α-Amylase inhibition and antioxidant activity of Singhnad Guggul in vitro

الموضوعات : مجله گیاهان دارویی

اشوک کومار ¹ (گروه فارماکوگنوزی، سری کا وی کالج داروسازی، چیکبالاپور، کاراناتاکا، هند؛)
سالیمولا خان ² (گروه فارماکوگنوزی، کالج داروسازی مانیپال، مانیپال، کاراناتاکا، هند؛)
گوپی ستی ساران ³ (گروه فارماکوگنوزی، سری کا وی کالج داروسازی، چیکبالاپور، کاراناتاکا، هند؛)
ناوین کومار ⁴ (گروه فارماکوگنوزی، سری کا وی کالج داروسازی، چیکبالاپور، کاراناتاکا، هند؛)
لوکانت وی ⁵ (گروه فارماکوگنوزی، سری کا وی کالج داروسازی، چیکبالاپور، کاراناتاکا، هند؛)

تاريخ الإرسال : 25 الخميس , ذو القعدة, 1433 تاريخ التأكيد : 14 الخميس , صفر, 1434 تاريخ الإصدار : 22 الإثنين , شعبان, 1434

الکلمات المفتاحية: &alpha, -amylase, Singhnad Guggul, Chelating assay,

ملخص المقالة :

Background & Aim: Singhnad Guggulu is a traditional Ayurvedic formula for detoxifying and rejuvenating the joints. The present study was to investigate the α-amylase inhibition and antioxidant activities of aqueous extract of Singhnad Guggul (AESG). Experimental: α-Amylase inhibition assay by dinitro-salicylic acid method and antioxidant activity by ferric chelating and ferrous reducing assay. Results: AESG indicated that potent α-amylase inhibition activity (IC50= 84.00 µg/ml). AESG also showed ferric chelating and ferrous reducing activities. Recommended applications/industries: Our studies showed that Singhnad Guggulu possess alpha- amylase and antioxidant properties.

المصادر:

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