Tannic acid: A Green Catalyst for the Eco-friendly Synthesis of 2,3-dihydroquinazolin-4(1H)-ones under Solvent Free Conditions

Subject Areas : Polymer

Mahdim Narouei ¹ , Nourallah Hazeri ² , Ebrahim Molashahi ³ , Sara Zhaleh ⁴ , Maryam Fatahpour ⁵

1 - Department of Chemistry, Faculty of Sciences, University of Sistan and Baluchestan, Zahedan, Iran
2 - Department of Chemistry, Faculty of Sciences, University of Sistan and Baluchestan, Zahedan,Iran
3 - Department of Chemistry, Faculty of Sciences, University of Sistan and Baluchestan, Zahedan,Iran
4 - Department of Chemistry, Faculty of Sciences, University of Sistan and Baluchestan, Zahedan,Iran
5 - Department of Chemistry, Faculty of Sciences, University of Sistan and Baluchestan, Zahedan,Iran

Received: 2017-12-24 Accepted : 2017-12-24 Published : 2017-10-01

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Abstract :

A new, facile, cost effective, and eco-friendly protocol is reported for the synthesis of 2,3-dihydroquinazoline-4-(1H)-ones exploring tannic acid as a novel, inexpensive, andbiodegradable catalyst. A variety of dihydroquinazolins were prepared from aromatic aldehydesand anthranilamide using catalytic amount of tannic acid under solvent free conditions.Operational simplicity, high yield, and high atom-economy are the important features of thisprotocol.