Catalyst free synthesis of pyrrole derivatives using multicomponent reactions

الموضوعات : Iranian Journal of Organic Chemistry

Samanehsadat Sharifi ¹ , Narjes Haeizadeh ²

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تاريخ الإرسال : 27 الإثنين , محرم, 1445 تاريخ التأكيد : 27 الإثنين , محرم, 1445 تاريخ الإصدار : 11 الإثنين , شوال, 1444

الکلمات المفتاحية: Three-component reaction, Primary Amines, Pyrrole, green chemistry, N-formylmorpholine,

ملخص المقالة :

A convenient and efficient procedure for the synthesis of substituted pyrroles has been reported based on three component reactions of primary amines and activated acetylenic compounds in the presence of N-formylmorpholine as a green solvent. The above synthetic procedure offers rapid access to novel and diversely substituted pyrrole derivatives.