مروری بر رخداد نئوسپوروزیس گاوی در ایران
محورهای موضوعی : آسیب شناسی درمانگاهی دامپزشکیاحمد نعمت الهی بنابی 1 , نگار فروزانفر 2
1 - استاد گروه پاتوبیولوژی، دانشکده دامپزشکی، دانشگاه تبریز، تبریز، ایران.
2 - دانش‌آموخته دکترای حرفه‌ای دامپزشکی، دانشکده دامپزشکی، دانشگاه تبریز، تبریز، ایران.
کلید واژه: ایران, گاو, نئوسپوروزیس, مطالعات مروری,
چکیده مقاله :
نئوسپوروزیس (Neosporosis) بیماری است که توسط تک یاخته ای به نام نئوسپورا کانینوم (Neospora caninum) ایجاد می‌شود و با وقوع سقط جنین در گاو و نیز ایجاد فلج عصبی و عضلانی اندام های مختلف، مخصوصاً فلجی اندام های خلفی در سگ شناخته می‌شود. بیماری نئوسپوروزیس برای اولین بار در سال 1984 در نروژ مورد شناسائی قرار گرفت. سگ تنها میزبان اصلی و همچنین میزبان واسط تک‌یاخته نئوسپورا کانینوم می‌باشد، ولی آلودگی در گاو، گوسفند، بز، اسب و گوزن نیز دیده می‌شود. اهمیت بیماری نئوسپوروزیس در ارتباط با ایجاد سقط جنین در نشخوارکنندگان (مخصوصاً گاو) و خسارات اقتصادی ایجادشده در دامداری‌های صنعتی می باشد که این مسئله باعث شده، مطالعات فراوانی در ایران و جهان در مورد آن انجام پذیرد. برای اولین بار گزارش بررسی بیماری مذکور در ایران در سال 2004 انجام گرفته و از آن سال به بعد، مطالعات فراوانی در مورد آن انجام شده است. در مقاله مروری حاضر، سعی شده است که ضمن معرفی تک یاختهء عامل بیماری و سیر تکاملی آن و روش های تشخیص بیماری، مروری بر مطالعات انجام‌یافته در مورد این بیماری در ایران، از ابتدا تا به امروز، ارائه شود.
چکیده انگلیسی:
Neosporosis is a disease caused by a protozoan called Neospora caninum, which is characterized by abortion in cows and nerve and muscle paralysis of various organs, especially the hind limbs of dogs. This disease was identified for the first time in 1984 in Norway. The dog is the only definitive host and also the intermediate host of protozoa and contamination can also be seen in cattle, sheep, goats, horses, and deer. The importance of neosporosis disease is related to causing abortion in ruminants (especially cows) and the economic losses caused in industrial livestock farming, which has caused many studies to be conducted in Iran and rest of the world. The disease was first reported in Iran in 2004, and since that year, many studies have been conducted about it. In this review article, an attempt has been made to introduce the protozoa that causes the disease and its evolution, as well as the methods of diagnosing the disease, and provide an overview of the studies conducted on this disease in Iran, from the beginning to the present day.
منابع و مأخذ:
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Adhami, G., Hoghooghi, R. and Dalimi, A. (2014). The seroepidemiological investigation into Neospora caninum in cattle in Sanandaj, Kordestan Province. Journal of Veterinary Microbiology, 10(2): 83-92. [In Persian]
Alipour, M., Rahimi, E. and Shakerian, A. (2019). Study the prevalence of Neospora caninum in milk of ruminants by molecular method. Journal of Veterinary Microbiology, 15(2): 101-110.
Ansari-Lari, M., Rowshan, A., Jesmani, H., Masoudian, M. and Badkoobeh, M. (2017). Association of Neospora caninum with reproductive performance in dairy cows: a prospective study from Iran. Veterinary Research Forum, 8(2): 109-114.
Binaei, M., Changizi, E. and Staji, H. (2021). A serological study of Neospora caninum infection in dairy cattle in Semnan province, Iran. Journal of Veterinary Research, 76(1): 1-7. [In Persian]
Chryssafidis, A.L., Soares, R.M., Rodrigues, A.A.R., Carvalho, N.A.T. and Gennari, S.M. (2011). Evidence of congenital transmission of Neospora caninumin naturally infected water buffalo (Bubalus bubalis) fetus from Brazil. Parasitology Research, 108(3): 741-743.
