20, 66-73.
Kincaid R.L. and Socha M.T. (2007). Effect of cobalt supplementation during late gestation and early lactation on milk and serum measures. J. Dairy Sci. 90, 1880-1886.
Kincaid R.L., Lefebvre L.E., Cronrath J.D., Socha M.T. and Johnson A.B. (2003). Effect of dietary cobalt supplementation on cobalt metabolism and performance of dairy cattle. J. Dairy Sci. 86, 1405-1414.
Kojouri G.A. (2002). A study on relationship between concentrations of selenium, copper, manganese, zinc and iodine in soil, plant and animal in Bakhtiari, provience. Final Project Technical Research Council of Islamic Republic of Iran, Tehran, Iran.
Kreipe L., Deniz A., Bruckmaier R.M. and Van Dorland H.A. (2011). First report about the mode of action of combined butafosfan and cyanocobalamin on hepatic metabolism in non-ketotic early lactating cows. J. Dairy Sci. 94, 4904-4914.
Kushner I. (1982). The phenomenon of the acute phase response. Ann. New York Acad. Sci. 389, 39-48.
Liu Z.L., Yang D.P., Chen P., Dong W.X. and Wang D.M. (2008). Supplementation with selenium and vitamin E improves milk fat depression and fatty acid composition in dairy cows fed fat diet. Asian-Australasian J. Anim. Sci. 21, 838-844.
Machado V.S., Bicalho M.L.S., Pereira R.V., Caixeta L.S., Knauer W.A., Oikonomou G., Gilbert M.R.O. and Bicalho R.C. (2013). Effect of an injectable trace mineral supplement containing selenium, copper, zinc, and manganese on the health and production of lactating Holstein cows. Vet. J. 197, 451-456.
Machado V.S., Oikonomou G., Lima S.F., Bicalhoa M.L.S., Kacar C., Foditsch C., Felippeb M.J., Gilbert R.O. and Bicalho R.C. (2014). The effect of injectable trace minerals (selenium, copper, zinc, and manganese) on peripheral blood leukocyte activity and serum superoxide dismutase activity of lactating Holstein cows. Vet. J. 200, 299-304.
Martinez N., Risco C.A., Lima F.S., Bisinotto R.S., Greco L.F., Ribeiro E.S., Maunsell F., Galvao K. and Santos J.E. (2012). Evaluation of peripartal calcium status, energetic profile, and neutrophil function in dairy cows at low or high risk of developing uterine disease. J. Dairy Sci. 95, 7158-7172.
McDowell L.R. (2000). Vitamins in Animal and Human Nutrition. Iowa State University Press, Ames, Iowa, USA.
Moallem U., Katz M., Arieli A. and Lehrer H. (2007). Effects of peripartum propylene glycol or fats differing in fatty acid profiles on feed intake, production, and plasma metabolites in dairy cows. J. Dairy Sci. 90, 3846-3856.
Moeini M.M., Karami H. and Mikaeili E. (2009). Effect of selenium and vitamin E supplementation during the late pregnancy on reproductive indices and milk production in heifers. Anim. Reprod. Sci. 114, 109-114.
Moghimi-Kandelousi M., Alamouti A.A., Imani M. and Zebeli Q. (2020). A meta-analysis and meta-regression of the effects of vitamin E supplementation on serum enrichment, udder health, milk yield, and reproductive performance of transition cows. J. Dairy Sci. 103, 6157-6166.
Mosley S.A., Shahin A.M., Williams J., McGuire M.A. and McGuire M.K. (2007). Supplemental conjugated linoleic acid consumption does not influence milk macronutrient contents in all healthy lactating women. Lipids. 42, 723-729.
NRC. (2001). Nutrient Requirements of Dairy Cattle. 7th Ed. National Academy Press, Washington, DC., USA.
Oetzel G.R. (2013). Oral calcium supplementation in peripartum dairy cows. Vet. Clin. North Am. Food Anim. Pract. 29, 447-455.
