Synthesis of urea derivatives using multicomponent reactions of activated acetylene

الموضوعات : Iranian Journal of Organic Chemistry

Seyyed Jalal Shams Najafi ¹ , Maryam Ghazvini ² , Atefeh Navabi ³

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تاريخ الإرسال : 27 الأربعاء , جمادى الأولى, 1444 تاريخ التأكيد : 27 الأربعاء , جمادى الأولى, 1444 تاريخ الإصدار : 03 الإثنين , محرم, 1444

الکلمات المفتاحية: Alcohol, Esterification, N-formylmorpholine, Acid chlorides, Potasium thiocyanate,

ملخص المقالة :

urea derivatives are obtained in good to excellent yields by proceeding through a simple, mild, and efficientprocedure utilizing activated acetylens, primary amines and isocyanates in the presence of catalytic amount of Nformylmorpholine under solvent-free conditions.