Dalimi, A., Sabevarinejad, G., Ghafarifar, F. and Forouzandeh-Moghadam, M. (2014). Molecular detection of Neospora caninum from naturally infected dogs in Lorestan province, West of Iran. Archive Razi Institute, 69(2): 185-190.
Doosti, A., Khamesipour, F., Nekoei, S. and Lutvikadic, I. (2015). Survey for the presence of Neospora caninum in frozen bull’s semen samples by PCR assay. Asian Pacific Journal of Tropical Disease, 5(1): 7-12.
Dubey, J.P. (2003a). Review of Neospora caninum and neosporosis in animals. Korean Journal of Parasitology, 41: 1-16.
Dubey, J.P. (2003b). Neosporiosis in cattle. Journal of Parasitology, 89(1): 42-46.
Dubey, J.P., Sreekumar, C., Knickman, E., Miska, K.B., Vianna, M.C.B. and Kwok, O.C.H. (2004). Biologic, morphologic, and molecular characterization of Neospora caninum isolates from littermate dogs. International Journal of Parasitology, 34(10): 1157-1167.
Dubey, J.P., Schares, G. and Ortega-Mora, L. (2007). Epidemiology and control of neosporosis and Neospora caninum. Clinical Microbiology Reviews, 20(2): 323-367.
Dubey, J.P., Jenkins, M.C., Rajendran, C., Miska, K., Ferreira, L.R., Martins, J., Kwok, O.C.H. and Choudhary, S. (2011a). Gray wolf (Canis lupus) is a natural definitive host for Neospora caninum. Veterinary Parasitology, 181(2-4): 382-387.
Dubey, J.P. and Schares, G. (2011b). Neosporosis in animals—the last five years. Veterinary Parasitology, 180(1-2): 90-108.
Gharedaghi, Y. (2012). Seroprevalence of Neospora caninum in stray dogs of Tabriz Iran. Journal of Animal and Veterinary Advanced, 11(6): 723-726.
Gharekhani, J., Heidari, H. and Akbarein, H. (2012). Seroepidemiology of Neospora caninum in Iranian native and crossbreed cattle: across sectional study. Journal of Veterinary Research, 67(4): 325-329.
Gharekhani, J. and Heidari, H. (2014). Detection of anti-Neospora caninum antibodies in Iranian native cattle. Journal of Advanced Veterinary and Animal Research, 1(4): 228-231.
Gharekhani, J., Yakhchali, M. and Khaltabadi-Farahani, R. (2020). Prevalence and risk factors associated to Neospora caninum (Apicomplexa: Toxoplasmatidae) in pet dogs from Hamadan, West of Iran. Avicenna Journal of Clinical Microbiology Infection, 7(1): 22-26.
Habibi, G.R., Hashemi-Fesharki, R., Sadrebazzaz, A., Bozorgi, S. and Bordbar, N. (2005). Semi-Nested PCR for diagnosis of Neospora caninum infection in cattle. Archive Razi Institue, 59(2): 55-64.
Hadadi, M.R., Sherafati, R., Delavari, M., Arbabi, M., Gilasi, H.R. and Abed, A. (2018). Evaluation of anti-Neospora caninum antibody presence in cow’s milk in Kashan. Feyz: (Journal of Kashan University of Medical Sciences), 22(3): 333-338. [In Persian]
Haddadzadeh, H., Sadrebazzaz, A., Malmasi, A., Ardakani, H.T., Nia, P.K. and Sadreshirazi, N. (2007). Seroprevalence of Neospora caninum infection in dogs from rural and urban environments in Tehran, Iran. Parasitology Research, 101(6): 1563-1565.
Hamidinejat, H., Mosalanejad, B., Avizeh, R., Jalali, R., Hosseini, M., Ghorbanpour, M. and Namavari, M. (2011) .Neospora caninum and Toxoplasma gondii antibody prevalence in Ahvaz feral cats. Iranian.Jundishapur Journal of Microbiology, 4(4): 217-222.
Hashemi Fesharaki, S.R. (2009).Neospora caninum and neosporosis. Pasouk Publication, 1-23.
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Shirian, S. (2017). Molecular and serological detection of Neospora caninum in multiple tissues and CSF in asymptomatic infected stray dogs. Iranian Journal of Veterinary Medicine, 11(2): 105-112.