ﺑﺮرﺳﯽ ﺷﯿﻮع سرمی ﺑﯿﻤﺎری اﺳﻬﺎل وﯾﺮوﺳﯽ ﮔﺎوی در جمعیت گاوان استان گلستان به روش اﻻﯾﺰا
محورهای موضوعی :
آسیب شناسی درمانگاهی دامپزشکی
عارف امانبائی
1
,
جلال شایق
2
,
محمدرضا ولیلو
3
,
حانیه‌السادات تقیان
4
1 - دانش‌آموخته گروه دامپزشکی، دانشکده دامپزشکی و کشاورزی، واحد شبستر، دانشگاه آزاد اسلامی، شبستر، ایران.
2 - استادیار گروه دامپزشکی، دانشکده دامپزشکی و کشاورزی، واحد شبستر، دانشگاه آزاد اسلامی، شبستر، ایران.
3 - استادیار گروه پاتوبیولوژی، دانشکده دامپزشکی، علوم پزشکی تبریز، دانشگاه آزاد اسلامی، تبریز، ایران.
4 - دانشجوی گروه دامپزشکی، دانشکده دامپزشکی و کشاورزی، واحد شبستر، دانشگاه آزاد اسلامی، شبستر، ایران
تاریخ دریافت : 1401/10/11
تاریخ پذیرش : 1402/02/20
تاریخ انتشار : 1402/05/01
کلید واژه:
استان گلستان,
الایزا,
شیوع,
اسهال ویروسی گاو,
چکیده مقاله :
بیماری اسهال ویروسی گاوان (bovine viral diarrhea; BVD) به عنوان یکی از معضلات صنعت دامپروری در جهان به شمار می رود که در صورت عدم کنترل آن، می‌تواند خسارات اقتصادی قابل توجهی را به وجود آورد. ریشه کنی این بیماری به دلیل وجود دام های دارای عفونت پایدار، نیازمند مطالعات سرولوژیکی و مولکولی است. هدف از انجام مطالعه حاضر، بررسی شیوع سرمی بیماری فوق در گاوهای استان گلستان بود. به این منظور از 380 رأس گاو منتخب مربوط به گاوداری های صنعتی و سنتی 6 شهرستان استان گلستان، به صورت تصادفی، نمونه سرمی تهیه شده و از نظر وجود پادتن علیه ویروس BVD، توسط کیت اختصاصی مربوطه، به روش الایزا مورد آزمایش قرار گرفت. یافته های حاصله، شیوع 68/18 درصدی پادتن ضد ویروس BVD در سرم های اخذشده را نشان داد. بیشترین شیوع سرمی مذکور مربوط به شهرستان بندرترکمن و کمترین آن مربوط به شهرستان علی آباد ثبت شد. میزان شیوع سرمی بیماری اسهال ویروسی گاوان در گاوداری های سنتی بیشتر از گاوداری های صنعتی بود (05/0p<) و بین افزایش سن و تعداد شکم زایش با افزایش موارد مثبت ابتلا به بیماری ارتباط معنی داری وجود نداشت. شیوع سرمی بالای بیماری اسهال ویروسی گاوان در گاوداری های استان گلستان بر گستردگی آلودگی و اهمیت اقتصادی کنترل این بیماری اشاره دارد. به نظر می رسد که تأکید بر تغییر رویکرد سیستم پرورش مبنی بر صنعتی کردن پرورش دام و اتخاذ روش های مدیریتی صحیح می تواند در کنترل بیماری مذکور در کنار سایر تدابیر پیشگیرانه کمک کند.
چکیده انگلیسی:
Bovine Viral Diarrhea is considered as one of the difficulties in industrial livestock whole world. If it went out of control, can causes significant economic losses. The eradication of the disease requires serological and molecular studies due to the presence of animals with persist infection. This study’s purpose is prevalence assessment of this disease in Golestan province. In order to do this, serum samples were taken from 200 cows (which) selected from industrial and traditional farms in 6 cities of the Golestan province randomly and they were tested for the presence of antibodies against BVDV by standard ELISA kits. The results showed that the prevalence of BVD antibodies in obtained serums is 22/92 percent. The most prevalence is related to the Bandar-e-Turkman county and the least prevalence is related to the Aliabad county. The prevalence of the disease in industrial farming system was more than traditional one (p<0.1) and there was a significant relationship between increasing age and number of claves with increasing antibody titer. Thus, the high serum prevalence of infection in farms in Golestan province refers to spread of pollution and economical importance of controlling the disease. Emphasis on changing the approach to livestock industrialization can help controlling the disease beside other preventive measures.
منابع و مأخذ:
Bahonar, A.R., Jahromi, O.N., Omidvarian, M.J., Najjar, E., Shokri, M.R. and Mirzaie, K. (2011). Bovine viral diarrhea in Qazvin Province (Iran): a seroprevalence study. Journal of Veterinary Research, 66(4): 319-374. [In Persian]
Burgstaller, J., Obritzhauser, W., Kuchling, S., Kopacka, I., Pinior, B. and Köfer, J. (2016). The effect of bovine viral diarrhoea virus on fertility in dairy cows: two case-control studies in the province of Styria, Austria. Berliner und Münchener Tierärztliche Wochenschrift, 129(3/4): 103-110.
