Solvent-Free Multicomponent Reactions of Dithiocarbamates, Activated Acetylenes and Isocyanides

Subject Areas : Polymer

F. Rostami-Charati ¹ , Z. Hossaini ² , R. Hajinasiri ³

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Received: 2015-11-17 Accepted : 2015-11-17 Published : 2012-01-01

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Abstract :

An efficient method to synthesis the 2H-pyrans using three component reactions of dithiocarbamats, activated acetylenes and isocyanides in water as the solvent is described. In these reactions, synthesis of 2H-pyrans is possible based on the one-pot reaction and without using any catalyst. The mild reaction conditions and high yields of the products exhibit synthetic advantage of these methods.