Green synthesis of functionalized oxaphosphole-1,2,4-triazoles: Investigation of biological Activity

الموضوعات : Iranian Journal of Organic Chemistry

Narjes Haerizadeh ¹ , Maryam Koohi ²

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تاريخ الإرسال : 27 الأربعاء , جمادى الأولى, 1444 تاريخ التأكيد : 27 الأربعاء , جمادى الأولى, 1444 تاريخ الإصدار : 03 الإثنين , محرم, 1444

الکلمات المفتاحية: Ammonium thiocyanate, Esterification, N-formylmorpholine, Acid chlorides, 3-Hydroxy-2-butanone,

ملخص المقالة :

The reaction of activated acetylenic compounds with triphenylphosphine (Ph3P) in the presence of isatins or itsderivatives and hydrazonoyl chlorides led to oxaphosphole-1,2,4-triazole derivatives in good yields. Also, antioxidant property of some prepared compounds was investigated using diphenyl-picrylhydrazine (DPPH) radical trapping experiment.