Green synthesis of amide derivatives by using activated acetylenic compounds and 4-aminocumarines
Subject Areas :
Keywords: Lactams, Aniline, Naphthol amin, Dialkyl acetylenedicarboxylates.,
Abstract :
The reaction between activated acetylenic compounds and various primary aromatic amines in the presence of Et3N leads to lactam derivatives in good yields. The present protocol offers the advantages of clean reaction, short reaction time, high yield, easy purification and performing without the catalyst.