Comparison of antibacterial activity of Eucalyptus globulus Labill. and Malva neglecta Wallr.
Subject Areas : Journal of Medicinal Herbs, "J. Med Herb" (Formerly known as Journal of Herbal Drugs or J. Herb Drug)
مجید
دوست محمدی
1
(دانشگاه آزاد اسلامی، واحد زنجان، گروه میکروبیولوژی، زنجان، ایران)
پیمان
عبداله زاده
2
(دانشگاه آزاد اسلامی، واحد زنجان، باشگاه پژوهشگران جوان، زنجان، ایران)
حامد
علیزاده
3
(دانشگاه آزاد اسلامی، واحد زنجان، باشگاه پژوهشگران جوان، زنجان، ایران)
Keywords: Extract, Antibiotic resistance, Malva neglecta, Herbal drugs, Eucalyptus globulus,
Abstract :
Background & Aim: Very studies results show that many plants can be used safety and successfully to treat bacterial diseases without presenting the disadvantages affects and antibiotic resistance. Eucalyptus globulus and Malva neglecta are native plants in Iran that due to containing different chemical compounds have been antimicrobial activity against some bacteria. The aim of this study is comparison of antibacterial effects of Eucalyptus globulus and Malva neglecta extracts on Staphylococcus aureus, Enterococcus faecalis, Salmonella typhimurium and Pseudomonas aeruginosa.Experimental: In this study, at the first time aquatic, ethanolic, acetonic and chlorophormic extracts of E. globulus and M. neglecta dried leaves prepared. Then MIC and MBC of the extracts for the bacteria with micro-dilution method and well diffusion method performed for dosage depending effect.Results & Discussion: The results showed that both plant extracts have antimicrobial activity against bacteria, but antibacterial activity of various extracts of E. globulus is more than M. neglecta extracts and, this extracts can be used in the manufacture of new drugs of plant origin.Industrial/Practical recommendation: According to antimicrobial effects of Eucalyptus globulus and Malva neglecta extracts in this study recommended after human studies, it is prepared herbal drug from this plant and presented.
Aslangul, E., Massias, L., Meulemans, A., Chau, F., Andremont, A., Courvalin, P., Fantin, B. and Ruimy, R. 2006. Acuired gentamicin resistance by permeability impairment in Enterococcus faecalis. Antimicrob Agents Chemother., 50: 3615-21.
Bodey, G.P. and Fainstein, V. 1986. Infections of the gastrointestinal tract in the immunocompromised patient. Annu Rev Med., 37: 271-81.
Calvert, N., Stewart. W. C. and Reilly, W. J. 1998. Salmonella typhimurium DT 104 infection in people and animals in Scotland: a collaborative epidemiological study 1993-96. Vet Rec., 143 (13): 351-4.
Chambers, H. F. 1997. Methicillin resistance in staphylococci: molecular and biochemical basis and clinical implications. Clin. Microbiol. Rev., 10: 781–791.
Cowan, M. M. 1999. Plant products as antimicrobial agents. Clin. Microbiol. Rev., 12: 564-582.
Driscoll, J.A., Brody, S.L. and Kollef, M.H. 2007. The epidemiology, pathogenesis and treatment of Pseudomonas aeruginosa infections. Drugs., 67: 351-368.
Dulgar, B. and Gonuz, A. 2004. Antimicrobial activity of certain plants used in Turkish traditional medicine. Asian Journal of Plant Sciences., 3 (1): 104-107.
Igbal, A. and Beg, A.Z. 2001. Antimicrobial and phytochemical studies on 45 Indian medicinal plants against multi-drug resistant human pathogens. J Ethnopharmacol., 74 (2): 113-123.
Kluytmans, J., Van Belkum, A. and Verbrugh, H. 1997. Nasal carriage of Staphylococcus aureus: epidemiology, underlying mechanisms, and associated risks. Clin Microbial Rev., 10 (3): 505-520.
Lamb, V. A., Mayhall, C. G., Spadora, A. C., Markowitz, S. M., Farmer, J. J. and Dalton, H. P. 1984. Outbreak of Salmonella typhimurium gastroenteritis due to an imported strain resistant to ampicillin, chloramphenicol, and trimethoprim-sulfamethoxazole in a nursery. J Clin Microbiol., 20 (26): 1076-79.
