Modeling the human retina in patients with glaucoma

Subject Areas : Smart & Advanced Materials

افسانه صافدل ¹ , کامران حسنی ²

1 - Department of Biomechanics,South Tehran Branch,Islamic Azad University,Tehran,Iran
2 - دانشیار دانشگاه آزاد واحد علوم تحقیقات دانشکده علوم و فناوری‌های پزشکی

Received: 2021-03-08 Accepted : 2021-03-08 Published : 2020-09-01

Keywords: Finite Element Method, Stress, Glaucoma, Intraocular pressure, Retina,

Abstract :

Glaucoma is a major risk factor for blindness and causes loss of visual field due to retinal ganglion cell (RGC) destruction. Glaucoma is associated with high blood pressure, cardiovascular disease, and ocular blood flow. Vascular factors play an important role in the development of glaucoma. A number of retinal vascular parameters are measured for use in software from retinal imaging. The biomechanical model of the disease reveals that mechanical stress induced by IOP impairs the function of retinal ganglion cells. Due to the difficulty of direct retinal biomechanical measurement in determining ocular biomechanics, the current study uses modeling with significant limitations to make it easier to examine.The purpose of this article is to stimulate the human retina in patients with glaucoma. In this research, the applied stresses on the inner surfaces of the retina and its effects on the inner parts are studied. Intraocular pressure (IOP) is considered to be higher than 20 mm Hg. With this model, we can study stresses and strains in different and desired conditions. The way of applying load is compressive load on the retina