Binding Data Analysis for Interaction of n- Alkyl Sulfates with Insulin

Subject Areas : Journal of Physical & Theoretical Chemistry

M. Keshavarz ¹ (Not-mentioned)
A.K Bordbar ² (Not-mentioned)
K Zare ³ (Not-mentioned)
H. Aghaei ⁴ (Not-mentioned)

Received: 2015-04-24 Accepted : 2015-04-24 Published : 2004-08-01

Keywords: Insulin, n–Alkyl sulfates, Surfactant, Hill equation, Electrostatic interaction, Hydrophobic&#x0D, &#x0D, interaction,

Abstract :

The binding data for interaction of a homologous series of n-alkyl sulfates with alkyl chainlengths from C8 to C12 with insulin were analyzed on basis of Hill equation for two classes ofbinding sites .The intrinsic Gibbs free energies were calculated and resolute on basis ofelectrostatic and hydrophobic contributions The estimation of these contributions reveals themajor role of electrostatic interactions on first binding set and the minor one in the second.

References:

Sepration and determination trace amount of cadmium ions in real and water samples by cloud point extraction - flame atomic absorption spectrophotometry after preconcentration with non-ionic surfactant Triton-X114
Print Date : 2018-01-01
QSAR study of camptothecin derivatives as anticancer drugs using genetic algorithm and multiple linear regression analysis
Print Date : 2023-03-01
Electroanalysis of Trace Amount Hg2+ Ion in Water Samples Using Sensor Co3O4-CeO2-ZnO/CPE and Square Wave Anodic Stripping Voltammetry (SWASV) Method
Print Date : 2022-02-01
Ultrasonic Assisted Removal of humic acids (HAs) from aqueous solutions on Uultrasonically polysulfone/ X% Fe2O3 mixed matrix membrane, An Experimental Design Methodology
Print Date : 2022-10-01
Investigation of Silicon Nanowires Roles in Solar Cells
Print Date : 2022-10-01
Quantitative Structure-Property Relationship to Predict Quantum Properties of Monocarboxylic Acids By using Topological Indices
Print Date : 2016-11-01

Share To

Article Url

Binding Data Analysis for Interaction of n- Alkyl Sulfates with Insulin