Lepage, P., Bogarest, J., Nsengumuremyi, F., Van Goethem, C., Hitimana, D. G., Vandepitte, J., Butzler, J.P. and Levy, J. 1986. Metastatic focal infections due to multi-resistant Salmonella typhimurium in children: a 34 month experience in Rwanda. Eur. J. Epidemiol., 2 (2): 99-103.
Mitscher, L. A., Drake, S., Golloapudi, S. R. and Okwute, S.K. 1987. A modern look at folkloric use of anti infective agents. J Nat Prod., 50(6): 1025-1040.
Mohsen Nezhad, F., Zeighami, H., Mota, A., Sattari, M. and Yadegar, A. 2009. Antibacterial activity of Eukalyptus extracts on methicillin resistance Staphylococcus aureus. Res J Biol Sci., 4 (8): 905-908.
Moniri, R., Mosayebi, Z., Movahedian, A.H. and Mossavi, A. 2006. Increasing trend of antimicrobial drug-resistance in Pseudomonas aeruginosa causing septicemia. Iranian Journal of Public Health., 35: 58-62.
Mulyaningsih, S., Sporer, F., Zimmermann, S., Reichling, J. and Wink, M. 2010. Synergistic properties of the terpenoids aromadendrene and 1,8-cineole from the essential oil of Eucalyptus globulus against antibiotic-susceptible and antibiotic-resistant pathogens. Phytomedicine., 17(13): 1061–1066.
Rosario, R., and Beatriz, B. 2003, Antimicrobial activity of selected Peruvian medicinal plants. Journal of Ethnopharmacology., 88: 199–204.
Satish, S., Mohana, D.C., Raghavendra, M.P., And Raveesha, K.A. 2007, Antifungal activity of some plant extracts against important seed borne pathogens of Aspergillus sp. J Agr Technol., 3(1): 109-119.
Seyyednejad, M., koochak, H., Darabpour, E., and Motamedi, H. 2010. A Survey on Hibiscus rosa-sinensis, Alcea rosea L. and Malva naglecta Wallr as antimicrobial agents. Asian pacific Journal of Tropical Medicine., 351-355.
Shahidi Bonjar. 2004. Evaluation of antibacterial properties of some medicinal plants used in Iran. Journal of Ethnopharmacology., 94: 301–305.
Shale, TL., Stirk, W.A., and Staden, J.V. 2005. Variation in antibacterial and anti-inflammatory activity of different growth forms of Malva parviflora and evidence for synergism of the anti-inflammatory compounds, Journal of Ethnopharmacology., 96: 325–330.
Shopsin, B., and Kreiswirth, B. 2001. Molecular epidemiology of methicillinresistant Staphylococcus aureus. Emerg Infect Dis., 7 (2): 323-326.
Srinivasan, D., Nathan, S., Suresh, T., and Lakshmana Perumalsamy, P. 2001. Antimicrobial activity of certain Indian medicinal plants used in folkloric medicine. J Ethnopharmacol., 74: 217–220.
Tankovic, J., Mahjoubi, F., Courvalin, P., Duval, J., and Leclerco, R. 1996. Development of fluoroquinolone resistance in Enterococcus faecalis and role of mutations in the DNA gyrase gyrA gene. Antimicrob.Agents Chemother., 40(11): 2558-61.
Trujillano-Martín, I., García-Sánchez, E., Martínez, I.M., Fresnadillo, M.J., García-Sánchez, J.E., and García-Rodríguez, J.A. 1999. In vitro activities of five new antimicrobial agents againts Brucella melitensis. Int J Antimicrob Agxents., 12(2): 185-186.
Wachino, J., Doi, Y., Yamane, K., Shibata, N. ,Yagi, T., Kubota, T., et al. 2004. Nosocomial spread of ceftazidime resistant strains producing a novel class A -lactamase, GES-3, in a neonatal intensine care unite in Japan. Ant Agents and Chemother., 48:1960-1967.
Yan, J., Kasi, S., and Chuang, C. 2004. Epidemiological investigation of bloodstream infections by extended spectrum cephalospoyin resistant in a Taiwanese teaching hospital. J Clin Microbiol., 42: 3329-3332