The relationship between physical activity and drug treatments and biochemical factors of non-alcoholic fatty liver diseases in firefighters with a history of covid-19
Subject Areas : Journal of Physical Activity and Hormones
Ali Reza Zeyaee
1
,
Homa Sheikhani Shahin
2
*
,
Eskandar Rahimi
3
1 - MS student of sports physiology, Zand Higher Education Institute, Shiraz, Iran
2 - Associate of sport physiology, Department of sport Science, Zand Higher Education Institute, shiraz, Iran
3 - Assistant of sport physiology, Department of sport Science, Zand Higher Education Institute, shiraz, Iran
Keywords: Physical activity, Non-alcoholic fatty liver disease, Liver enzymes, Covid-19, Firefighters,
Abstract :
Introduction: The purpose of this study was to investigate the relationship between physical activity and drug treatments with biochemical factors of non-alcoholic fatty liver disease (NAFLD) in firefighters with a history of covid-19.
Material & Methods: In the present study, all firefighters of the Shiraz city fire department were matched based on age and body mass index (BMI) to determine the history of covid-19 infection and the use of related drugs and the prevalence of NAFLD among them was investigated. The statistical sample for this research was 38 people. After identifying people with NAFLD with a history of covid-19, they were asked to complete the Baecke physical activity questionnaire (BPAQ) to record their daily physical activity. After collecting the data, Pearson's test was used to determine the correlation between physical activity levels and biochemical factors related to NAFLD (P<0.05).
Results: The findings showed that there was a significant correlation between physical activity and drug treatments. Weight (P=0.03), body mass index (P=0.035), AST (P=0.041), ALP (P=0.038), bilirubin (P=0.039) and albumin (P=0.048) were examined in firefighters with NAFLD with a history of covid-19.
Conclusion: According to the study results, it can be concluded that daily physical activity should be increased in this statistical population to have a greater effect on NAFLD recovery and reduce the use of drugs and their side effects.
1. Faulkner J, O’Brien WJ, McGrane B, Wadsworth D, Batten J, Askew CD, et al. Physical activity, mental health and well-being of adults during initial COVID-19 containment strategies: A multi-country cross-sectional analysis. J Sci Med Sport. 2021;24(4):320-6. doi: 10.1016/j.jsams.2020.11.016.
2. Sallis JF, Adlakha D, Oyeyemi A, Salvo D. An international physical activity and public health research agenda to inform COVID-19 policies and practices. J Sport Health Sci. 2020;9(4):328-334. doi: 10.1016/j.jshs.2020.05.005.
3. Tison GH, Avram R, Kuhar P, Abreau S, Marcus GM, Pletcher MJ, et al. Worldwide effect of COVID-19 on physical activity: a descriptive study. Ann Intern Med. 2020;173(9):767-70. doi: 10.7326/M20-2665.
4. Favre G, Legueult K, Pradier C, Raffaelli C, Ichai C, Iannelli A, et al. Visceral fat is associated to the severity of COVID-19. Metabolism. 2021;115:154440. doi: 10.1016/j.metabol.2020.154440.
5. Soteriades ES, Hauser R, Kawachi I, Christiani DC, Kales SN. Obesity and risk of job disability in male firefighters. Occup Med (Lond). 2008;58(4):245-50. doi: 10.1093/occmed/kqn023.
6. Kales SN, Soteriades ES, Christophi CA, Christiani DC. Emergency duties and deaths from heart disease among firefighters in the United States. N Engl J Med. 2007;356(12):1207-15. doi: 10.1056/NEJMoa060357.
7. Soteriades ES, Smith DL, Tsismenakis AJ, Baur DM, Kales SN. Cardiovascular disease in US firefighters: a systematic review. Cardiol Rev. 2011;19(4):202-15. doi: 10.1097/CRD.0b013e318215c105.
8. Paley CA, Johnson MI. Abdominal obesity and metabolic syndrome: exercise as medicine? BMC Sports Sci Med Rehabil. 2018;10:7. doi: 10.1186/s13102-018-0097-1.
9. De Sousa S. Metabolic syndrome, diet and exercise. Best Pract Res Clin Obstet Gynaecol. 2016;37:140-51. doi: 10.1016/j.bpobgyn.2016.01.018.
10. Momghani E, Mehrangiz FA, Noormohammadi M, Daftari N. Prevalence of metabolic syndrome in firemen of Tabriz city. J Kermanshah Univ Med Sci. 2011;15(4):296-302.
11. Chatripour R, Sadeghi Rad K, Sharifi H, Jorvand R. Comparison of the Prevalence of Metabolic Syndrome in Military and Non-Military (civilian) Personnel and Its Relationship with Lifestyle. J Mil Med. 2022;23(4):358-66. doi: 10.30491/JMM.23.4.358.
