Some Biochemical Parameters and Level of Preptin in Newly Diagnosed Type 2 Diabetic Women Patients in Tikrit City

Subject Areas : Journal of Chemical Health Risks

Firas Faris Rija ¹ , Marwah Isam Sulaiman Musa ² , Hind T. Hamad ³

1 - Department of Biology, College of Science, Tikrit University, Tikrit, Iraq
2 - Department of Biology, College of Science, Tikrit University, Tikrit, Iraq
3 - Department of Prostheses, Al-Dour Technical Institute, Northern Technical University, Saladin, Iraq

Received: 2021-03-29 Accepted : 2021-06-25 Published : 2022-06-01

Keywords: HbA1c, Diabetes, Preptin, Type 2 DM, Mellitus,

Abstract :

A chronic disease categorized by high blood sugar called diabetes mellitus (DM), Its prevalence is rapidly increasing all over the world. Peptin is a peptide produced by cells of pancreas. It plays as a physiologic enhancer of glucose-mediated insulin secretion. There, the current study aimed to note differences in the levels of newly diagnosed patients with T2DM controls. This study was directed at Salah el-Deen medical Clinic in Tikrit city and included women from Salah al-Din Hospital in Tikrit in the period since Feb to Jul 2020, 40 newly diagnosed patients T2DM and 40 healthy elderly women. Preptin, Hba1c, fasting blood glucose (FBS), blood urea (BU), and serum creatinine levels will be examined. The present study discovered a significant rise in Preptin (362.460.01pg ml-1), Hba1c (8.82.7 %), FBS (205±25.7mg dl-1), BU (20.71 ±4.3 mmol l-1), and creatinine (1.1±0.2mg dl-1) in female T2DM patients compared to the control group (222.8±30.7pg ml-1, 4.6±1.3 %, 99±15. The observed link between preptin level and diabetes mellitus a suggests that this peptide may play a role in the pathogenesis of DM, which may be of particular interest to a group DM that constitutes a major public health problem.

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