Molecular Dynamics Simulation of Water Transportation through Aquaporin-4 in Rat Brain Cells

Subject Areas : Journal of Physical & Theoretical Chemistry

F. Kaveh ^{1
*} , K. zare ^{2
*} , S. Salemi ^{3
*} , A. R. Illchani ^{4
*} , N. Khodayari ^{5
*}

1 - -
2 - -
3 - -
4 - -
5 - -

Received: 2015-05-09 Accepted : 2015-05-09 Published : 2009-02-01

Keywords: Aquaporin-4, Brain edema, Molecular Dynamics, CHARMM,

Abstract :

This paper investigates the mechanism of water transportation through aquaporin-4(AQP4) of ratbrain cells by means of molecular dynamics simulation with CHARMM software. The AQP4 wasembedded into a bilayer made of Dimystroilphosphatylcholine (DMPC). The results illustrate thatwater molecules move through AQP4's channel with change of orientation of oxygen of eachwater molecule.

References:

Sepration and determination trace amount of cadmium ions in real and water samples by cloud point extraction - flame atomic absorption spectrophotometry after preconcentration with non-ionic surfactant Triton-X114
Print Date : 2018-01-01
QSAR study of camptothecin derivatives as anticancer drugs using genetic algorithm and multiple linear regression analysis
Print Date : 2023-03-01
Electroanalysis of Trace Amount Hg2+ Ion in Water Samples Using Sensor Co3O4-CeO2-ZnO/CPE and Square Wave Anodic Stripping Voltammetry (SWASV) Method
Print Date : 2022-02-01
Ultrasonic Assisted Removal of humic acids (HAs) from aqueous solutions on Uultrasonically polysulfone/ X% Fe2O3 mixed matrix membrane, An Experimental Design Methodology
Print Date : 2022-10-01
Investigation of Silicon Nanowires Roles in Solar Cells
Print Date : 2022-10-01
Quantitative Structure-Property Relationship to Predict Quantum Properties of Monocarboxylic Acids By using Topological Indices
Print Date : 2016-11-01

Share To

Article Url

Molecular Dynamics Simulation of Water Transportation through Aquaporin-4 in Rat Brain Cells