12. Mansouri J, Fathi, Attarzadeh Hosseini. The effect of increasing age and overweight on biomotor indicators and cardiovascular risk factors of Mashhad firefighters. In: The second national conference of sports diseases; 2017.
13. Mohammadi A, Khodaei K, Badri N. Association between the prevalence of metabolic syndrome and physical activity at work, leisure time and during exercise among over 30 years old male students in Sabzevar (Case Study of Applied Science University). J Sabzevar Univ Med Sci. 2019;26(1):53-61.
14. Shirvani H, Rostamkhani F. Exercise considerations during coronavirus disease 2019 (COVID-19) Outbreak: A narrative review. J Mil Med. 2020;22(2):161-8. doi: 10.30491/JMM.22.2.161.
15. Nieman DC, Wentz LM. The compelling link between physical activity and the body's defense system. J Sport Health Sci. 2019;8(3):201-17. doi: 10.1016/j.jshs.2018.09.009.
16. Baecke JA, Burema J, Frijters JE. A short questionnaire for the measurement of habitual physical activity in epidemiological studies. Am J Clin Nutr. 1982;36(5):936-42. doi: 10.1093/ajcn/36.5.936.
17. Eslami L, Rahmani Nia F, Nakhostin Roohi B. The effect of 12 week vitamin E supplementation and regular physical activity on selected liver enzymes of non-alcoholic fatty liver patients. Sport Physiol. 2014;6(23):69-82.
18. Minaeifar AA, Rassekh F, Baghiani A. The role of physical activity on blood factors, lipid profile, and liver enzymes of tile factory workers (A Case Study). TKJ. 2020;12(2):47-58.
19. Sedighi S, Hosseini S. Comparison of the Therapeutic Effect of Gingerbread Hydroalcoholic Extract with Physical Activity on the Level of Transaminases and on Liver Tissue Changes in Adult Male Rats with Non-Alcoholic Fatty Liver Disorder. Armaghane Danesh. 2018;23(2):188-201.
20. Shamsoddini A, Sobhani V, Ghamar Chehreh ME, Alavian SM, Zaree A. Effect of Aerobic and Resistance Exercise Training on Liver Enzymes and Hepatic Fat in Iranian Men With Nonalcoholic Fatty Liver Disease. Hepat Mon. 2015;15(10):e31434. doi: 10.5812/hepatmon.31434.
21. Hallsworth K, Thoma C, Moore S, Ploetz T, Anstee QM, Taylor R, et al. Non-alcoholic fatty liver disease is associated with higher levels of objectively measured sedentary behaviour and lower levels of physical activity than matched healthy controls. Frontline Gastroenterol. 2015;6(1):44-51. doi: 10.1136/flgastro-2014-100432.
22. Zar A, Hosseini SA, Homaion A. Effect of Eight-Week Aquagymnastic Training on Liver Enzymes and Lipid Profile of Middle-Aged Women. Qom Univ Med Sci J. 2016;10(7):29-37.
23. Ryu S, Chang Y, Jung H-S, Yun KE, Kwon M-J, Choi Y, et al. Relationship of sitting time and physical activity with non-alcoholic fatty liver disease. J Hepatol. 2015;63(5):1229-37. doi: 10.1016/j.jhep.2015.07.010.
24. Kwak M-S, Kim D, Chung GE, Kim W, Kim YJ, Yoon J-H. Role of physical activity in nonalcoholic fatty liver disease in terms of visceral obesity and insulin resistance. Liver Int. 2015;35(3):944-52. doi: 10.1111/liv.12552.
25. Duvivier BM, Schaper NC, Bremers MA, Van Crombrugge G, Menheere PP, Kars M, et al. Minimal intensity physical activity (standing and walking) of longer duration improves insulin action and plasma lipids more than shorter periods of moderate to vigorous exercise (cycling) in sedentary subjects when energy expenditure is comparable. PLoS One. 2013;8(2):e55542. doi: 10.1371/journal.pone.0055542.
26. Lee Y-h, Jung KS, Kim SU, Yoon H-j, Yun YJ, Lee B-W, et al. Sarcopaenia is associated with NAFLD independently of obesity and insulin resistance: Nationwide surveys (KNHANES 2008–2011). J Hepatol. 2015;63(2):486-93. doi: 10.1016/j.jhep.2015.02.051.
27. Kenneally S, Sier JH, Moore JB. Efficacy of dietary and physical activity intervention in non-alcoholic fatty liver disease: a systematic review. BMJ Open Gastroenterol. 2017;4(1):e000139. doi: 10.1136/bmjgast-2017-000139.