Pereira P.A.S., Silveira P., Montagner A., Schneider E., Schmitt V.R., Rabassa L.F.M., Pfeifer F.A.B., Del Pino M., Pulga M.E. and Correa M.N. (2013). Effect of butaphosphan and cyanocobalamin on postpartum metabolism and milk production in dairy cows. Animal. 7(7), 1143-1147.
Pilarczyk B., Jankowiak D., Tomza-Marciniak A., Pilarczyk R., Sablik P., Drozd R., Tylkowska A. and Skolmowska M. (2012). Selenium concentration and glutathione peroxidase (GSH-Px) activity in serum of cows at different stages of lactation. Biol. Trace Elem. Res. 147, 91-96.
Pires J.A., Pescara J.B. and Grummer R.R. (2007). Reduction of plasma NEFA concentration by nicotinic acid enhances the response to insulin in feed restricted Holstein cows. J. Dairy Sci. 90, 4635-4642.
Pontes G.C.S., Monteiro P.L.J., Prata A.B., Guardieiro M.M., Pinto D.A.M., Fernandes G.O., Wiltbank M.C., Santos J.E.P. and Sartori R. (2015). Effect of injectable vitamin E on incidence of retained fetal membranes and reproductive performance of dairy cows. J. Dairy Sci. 98, 2437-2449.
Preynat A., Lapierre H., Thivierge M.C., Palin M.F., Matte J.J., Desrochers A. and Girard C.L. (2009). Effects of supplements of folic acid, vitamin B12, and rumen-protected methionine on whole body metabolism of methionine and glucose in lactating dairy cows. J. Dairy Sci. 92, 677-689.
Remppis S., Steingass H., Gruber L. and Schenkel H. (2011). Effects of energy intake on performance, mobilization and retention of body tissue, and metabolic parameters in dairy cows with special regard to effects of pre-partum nutrition on lactation: A review. Asian-Australasian J. Anim. Sci. 24, 540-572.
Rensis F.D. and Scaramuzzi R.J. (2003). Heat stress and seasonal effects on reproduction in the dairy cow-a review. Theriogenology. 60, 1139-1151.
Roberts T., Chapinal N., LeBlanc S.J., Kelton D.F., Dubuc J. and Duffield T.F. (2012). Metabolic parameters in transition cows as indicators for early-lactation culling risk. J. Dairy Sci. 95, 3057-3063.
Roche J.R., Friggens N.C., Kay J.K., Fisher M.W., Stafford K.J. and Berry D.P. (2009). Invited review: Body condition score and its association with dairy cow productivity, health, and welfare. J. Dairy Sci. 92, 5769-801.
Roche J.R., Kay J.K., Friggens N.C., Loor J.J. and Berry D.P. (2013). Assessing and managing body condition score for the prevention of metabolic disease in dairy cows. Vet. Clin. Food Anim. Pract. 29, 323-336.
Rollin E., Berghaus R.D., Rapnicki P., Godden S.M. and Overton M.W. (2010). The effect of injectable butaphosphan and cyanocobalamin on postpartum serum β-hydroxybutyrate, calcium, and phosphorus concentrations in dairy cattle. J. Dairy Sci. 93, 978-987.
Santos N.W., Yoshimura E.H., Machado E., Matumoto-Pintro P.T., Montanher P.F., Visentainer J.V., Dos Santos G.T. and Zeoula L.M. (2016). Antioxidant effects of a propolis extract and vitamin E in blood and milk of dairy cows fed diet containing flaxseed oil. Livest. Sci. 191, 132-138.
Schafers S., von Soosten D., Meyer U., Drong C., Frahm J., Kluess J., Raschka C., Rehage J., Troscher A., Pelletier W. and Danicke S. (2017). Influence of conjugated linoleic acid and vitamin E on performance, energy metabolism, and change of fat depot mass in transitional dairy cows. J. Dairy Sci. 100, 3193-3208.