Casaubon, J., Vogt, H.R., Stalder, H., Hug, C. and Ryser-Degiorgis, M.P. (2012). Bovine viral diarrhea virus in free-ranging wild ruminants in Switzerland: low prevalence of infection despite regular interactions with domestic livestock. BMC Veterinary Research, 8(1): 1-14.
Davasaz Tabrizi, A., Zare, P., Davoudi, Y. and Mosaferi, S. (2011). Prevalence of bovine viral diarrhea disease investigated with indirect ELISA method in dairy Holstein cows of Tabriz region. Veterinary Clinical Pathology the Quarterly Scientific Journal, 5(17): 1067-1073. [In Persian]
Deng, M., Ji, S., Fei, W., Raza, S., He, C., Chen, Y., Chen, H. and Guo, A. (2015). Erratum: Prevalence study and genetic typing of bovine viral diarrhea virus (BVDV) in four bovine species in China. PloS one, 10(4): e0121718.
Hematzahed, F., Korouji, G.H.A., Kargar, P. and Rohani, M. (2001). Survey of bovine viral diarrhea in Chaharmahal prvince. Veterinary Research Journal. 56: 85-92. [In Persian]
Houe, H., (1999). Epidemiological features and economical importance of bovine virus diarrhea virus (BVDV) infections. Veterinary Microbiology, 64(2-3): 89-107.
Jokar, M., Rahmanian, V., Farhoodi, M., Abdous, A., Shams, F. and Karami, N. (2021). Seroprevalence of bovine viral diarrhea virus (BVDV) infection in cattle population in Iran: a systematic review and meta-analysis. Tropical Animal Health and Production, 53(5): 449. [In Persian]
Kelling, C.L., Steffen, D.J., Cooper, V.L., Higuchi, D.S. and Eskridge, K.M. (2002). Effect of infection with bovine viral diarrhea virus alone, bovine rotavirus alone, or concurrent infection with both on enteric disease in gnotobiotic neonatal calves. American Journal of Veterinary Research, 63(8): 1179-1186.
Kozasa, T., Tajima, M., Yasutomi, I., Sano, K., Ohashi, K. and Onuma, M. (2005). Relationship of bovine viral diarrhea virus persistent infection to incidence of diseases on dairy farms based on bulk tank milk test by RT-PCR. Veterinary Microbiology, 106(1-2): 41-47.
Liu, L., Xia, H., Wahlberg, N., Belák, S. and Baule, C. (2009). Phylogeny, classification and evolutionary insights into pestiviruses. Virology, 385(2): 351-357.
Mirshamsy, H., Shafyi, A. and Bahrami, S. (1970). The occurrence of bovine virus diarrhea/mucosal disease in Iran. Archive of Razi Institute, 22: 194-201. [In Persian]
Nettleton, P.F., Gilmour, J.S., Herring, J.A. and Sinclair, J.A. (1992). The production and survival of lambs persistently infected with border disease virus. Comparative Immunology, Microbiology and Infectious Diseases, 15(3): 179-188.
Ridpath, J.F. (2010). Bovine viral diarrhea virus: global status. Veterinary Clinics: Food Animal Practice, 26(1): 105-121.
Riley, J.M., Peel, D.S., Raper, K.C. and Hurt, C. (2019). Invited review: economic consequences of beef cow-calf disease mismanagement: bovine viral diarrhea virus. Applied Animal Science, 35(6): 606-614.
Shayegh, J., Pakzeh, N., Mohammadzadeh, M. and Bagherian Zakaria, S. (2019). Concise Review of Animal Viral Diseases. 2nd ed., Tarrahe Danesh, pp: 113- 118. [In Persian]
Smirnova, N.P., Webb, B.T., McGill, J.L., Schaut, R.G., Bielefeldt-Ohmann, H., Van Campen, et al., (2014). Induction of interferon-gamma and downstream pathways during establishment of fetal persistent infection with bovine viral diarrhea virus. Virus Research, 183: 95-106.
Talebkhan Garoussi, M., Haghparast, A.R. and Rafati, M.S. (2011). The prevalence of bovine viral diarrhea virus in persistently infected cows in industrial dairy herds in suburb of Mashhad-Iran Int. Iranian Journal of Veterinary Medicine, 5: 198-203. [In Persian]
Tautz, N., Tews, B.A. and Meyers, G. (2015). The molecular biology of pestiviruses. Advances in Virus Research, 93: 47-160.
Yeşilbağ, K., Alpay, G. and Becher, P. (2017). Variability and global distribution of subgenotypes of bovine viral diarrhea virus. Viruses, 9(6): 128.
