Green synthesis of oxazole triazole derivatives: Application of Fe3O4@MWCNT MNCs

الموضوعات : Iranian Journal of Organic Chemistry

Samaneh Sadat Sharifi ¹ , Seyyed Jalal Shams Najafi ² , Majid Ghazanfarpour ³

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تاريخ الإرسال : 27 الأربعاء , جمادى الأولى, 1444 تاريخ التأكيد : 27 الأربعاء , جمادى الأولى, 1444 تاريخ الإصدار : 03 الإثنين , محرم, 1444

الکلمات المفتاحية: Ammonium thiocyanate, Fe3O4@MWCNT MNCs, 1, 3-oxazole, Isothiocyanates, Alkyl (aryl) isothiocyanates,

ملخص المقالة :

1,3-oxazole derivatives were prepared via multicomponent reaction of α-bromo ketones, acid chlorides andammonium thiocyanate in the presence of catalytic amount of Fe3O4@MWCNT MNCs in water at 50oC in good yields. Also, the reaction of alkyl (aryl) isothiocyanates and -bromo ketones in the presence of catalytic amount of Fe3O4 MNPs in water at 50oC are investigated. The catalyst was reused five times with minor decrease in its catalytic activity. In addition, high yields, easy procedure, easy separation of catalyst from the mixture of reactions are the advantages of these reactions.