Smith K.L., Hogan J.S. and Weiss W.P. (1997). Dietary vitamin E and selenium affect mastitis and milk quality. J. Anim. Sci. 75, 1659-1665.
Sordillo L.M. (2005). Factors affecting mammary gland immunity and mastitis susceptibility. Livest. Sci. 98, 89-99.
Sordillo L.M. and Aitken S.L. (2009). Impact of oxidative stress on the health and immune function of dairy cattle. Vet. Immunol. Immunopathol. 128, 104-109.
Spears J.W. (2003). Trace mineral bioavailability in ruminants. J. Nutr. 133, 506-1509.
Spears J.W. and Weiss W.P. (2008). Role of antioxidants and trace elements in health and immunity of transition dairy cows. Vet. J. 176, 70-76.
Thomas J.W., Okamoto M., Jacobson W.C. and Moore L.A. (1954). A study of hemoglobin levels in the blood of young dairy calves and the alleviation of anemia by iron. J. Dairy Sci. 37, 805-812.
Tomlinson D.J., Socha M.T. and DeFrain J.M. (2008). Role of trace minerals in the immune system. Pp.
39-52 in Proc. Penn State Dairy Cattle Nutr. Workshop., Grantville, Pennsylvania.
Tyrrell H.F. and Reid J.T. (1965). Prediction of the energy value of cow milk. J. Dairy Sci. 48, 1215-1223.
Underwood E.J. and Suttle N.F. (1999). The Mineral Nutrition of Livestock. CABI Publishing, New York.
Van Soest P.J., Robertson J.B. and Lewis B.A. (1991). Methods for dietary fiber, neutral detergent fiber, and non-starch polysaccharides in relation to animal nutrition. J. Dairy Sci. 74, 3593-3597.
Vasiľ M., Zigo F., Elečko J., Zigova M. and Farkašova Z. (2017). Effect of peroral supplementation with selenium and vitamin E during late pregnancy on udder health and milk quality in dairy cows. Slovak J. Food Sci. 11, 535-538.
Wang C., Liu Q., Yang W.Z., Dong Q., Yang X.M., He D.C., Zhang P., Dong K.H. and Huang Y.X. (2009). Effects of selenium yeast on rumen fermentation, lactation performance and feed digestibilities in lactating dairy cows. Livest. Sci. 126, 239-244.
Weerathilake W.A.D.V., Brassington A.H., Williams S.J., Kwong W.Y., Sinclair L.A. and Sinclair K.D. (2018). Added dietary cobalt or vitamin B12, or injecting vitamin B12 does not improve performance or indicators of ketosis in pre- and post-partum Holstein-Friesian dairy cows. Animal. 5, 1-10.
Weiss W.P. and Ferreira G. (2006). Water soluble vitamins for dairy cattle. Pp 51-63 in Proc. Tristate Dairy Nutr. Conf., Fort Wayne, Indiana.
Weiss W.P. and Spears J.W. (2006). Vitamin and trace mineral effects on immune function of ruminants. Pp. 473-496. in Ruminant Physiology. K. Sejrsen, T. Hvelplund and M.O. Nielsen, Eds. Wageningen Academic Publishers, Utrecht, The Netherlands.
Weiss W.P., Pinos-Rodríguez J.M. and Socha M.T. (2010). Effects of feeding supplemental organic iron to late gestation and early lactation dairy cows. J. Dairy Sci. 93, 2153-2160.
Xin Z., Waterman D.F., Hemken R.W. and Harmon R.J. (1993). Copper status and requirement during the dry period and early lactation in multiparous Holstein cows. J. Dairy Sci. 76, 2711-2716.
Yang K.C., Lee L.T., Lee Y.S., Huang H.Y., Chen C.Y. and Huang K.C. (2010). Serum selenium concentration is associated with metabolic factors in the elderly: A cross-sectional study. Nutr. Metab. 7, 38-47.
