Application of 2-methylpyridinum p-toluenesulfonate ([2-MPy][p-TSA]) as an efficient catalyst for the one-pot synthesis of hexahydroquinolines-3-carboxamides

Subject Areas : Polymer

Matin Asadi ¹ , Masoud Mokhtary ²

1 - Department of Chemistry, Rasht Branch, Islamic Azad University, Rasht, Iran
2 - Department of Chemistry, Rasht Branch, Islamic Azad University, Rasht, Iran

Received: 2018-12-22 Accepted : 2018-12-22 Published : 2018-10-01

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Abstract :

2-Methylpyridinum p-toluenesulfonate ([2-MPy][p-TSA]) as a novel room temperature ionic liquidwas synthesized and evaluated as a recoverable catalyst for the one-pot synthesis ofhexahydroquinoline-3-carboxamide derivatives by four-component reaction of arylaldehydes,dimedone, acetoacetanilide and ammonium acetate in high to excellent yield in ethanol at 50 oC.The [2-MPy][p-TSA] catalyst was characterized via FT-IR, 1H NMR and 13C NMR spectroscopy.An environmentally benign procedure, four-component in one pot reaction, high yields and simplepreparation of the catalyst are some advantages of this work.