A Simple, Practical and Efficient Method for the Synthesis of New Disubstituted 1,3,4-oxadiazoles
Subject Areas : PolymerAli Ramazani 1 , Delnia Zamanesazi 2 , Yavar Ahmadi 3 , Pegah Azimzadeh Asiabi 4 , Ali Souldozi 5 , Sang Woo Joo 6
1 - Department of Chemistry, University of Zanjan, Zanjan, Iran
2 -
3 - North West Reseach Complex, Nuclear Science and Technology Research Institute, Bonab, Iran
4 - Department of Chemistry, University of Zanjan, Zanjan, Iran
5 - Department of Chemistry, Urmia Branch, Islamic Azad University, Urmia, Iran
6 -
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Abstract :
Reactions of N-isocyaniminotriphenylphosphorane with α- chloroketones in the presence ofaromatic carboxylic acids proceed smoothly at room temperature and in neutral conditions toafford new disubstituted 1,3,4-oxadiazole derivatives in high yields.