Poly zirconium chloride (PZC) as an efficient adsorbent for 99 MO

Subject Areas : Journal of Physical & Theoretical Chemistry

H. Salehi ¹ , M. Zoghi ² , M. Alimoradi ³ , A. Niazi ⁴ , H. Abbasi ⁵

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Received: 2015-05-09 Accepted : 2015-05-09 Published : 2008-11-01

Keywords: 99Mo I 99mTc generator, poly zirconium chloride, Radiopharmaceutical, 99Mo adsorbent,

Abstract :

This radionuclide is almost exclusively produced from the decay of its parent 99Mo. 99mTc is themost available and important nuclide used as a diagnostic agent in nuclear medicine. To develop anewly practical 99mTc generator using ( n,y ) 99Mo, an inorganic polymer adsorbent has beendeveloped framed with oxygen-zirconium-chlorine bonds with a high adsorption of Mo, Thepolyzirconium adsorbent was named PZC ( poly zirconium chloride) which made clear that PZChas an ability and high performance as a practical adsorbent for 99mTc generator using ( n, y)99Mo. The amount of 99Mo adsorbed to PZC reached about 250mg/g PZC. 99mTc was elutedwith a small volume of saline solution in the yield of about 76.43 %. The breakthrough of 99Moin the elution of 99mTc was less than 0.015%.