The study of antioxidant potential of Morus alba L. leaves extract
Subject Areas : Journal of Medicinal Herbs, "J. Med Herb" (Formerly known as Journal of Herbal Drugs or J. Herb Drug)پریسا صدیق آرا 1 , عباس برین 2
1 - دانش آموخته دکتری تخصصی سم شناسی دانشکده دامپزشکی، دانشگاه تهران، تهران، ایران
2 - استاد دانشکده دامپزشکی، دانشگاه تهران، تهران، ایران؛
Keywords: Lipid peroxidation, Antioxidant, Morus alba, free radicals,
Abstract :
Background & Aim: Applications of synthetic antioxidant in food have side effects. In present study, the antioxidant potential of Morus alba leaves, as natural antioxidant, was screened with cupric ion reducing assay (CUPRAC assay) and inhibition of lipid peroxidation. The aim of this study was to determine the total antioxidant activity of Morus alba leaves.Martial & Methods: The first, total antioxidant activity of Morus alba leaves was determined in two phase; water and methanol extracts by CUPRAC assay and compared with Rosmarinus officinals extract as positive control. In second step, methanol extract of Morus alba leaves was evaluated by lipid peroxidation inhibition of lipids in egg-yolk. CuSo4 induced this lipid peroxidation.Results & Discussion: In CUPRAC assay, Morus alba leaves have antioxidant activity more Rosmarinus officinals. In addition, the methanol extracts of Morus alba leaves can inhibit lipid peroxidation of lipid in egg-yolk. There was significant difference (p ≤ 0.05) between groups.Conclusion: Our results indicated that Morus alba leaves are a good source of natural antioxidants.
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