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Bahonar, A.R., Jahromi, O.N., Omidvarian, M.J., Najjar, E., Shokri, M.R. and Mirzaie, K. (2011). Bovine viral diarrhea in Qazvin Province (Iran): a seroprevalence study. Journal of Veterinary Research, 66(4): 319-374. [In Persian]
Burgstaller, J., Obritzhauser, W., Kuchling, S., Kopacka, I., Pinior, B. and Köfer, J. (2016). The effect of bovine viral diarrhoea virus on fertility in dairy cows: two case-control studies in the province of Styria, Austria. Berliner und Münchener Tierärztliche Wochenschrift, 129(3/4): 103-110.
Casaubon, J., Vogt, H.R., Stalder, H., Hug, C. and Ryser-Degiorgis, M.P. (2012). Bovine viral diarrhea virus in free-ranging wild ruminants in Switzerland: low prevalence of infection despite regular interactions with domestic livestock. BMC Veterinary Research, 8(1): 1-14.
Davasaz Tabrizi, A., Zare, P., Davoudi, Y. and Mosaferi, S. (2011). Prevalence of bovine viral diarrhea disease investigated with indirect ELISA method in dairy Holstein cows of Tabriz region. Veterinary Clinical Pathology the Quarterly Scientific Journal, 5(17): 1067-1073. [In Persian]
Deng, M., Ji, S., Fei, W., Raza, S., He, C., Chen, Y., Chen, H. and Guo, A. (2015). Erratum: Prevalence study and genetic typing of bovine viral diarrhea virus (BVDV) in four bovine species in China. PloS one, 10(4): e0121718.
Hematzahed, F., Korouji, G.H.A., Kargar, P. and Rohani, M. (2001). Survey of bovine viral diarrhea in Chaharmahal prvince. Veterinary Research Journal. 56: 85-92. [In Persian]
Houe, H., (1999). Epidemiological features and economical importance of bovine virus diarrhea virus (BVDV) infections. Veterinary Microbiology, 64(2-3): 89-107.
Jokar, M., Rahmanian, V., Farhoodi, M., Abdous, A., Shams, F. and Karami, N. (2021). Seroprevalence of bovine viral diarrhea virus (BVDV) infection in cattle population in Iran: a systematic review and meta-analysis. Tropical Animal Health and Production, 53(5): 449. [In Persian]
Kelling, C.L., Steffen, D.J., Cooper, V.L., Higuchi, D.S. and Eskridge, K.M. (2002). Effect of infection with bovine viral diarrhea virus alone, bovine rotavirus alone, or concurrent infection with both on enteric disease in gnotobiotic neonatal calves. American Journal of Veterinary Research, 63(8): 1179-1186.
Kozasa, T., Tajima, M., Yasutomi, I., Sano, K., Ohashi, K. and Onuma, M. (2005). Relationship of bovine viral diarrhea virus persistent infection to incidence of diseases on dairy farms based on bulk tank milk test by RT-PCR. Veterinary Microbiology, 106(1-2): 41-47.
Liu, L., Xia, H., Wahlberg, N., Belák, S. and Baule, C. (2009). Phylogeny, classification and evolutionary insights into pestiviruses. Virology, 385(2): 351-357.
Mirshamsy, H., Shafyi, A. and Bahrami, S. (1970). The occurrence of bovine virus diarrhea/mucosal disease in Iran. Archive of Razi Institute, 22: 194-201. [In Persian]
Nettleton, P.F., Gilmour, J.S., Herring, J.A. and Sinclair, J.A. (1992). The production and survival of lambs persistently infected with border disease virus. Comparative Immunology, Microbiology and Infectious Diseases, 15(3): 179-188.
Ridpath, J.F. (2010). Bovine viral diarrhea virus: global status. Veterinary Clinics: Food Animal Practice, 26(1): 105-121.
Riley, J.M., Peel, D.S., Raper, K.C. and Hurt, C. (2019). Invited review: economic consequences of beef cow-calf disease mismanagement: bovine viral diarrhea virus. Applied Animal Science, 35(6): 606-614.
Shayegh, J., Pakzeh, N., Mohammadzadeh, M. and Bagherian Zakaria, S. (2019). Concise Review of Animal Viral Diseases. 2nd ed., Tarrahe Danesh, pp: 113- 118. [In Persian]
Smirnova, N.P., Webb, B.T., McGill, J.L., Schaut, R.G., Bielefeldt-Ohmann, H., Van Campen, et al., (2014). Induction of interferon-gamma and downstream pathways during establishment of fetal persistent infection with bovine viral diarrhea virus. Virus Research, 183: 95-106.
Talebkhan Garoussi, M., Haghparast, A.R. and Rafati, M.S. (2011). The prevalence of bovine viral diarrhea virus in persistently infected cows in industrial dairy herds in suburb of Mashhad-Iran Int. Iranian Journal of Veterinary Medicine, 5: 198-203. [In Persian]
Tautz, N., Tews, B.A. and Meyers, G. (2015). The molecular biology of pestiviruses. Advances in Virus Research, 93: 47-160.
Yeşilbağ, K., Alpay, G. and Becher, P. (2017). Variability and global distribution of subgenotypes of bovine viral diarrhea virus. Viruses, 9(6): 128.
