Application of Green Procedure for the Synthesis of Substituted Pyrroles: Multi-component Reaction of Oxalyl Chloride

Najafi, Maedeh; Pahlavan, Rokhsar; Hossaini, Zinatossadat

Manuscript ID : 518043 Visit : 335 Page: 41 - 45

20.1001.1.20083815.2015.9.4.4.7

Article Type: Original Research

Application of Green Procedure for the Synthesis of Substituted Pyrroles: Multi-component Reaction of Oxalyl Chloride

Subject Areas : Polymer

Maedeh Najafi ¹ , Rokhsar Pahlavan ² , Zinatossadat Hossaini ³

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Received: 2015-12-28 Accepted : 2015-12-28 Published : 2015-10-01

Keywords:

Abstract :

A novel, convenient and efficient approach to synthesis of pyrrole derivatives via the reaction of primary amines, alkyl propiolates and oxalyl chloride is described. The method offers several advantages including high yields of products and performing reaction in water as the solvent.

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Application of Green Procedure for the Synthesis of Substituted Pyrroles: Multi-component Reaction of Oxalyl Chloride